Application of qi regulating and blood activating preparation in preparation of drug for prevention and treatment of acute coronary syndrome

A technology for coronary syndrome, regulating qi and promoting blood circulation, applied in the field of medicine, can solve problems such as unreported effects

Inactive Publication Date: 2015-05-06
GUIZHOU YIBAI PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As mentioned above, the effect of Liqi Huoxue preparation on coronary heart disease angina pectoris is good, but there is no report about the effect of Liqi Huoxue preparation in the treatment of acute coronary syndrome. Infarction, unstable angina and other diseases are of great significance

Method used

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  • Application of qi regulating and blood activating preparation in preparation of drug for prevention and treatment of acute coronary syndrome

Examples

Experimental program
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Effect test

experiment example

[0024] 1. Clinical data All cases are from the inpatients of Guiyang Medical College from January 2012 to April 2013. After being diagnosed with acute coronary syndrome, a total of 160 cases were randomly divided into treatment group 1 (regular western medicine + regulating qi and promoting blood circulation) ), treatment group 2 (conventional western medicine + quick-acting Jiuxin), treatment group 3 (conventional western medicine + Musk Baoxin), and control group (conventional western medicine), each with 40 cases; the treatment group: 70 males and 50 females, with an average age of (60.25±10.56) years old, the disease distribution was unstable angina (UA) in 87 cases, ST-segment elevation myocardial infarction (STEMI) in 18 cases, non-ST-segment elevation myocardial infarction (NSTEMI) in 15 cases, and then They were divided into three treatment groups, 40 cases in each group, and the difference was not significant; the control group: 23 males and 17 females, with an average...

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Abstract

Belonging to the field of medicine, the invention relates to application of a qi regulating and blood activating preparation in preparation of a drug for prevention and treatment of acute coronary syndrome. The qi regulating and blood activating preparation is prepared from 350-600 parts of Cinnamomum migao, 4-15 parts of borneol, 250-500 parts of Ligusticum wallichii, 25-50 parts of Allium macrostemon as the raw materials. Clinical experiments investigate patient angina pectoris, traditional Chinese medicine syndrome scoring, inflammatory indicators and other indexes, and experimental data show that the qi regulating and blood activating preparation can protect blood vessel injury, control inflammatory reaction and alleviate plaque formation and rupture, can significantly improve acute myocardial infarction caused by acute myocardial ischemia, unstable angina and other symptoms. Thus, the qi regulating and blood activating preparation can be used as an ideal drug for prevention and treatment of acute coronary syndrome.

Description

Technical field: [0001] The invention belongs to the field of medicine, and in particular relates to the application of a preparation for regulating qi and promoting blood circulation in the preparation of medicines for preventing and treating acute coronary syndrome. Background technique: [0002] Acute coronary syndrome (ACS) is a group of clinical syndromes caused by acute myocardial ischemia, including acute myocardial infarction ( AMI) and unstable angina (UA), in which AMI includes ST-segment elevation myocardial infarction and non-ST-segment elevation myocardial infarction; it is a major and common disease that seriously endangers human health. Coagulation activation and vulnerable plaque inflammation play an important role in the occurrence of ACS and are two core pathological links. The existence of atherosclerotic plaque in coronary arteries is the root cause of acute coronary syndrome, and the rupture of plaque is the direct cause of acute coronary syndrome. [...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8962A61K9/20A61P9/10A61K31/045
Inventor 窦啟玲
Owner GUIZHOU YIBAI PHARMA CO LTD
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