76 results about "Pulse wave propagation" patented technology

A blood pressure monitoring apparatus which continuously estimates and monitors the blood pressure by using the pulse wave propagation time can accurately estimate the blood pressure. While an estimated blood pressure is continuously calculated by using the pulse wave propagation time, the correlation between the pulse wave propagation time and the interval between feature points contained in two consecutive heart beat waveforms of an electrocardiogram is monitored. If the correlation is reversed, the blood pressure is actually measured, and the estimated blood pressure is corrected on the basis of the difference between the estimated blood pressure and actually measured blood pressure.

A heart-sound detecting apparatus, including: a heart-sound microphone which detects a plurality of heart sounds produced by a heart of a living subject and outputs a heart-sound signal representative of the detected heart sounds; a smoothing device for smoothing, by differentiation, a waveform of the heart-sound signal output from the heart-sound microphone; a squaring device for squaring an amplitude of the smoothed waveform with respect to a base line of the heart-sound signal; and a start-point determining device for determining a start point of a first heart sound I as one of the detected heart sounds, based on that the squared amplitude is greater than a prescribed threshold value.

A blood pressure monitoring system includes a blood pressure measurement device for measuring blood pressure using a cuff, a memory for storing an externally inputted pulse wave propagation time fluctuation threshold, a time interval detection reference point detection section for detecting a time interval detection reference point in a pulse wave on the side of aortae of a living organism, a pulse wave detection section for detecting a pulse wave on the side of peripheral blood vessels appearing with a time lag with respect to the pulse wave on the side of aortae, a pulse wave propagation time measurement section for measuring a pulse wave propagation time based on respective detected outputs from the time interval detection reference point detection section and the pulse wave detection section, an operation device for calculating a pulse wave propagation fluctuation from two measured pulse wave propagation times, a judgment device for judging whether or not the calculated pulse wave propagation time fluctuation exceeds the pulse wave propagation time fluctuation threshold read from the memory, and a control device for controlling the blood pressure measurement device based on an output of the judgment device so that the blood pressure of a subject is measured using the cuff.

A first member is adapted to measure an electrocardiogram of a patient. A second member is adapted to measure a peripheral pulse wave of the patient. A first calculator calculates a pulse wave propagation time (PWTT) and a heart rate (HR) of the patient based on the electrocardiogram and the peripheral pulse wave. A second calculator calculates a cardiac output (CO) of the patient with an equation of CO=(αK·PWTT+βK)·HR, where α, β and K are coefficients inherent to the patient.

A pulse wave is detected in a predetermined location of a living body, and the progressive wave component and reflected wave component are extracted from the pulse wave. The pulse wave propagation time is calculated from the progressive wave component and reflected wave component, and blood pressure is calculated on the basis of this pulse wave propagation time. The use of this method provides blood pressure measuring apparatus capable of continuously measuring blood pressure with a simple method.

The invention relates to a combined variability index testing method of cardiovascular system and the testing device. The testing method comprises the following steps: (1) collecting the electrocardio-signal, the phonocardio-signal and the pulse signal of radial artery; (2) performing analog-to-digital conversion to the three signals to form the signal oscillogram; (3) identifying and extracting the characteristic point of each signal; (4) constructing the time series RR of electrocardio-period, the electromechanical delay time series and the pulse wave propagation time series of the combined variability index; (5) testing the validity of each time series; (6) calculating the heart rate variability, the electromechanical delay variability and the pulse wave propagation time variability; and (7) calculating the combined variability index of angiocarpy AV. The testing device comprises an electrocardio-signal testing module, a phonocardio-signal testing module, radial artery pulse signal testing module, an analog-to-digital converting device and a computer. The invention enables to reflect the physiological and pathological status of the human cardiovascular system well and has the advantages of high discriminating degree and wide clinic application value.

In blood pressure monitoring apparatus which continuously estimates and monitors blood pressure by using the pulse wave propagation time, blood pressure fluctuation can be accurately estimated. If both blood pressure estimated from the pulse wave propagation time and a waveform parameter obtained from the accelerated pulse wave have abnormal values, it is determined that the blood pressure is truly fluctuating, and blood pressure measurement by another method, e.g., blood pressure measurement using a cuff is performed.

The invention discloses a multi-phase fluid oil displacement and pulse unblocking integrated physical simulation experiment device and method. The device mainly comprises a multi-phase fluid generation and storage system, a multi-phase fluid spreading and impulse wave generation system, a reservoir core simulation system and a dynamic experiment data collection system. The multi-phase fluid spreading and impulse wave generation system comprises a multi-phase fluid injection pipeline, a pulse oscillation generation cavity casing, a collision body and a multi-phase fluid output and pulse wave spreading pipeline. The device mainly utilizes difference of gas and liquid elastic modulus to achieve conversion between pulse unblocking / oil displacement and gas (steam) injection functions to simplify the oil displacement / pulse simulation process in different oil reservoir exploitation processes. The experiment can relate to simulation of experiment processes of miscible-phase displacement and gas water alternative oil displacement, reservoir pulse unblocking, thick oil thermal exploitation storage layer steam injection, oil displacement-unblocking and the like. The device is reasonable in design, simple in operation process and capable of effectively simulating the multi-phase fluid oil displacement and pulse unblocking effects.

In blood pressure monitoring apparatus which continuously estimates and monitors blood pressure by using the pulse wave propagation time, blood pressure fluctuation can be accurately estimated. If both blood pressure estimated from the pulse wave propagation time and a waveform parameter obtained from the accelerated pulse wave have abnormal values, it is determined that the blood pressure is truly fluctuating, and blood pressure measurement by another method, e.g., blood pressure measurement using a cuff is performed.

An apparatus for measuring an inferior-and-superior-limb blood-pressure index of a patient, including an inferior-limb blood-pressure measuring device, a superior-limb blood-pressure measuring device, an index determining device for determining the inferior-and-superior-limb blood-pressure index, based on a blood pressure of an inferior limb measured by the inferior-limb blood-pressure measuring device and a blood pressure of a superior limb measured by the superior-limb blood-pressure measuring device, an inferior-limb-pulse-wave-propagation-velocity-related-information, obtaining device which obtains inferior-limb-pulse-wave-propagation-velocity-related information, an upper-half-body-pulse-wave-propagation-velocity-related-information obtaining device which obtains upper-half-body-pulse-wave-propagation-velocity-related information, and an evaluation-information obtaining device for obtaining, based on the inferior-limb-pulse-wave-propagation-velocity-related information and the upper-half-body-pulse-wave-propagation-velocity-related information, evaluation information that is related to evaluation of reliability of the inferior-and superior-limb blood-pressure index.

A pulse wave is detected in a predetermined location of a living body, and the progressive wave component and reflected wave component are extracted from the pulse wave. The pulse wave propagation time is calculated from the progressive wave component and reflected wave component, and blood pressure is calculated on the basis of this pulse wave propagation time. The use of this method provides blood pressure measuring apparatus capable of continuously measuring blood pressure with a simple method.

The invention provides a terminal and a blood pressure measuring method. The terminal comprises a flash lamp, a processor and at least two cameras; a preset distance exists between every two cameras, the flash lamp is used for emitting lamp light with preset frequency under the control of the processor, the cameras are used for collecting photoplethysmography (PPG) signals under the control of the processor, and the PPG signals are the signals which are generated by reflecting the lamp light through the limbs, covering the cameras, of a user and received by the cameras; the processor is used for controlling the flash lamp to emit the lamp light with the preset frequency and controlling the cameras to sequentially collect the PPG signal in the preset frequency, at least one PPG signal collected by each camera is obtained, the pulse-wave propagation velocity is determined according to the PPG signals collected by the cameras, and the measured blood pressure of the user is obtained according to the pulse-wave propagation velocity. The terminal and the blood pressure measuring method can improve the accuracy of the measured blood pressure.

Provided is an arterial stiffness evaluation apparatus using a new arterial stiffness index which serves as an index to evaluate a degree of arterial stiffness, and a program therefor. The arterial stiffness apparatus includes pulse wave detecting means, pulse wave propagation velocity deciding means, blood pressure detecting means, and arterial stiffness index calculating means, in which the arterial stiffness index calculating means executes: a first step of calculating a pulse wave propagation velocity PWVori after pressure calibration and CAVI=ln(Ps / Pd)×PWV2, and deriving a regression equation where PWVori is represented by a quadratic equation of CAVI; a second step of setting the regression equation as an equation representing a arterial stiffness index PWVpcm1; a third step of deriving a regression equation where the PWVori is represented by a linear equation of the PWVpcm1; a fourth step of setting the regression equation as an equation representing an arterial stiffness index PWVpcm2; and a fifth step of obtaining a PWVpcm2 value by substituting a measured value, and the degree of arterial stiffness is evaluated based on the PWVpcm2.

A blood pressure monitoring apparatus which continuously estimates and monitors the blood pressure by using the pulse wave propagation time can accurately estimate the blood pressure. While an estimated blood pressure is continuously calculated by using the pulse wave propagation time, the correlation between the pulse wave propagation time and the interval between feature points contained in two consecutive heart beat waveforms of an electrocardiogram is monitored. If the correlation is reversed, the blood pressure is actually measured, and the estimated blood pressure is corrected on the basis of the difference between the estimated blood pressure and actually measured blood pressure.

An apparatus for diagnosing an angiopathy of a living subject, including a first pulse-wave-propagation-velocity-related-information obtaining device which obtains a first pulse-wave-propagation-velocity-related information that is related to a first velocity at which a first pulse wave propagates through a first interval of the subject, a second pulse-wave-propagation-velocity-related-information obtaining device which obtains, at a substantially same time as a time when the first pulse-wave-propagation-velocity-related-information obtaining device obtains the first pulse-wave-propagation-velocity-related information, a second pulse-wave-propagation-velocity-related information that is related to a second velocity at which a second pulse wave propagates through a second interval of the subject that is different from the first interval, and a comparison-value calculating device for calculating a comparison value based on the first pulse-wave-propagation-velocity-related information and the second pulse-wave-propagation-velocity-related information.

A CPU of a blood pressure information measurement device calculates blood pressure from a change in internal pressure of an air bladder used to measure the blood pressure. AI (augmentation index) and Tr (traveling time to reflected wave) are calculated from a pulse wave waveform. A path difference calculation unit of the CPU stores a correction equation to correct a pulse wave propagation distance that is stored in advance, and, by substituting the calculated blood pressure value, AI and the like into the correction equation, corrects the pulse wave propagation distance stored in advance and approximates the pulse wave propagation distance stored in advance to an actual pulse wave propagation distance. A PWV (pulse wave velocity) calculation unit calculates the PWV using the corrected distance.

The invention relates to the field of biomedical monitoring, in particular to a non-contact blood pressure measuring method which does not restrain a human subject. According to the non-contact bloodpressure measuring method, a single biomedical radar is adopted to be aligned with the abdomen and the back of the human subject, then the human subject is required to hold breath, an aorta pulse wavewaveform signal collected during breath holding is recorded, feature extraction is conducted through an EMD algorithm, all feature points of the aorta pulse wave waveform signal are obtained, and themapping relation of each feature point and the time period of a pulse wave is determined; according to the mapping relation, the pulse wave propagation time which corresponds to the aorta pulse wavewaveform signal and is obtained by the biomedical radar is obtained; and a corresponding blood pressure value can be obtained through the pulse wave propagation time. Compared with a traditional bloodpressure value measuring method, only a single radio frequency senor is needed in the measuring method, precision is higher, and the obvious advantages that instrument contact is not needed and the human subject is not retrained are achieved. The non-contact blood pressure measuring method is effective and feasible, the property is reliable, and the blood pressure value can be obtained accurately.

In the present disclosures, the CPU (40) of a sphygmomanometer (1) calculates blood pressure from the changes in the internal pressure of an air sac (13B) that is for measurement. Also, AI and Tr are calculated from the pulse waveform. The path difference calculation unit (405) of the CPU (40) records a correction formula for correcting a pre-recorded pulse wave propagation distance, and by substituting the calculated blood pressure values, AI, or the like into the correction formula, corrects the pre-recorded pulse wave propagation distance to approach the actual pulse wave propagation distance. A PWV calculation unit (406) calculates the PWV using said distance.

The invention discloses a measuring method of finger tip blood flow rate based on an accelerated pulse wave and a measuring instrument thereof. The instrument comprises a volume pulse wave acquisition module, a signal conditioning module, an operation processing module, an external mass memory module, a USB (Universal Serial Bus) communication module, a waveform and result display module. The measuring method comprises the following steps: during measuring, detecting a human finger tip pulse beating signal a volume pulse wave sensor, after passing through the signal conditioning module, converting the human finger tip pulse beating signal into a digital signal by using operation processing module, storing the digital signal in the external mass memory module, carrying out twice differential processing and filtering processing on a volume pulse wave so as to obtain a smoothing quadratic differential waveform, namely an accelerated pulse wave required by a system; extracting out pulse wave propagation time from the accelerated pulse wave, and establishing a functional relation between the propagation time and human blood pressure so as to determine blood flow rate. The measuring method of the finger tip blood flow rate based on the accelerated pulse wave and the measuring instrument thereof realize non-invasive, convenient and fast, accurate and reliable measurement on the finger tip blood flow rate; the measuring instrument requires few input signals; and the relation between a input signal and a measuring result is stable.

A first member is adapted to measure an electrocardiogram of a patient. A second member is adapted to measure a peripheral pulse wave of the patient. A first calculator calculates a pulse wave propagation time (PWTT) and a heart rate (HR) of the patient based on the electrocardiogram and the peripheral pulse wave. A second calculator calculates a cardiac output (CO) of the patient with an equation of CO=(αK·PWTT+βK)·HR, where α, β and K are coefficients inherent to the patient.

A biological information measurement apparatus includes an irradiation unit configured to irradiate a living body with light or sound waves as measurement waves; a detection unit configured to detect the measurement waves having passed through the inside of the living body; and a computational unit configured to obtain a change over time in blood flow rate and a change over time in blood vessel cross-sectional area based on a detection result from the detection unit, and to obtain a pulse wave propagation velocity from the change over time in blood flow rate or the change over time in blood vessel cross-sectional area.

The invention discloses a method and system for measuring pulse wave propagation speed. The method includes: measuring and recording artery pulse wave of a certain part of a human body by using Doppler ultrasound to obtain a Doppler ultrasonic signal strength-time map, measuring a time difference Delta t between a main peak descending branch end and a re-pulse wave start on the time map, calculating an artery total length L from a main artery root to a pulse wave measurement site according to the height H of a testee, pulse wave propagation speed S of the testee on this artery measurement section being equal to a ratio of L to Delta t. The invention provides a novel method of measuring artery pulse wave speed by using the method of measuring pulse wave signals using Doppler ultrasound, in the hope of providing theoretical and technical basis for further clinical application. In addition, the method is simple, operating is convenient, measuring accuracy is higher, and clinical level is partly increased.

The invention relates to a method for measuring a local pulse wave propagation speed of a carotid blood vessel, which comprises the following steps: a step 1 of designing an ultrafast comb-tooth-shaped focus beam transmitting and receiving sequence and simultaneously acquiring a plurality of points of radio frequency echo signals in the long axis direction of the carotid blood vessel; a step 2 of identifying and tracking an echo signal of front and rear walls of the vessel in each scanning line after carrying out filtering preprocessing on a plurality of focus beam echo signals, which are simultaneously received, in the long axis direction of the carotid blood vessel; a step 3 of respectively carrying out one-dimensional self-correlation phase shifting estimation on adjacent frames of echo signals of the front and rear walls of the vessel in each scanning line to obtain a corresponding phase shifting speed waveform and then obtaining a corresponding phase shifting waveform of the vessel wall along with variation of a cardiac cycle in each scanning line; a step 4 of calculating relative time delay between the phase shifting waveforms of the vessel wall in the adjacent scanning lines and carrying out linear fitting on the time delay so as to obtain a reciprocal of a slope, i.e. the estimated local pulse wave propagation speed. The method provides new basis for early detection of the atherosclerosis.

A pulse wave propagation time measurement device including a first signal processor section that filters an electrocardiographic signal detected by an electrocardiographic sensor, a second signal processor section that filters a photoelectric pulse wave signal detected by a photoelectric pulse wave sensor, peak detectors respectively that detect peaks of the electrocardiographic signal and the photoelectric pulse wave signal, delay time obtaining sections respectively that obtain a delay time of the electrocardiographic signal and of the photoelectric pulse wave signal, peak correctors respectively that correct the peaks of the electrocardiographic signal and the photoelectric pulse wave signal based on the delay time of the electrocardiographic signal and the photoelectric pulse wave signal, and a pulse wave propagation time measurement section that obtains a pulse wave propagation time from a time difference between the corrected peaks of the electrocardiographic signal and the photoelectric pulse wave signal.

Provided is a pulse wave propagation detection system including electrocardiographic signal detection means, and eyeground image detection means for detecting an eyeground image in synchronization with an electrocardiographic signal detected through the detection means, which system further includes means for correlating a change in the diameter of an eyeground vein—which diameter is measured, at the optic papilla, by use of an eyeground image synchronized with an arbitrary electrocardiographic signal—with the state of pulse wave propagation through an intracerebral blood vessel or with the state of sclerosis of a capillary artery. Provision of the pulse wave propagation detection system; i.e., means for conveniently and accurately identifying the state of blood flow in the brain or the state of sclerosis of a capillary artery, enables prevention of adverse effects of, for example, excessive drop in blood pressure.

An arteriostenosis diagnosing apparatus which measures an ankle blood pressure at an ankle 12 of a patient and a brachium blood pressure at a brachium 14, so that the measured ankle and brachium blood pressure values are used to calculate an ankle and brachium blood pressure index ABI, and additionally measures a first pulse wave propagation velocity PWV1 with respect to the ankle 12 as a first measuring point and the brachium 14 as a second measuring point, and a second pulse wave propagation velocity PWV2 with respect to the patient's heart and the brachium 14. The arteriostenosis diagnosing apparatus includes an arteriostenosis judging device 100 which judges, even if the index ABI may fall in a prescribed normal range or a prescribed alert range and the first velocity PWV1 falls in a prescribed normal range, that there is a possibility that an inferior limb including the ankle 12 at which the ankle blood pressure has been measured, may have arteriostenosis, if the second velocity PWV2 falls in a prescribed abnormal range.

In the measurement device, the blood pressure of the upper arm and the blood pressure of the lower limb are measured using cuffs attached to the upper arm and the lower limb (ankle), respectively. The pulse wave of the upper arm and the pulse wave of the lower limb are measured in synchronization using such cuffs. The upper arm-lower limb pulse wave propagation velocity (baPWV) is calculated based on the appearance time difference of the two pulse waves. The upper arm pulse wave propagation velocity (upper arm PWV) is calculated based on the appearance time difference of the ejection wave and the reflection wave in the upper arm pulse wave. If the values of such propagation velocities are different, a warning is issued.

The invention discloses a measuring method and a measuring device for pulse wave propagation time. The method comprises: synchronously collecting a pulse wave signal and an electrocardiogram signal ofa measured person, extracting characteristic points of the pulse wave signal and the electrocardiogram signal, and calculates a pulse conduction time PAT. The pre-ejection PEP was calculated according to the electrocardiogram signal. The pulse wave propagation time (PTT) is obtained by subtracting the pre-ejection PEP from the calculated pulse propagation time (PAT). The invention eliminates theinfluence of the pre-ejection period and improves the measurement accuracy of the pulse wave propagation time PTT.

A biological-information detecting apparatus includes a first blood-flow measuring device provided at a seat surface of a seat, the first blood-flow measuring device measuring a condition of a blood flow of a popliteal artery of a measurement subject seated in the seat, a second blood-flow measuring device provided at a back of the seat, the second blood-flow measuring device measuring a condition of a blood flow of a thoracic aorta of the measurement subject, and a blood-pressure calculation device determining a pulse-wave propagation velocity and a degree of arteriosclerosis from blood flow data acquired by the first blood-flow measuring device and blood flow data acquired by the second blood-flow measuring device and calculating blood pressures of the popliteal artery and the thoracic aorta of the measurement subject based on the pulse-wave propagation velocity and the degree of arteriosclerosis.

The blood pressure monitoring apparatus and method are disclosed that can monitor a blood pressure of a subject using an electrocardiogram signal, a pulse wave signal and a body characteristic information of the subject, wherein the electrocardiogram signal and the pulse wave signal of the subject are monitored to remove a noise signal generated from monitoring of the pulse wave signal, allowing monitoring a precise blood pressure of the subject, and calculating the pulse wave analysis information using the monitored pulse wave signal, and using the electrocardiogram signal and the pulse wave signal to calculate a pulse transit time (PPT), and plugging a calculated pulse wave propagation time, pulse wave analysis information and body characteristic information of the subject into a predetermined regression equation to monitor the blood pressure.