Method for measuring local pulse wave propagation speed of carotid blood vessel

Abstract

The invention relates to a method for measuring a local pulse wave propagation speed of a carotid blood vessel, which comprises the following steps: a step 1 of designing an ultrafast comb-tooth-shaped focus beam transmitting and receiving sequence and simultaneously acquiring a plurality of points of radio frequency echo signals in the long axis direction of the carotid blood vessel; a step 2 of identifying and tracking an echo signal of front and rear walls of the vessel in each scanning line after carrying out filtering preprocessing on a plurality of focus beam echo signals, which are simultaneously received, in the long axis direction of the carotid blood vessel; a step 3 of respectively carrying out one-dimensional self-correlation phase shifting estimation on adjacent frames of echo signals of the front and rear walls of the vessel in each scanning line to obtain a corresponding phase shifting speed waveform and then obtaining a corresponding phase shifting waveform of the vessel wall along with variation of a cardiac cycle in each scanning line; a step 4 of calculating relative time delay between the phase shifting waveforms of the vessel wall in the adjacent scanning lines and carrying out linear fitting on the time delay so as to obtain a reciprocal of a slope, i.e. the estimated local pulse wave propagation speed. The method provides new basis for early detection of the atherosclerosis.

Description

technical field [0001] The invention relates to the technical field of ultrasonic imaging, in particular to a method for measuring local pulse wave propagation velocity of carotid arteries based on an ultra-fast comb-shaped focused beam transmitting and receiving sequence. Background technique [0002] Decreased arterial elasticity is a comprehensive manifestation of early damage to the vessel wall by various factors, and it is a good specific and sensitive indicator of early vascular disease. At present, only B-ultrasound images and Doppler blood flow can be used to diagnose thickening of the vessel wall or the existence of plaques clinically at the stage of vascular structural lesions, and it is impossible to realize early detection and evaluation of quantitative atherosclerosis at the stage of vascular functional lesions . In 1878, Moens et al. derived the mathematical equation between pulse wave velocity (PWV) and elastic modulus, that is, the Moens-Korteweg equation, w...

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Problems solved by technology

However, the traditional B-ultrasound imaging mode is realized by sequentially focusing on transmitting and receiving scan lines one by one. The imaging frame rate of this imaging mode is only tens of hertz, whi

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