102 results about "Arterial stiffness" patented technology

A system that continuously monitors cardiovascular health using an electrocardiography (ECG) source synchronized to an optical (PPG) source, without requiring invasive techniques or ongoing, large-scale external scanning procedures. The system includes an ECG signal source with electrodes contacting the skin, which generates a first set of information, and a watch-like device, worn on a limb such as an arm or a wrist, having a reflectance-based PPG signal source that generates a second set of information. Together with a processing module, housed within the watch-like device and configured to receive and process the first and second sets of information, from which the time differential of the heart beat pulmonary pressure wave can be calculated, continuous data related to cardiovascular health markers such as arterial stiffness can be determined. Automated heart rate calibration of the reflectance-based PPG sensor can also be achieved.

A system that continuously monitors cardiovascular health using an electrocardiography (ECG) source synchronized to an optical (PPG) source, without requiring invasive techniques or ongoing, large-scale external scanning procedures. The system includes an ECG signal source with electrodes contacting the skin, which generates a first set of information, and a mobile device having a camera which acts as a PPG signal source that generates a second set of information. Together with the mobile device's processor, configured to receive and process the first and second sets of information, from which the time differential of the heart beat pulmonary pressure wave can be calculated, continuous data related to cardiovascular health markers such as arterial stiffness can be determined. Variations of the ECG source may include a chest strap, a plug-in adaptor for the mobile device, or electrodes built into the mobile device.

The invention relates to a method and apparatus for detecting the condition of blood vessel system function, which is capable of non-invasive synchronously detecting the heart function, the carotid sclerosis, and the level of blood viscosity. The invention is characterized in that: a piezoresistance type sensor is positioned at neck for pressurizing; a heart sound signal piezoelectric sensor is positioned on the part of heart; a plurality of detecting electrodes for the electrocardiogram signals are arranged on the right hand wrist and lower parts of ankles; the cuffs of four limbs are arranged on upper arms and upper parts of ankles respectively; the inflation or deflation of cuffs is controlled by computer; the synchronous acquisition of the pulse signals of carotid, heart sound signals,electrocardiogram signals, pulse signals of carotids on four limbs by muilti-channel synchronous A / D die exchange module are converted; the converted signals are transmitted to a data processing module for data processing, and obtaining the heart function, the carotid sclerosis and the level of blood viscosity and other parameters.

The capsule for treating asthma, pulmonary emphysema and SARS is developed based on the principle that the Chinese medicine and the Western medicine are complementary and synergistic, and compounded with several kinds of Chinese medicines and Western medicines. It can kill bacteria, resist virus, eliminate circulating disturbance and regulate immunity, and suitable for various people in different disease stages. It has high and stable curative effect. In addition, it has also certain treating effect on hypertension, angiosclerosis, wind-wetness Bi syndrome, etc.

Provided is an arterial stiffness evaluation apparatus using a new arterial stiffness index which serves as an index to evaluate a degree of arterial stiffness, and a program therefor. The arterial stiffness apparatus includes pulse wave detecting means, pulse wave propagation velocity deciding means, blood pressure detecting means, and arterial stiffness index calculating means, in which the arterial stiffness index calculating means executes: a first step of calculating a pulse wave propagation velocity PWVori after pressure calibration and CAVI=ln(Ps / Pd)×PWV2, and deriving a regression equation where PWVori is represented by a quadratic equation of CAVI; a second step of setting the regression equation as an equation representing a arterial stiffness index PWVpcm1; a third step of deriving a regression equation where the PWVori is represented by a linear equation of the PWVpcm1; a fourth step of setting the regression equation as an equation representing an arterial stiffness index PWVpcm2; and a fifth step of obtaining a PWVpcm2 value by substituting a measured value, and the degree of arterial stiffness is evaluated based on the PWVpcm2.

The invention discloses an application of sichuan lovage rhizome oil by supercritical CO2 extraction method in pharmacy, which can be used for treating vascular nerve cephalalgia, cerebral thrombus, cerebrovascular angiosclerosis, coronary heart diseases, angina pectoris, hypertension, or asomnia, or common cold, or women's dysmenorrheal.

Devices and methods of use identification, treatment, and / or management of heart failure and / or associated conditions. Methods may include providing a baroreflex therapy system including a blood pressure sensor and a heart rate sensor, providing an implantable measurement device proximate a blood vessel of a patient, the implantable measurement device including an electrode, providing a control system coupled to the baroreflex therapy system and the implantable measurement device, the control system programmed to automatically determine an impedance of the blood vessel with the implantable measurement device over a time period of at least one cardiac cycle, determine arterial stiffness of the blood vessel based on the impedance, determine blood pressure and heart rate, and activate, deactivate or otherwise modulate the baroreflex therapy system to deliver a baroreflex therapy based on the blood pressure, heart rate and arterial stiffness.

In some embodiments, a method and / or device are disclosed for measuring a pressure drop over a portion of a body lumen. Optionally, the pressure drop for two different flow conditions may be used to find the stiffness of the lumen. In some embodiments the device may be calibrated, for example by correcting for distortion, for example the common mode pressure distortion. Pressure drop and or stiffness measures may be used to evaluate a treatment procedure and / or a stenosis.

A CPU of a blood pressure information measurement device calculates blood pressure from a change in internal pressure of an air bladder used to measure the blood pressure. AI (augmentation index) and Tr (traveling time to reflected wave) are calculated from a pulse wave waveform. A path difference calculation unit of the CPU stores a correction equation to correct a pulse wave propagation distance that is stored in advance, and, by substituting the calculated blood pressure value, AI and the like into the correction equation, corrects the pulse wave propagation distance stored in advance and approximates the pulse wave propagation distance stored in advance to an actual pulse wave propagation distance. A PWV (pulse wave velocity) calculation unit calculates the PWV using the corrected distance.

When the heart beats, ventricular ejection is performed to genertate a pulse wave which is transmitted to the whole body at a certain velocity. The pulse wave velocity (PWV) refers to the velocity of the pulse wave which is transmitted from one position of an artery to another position of the artery. The parameter is always used in the diagnosis of vascular diseases and particularly used to judge the degree of vascular sclerosis. When the degree of vascular sclerosis increases, the arterial compliance is reduced and the PWV is increased. The current noninvasive measurement method of the PWV is to divide the length of a blood vessel by the conduction time of the pulse wave in the blood vessel, thus how to correctly identify the initial beating point becomes a main problem for calculating the PWV. The computation method of the invention utilizes wavelet transform to extract the initial beating point of the pulse wave. The method comprises the following steps: the multiresolution decomposition method is utilized to decompose the pulse wave, the a'trous algorithm is used to ensure that the decomposition result has the same length of the original signal and the detailed and general information of the pulse wave can be obtained; and the result of wavelet transform is compared with the pulse wave, and an obvious peak appears at the initial beating point of the pulse wave in the decomposition result of the pulse wave, thus the position of the initial beating point can be obtained through the comparison of the decomposition result and the pulse wave.

A circulatory function measurement device that accurately measures a subject's circulatory function. A pulse wave accumulated value calculation unit calculates a pulse wave accumulated value by accumulating the amplitude values of pulse waves in chorological order as the compressing pressure changes. A blood vessel hardness measurement unit measures blood vessel hardness based on the relationship between the calculated pulse wave accumulated value and the compressing pressure.

The invention relates to a blood pressure microsensor comprising means of holding and positioning a chip of piezoresistive material (10) on the inside face of a practitioner's finger, the chip dimensions being smaller than the diameter of the artery in which the pressure is to be measured, the microsensor also comprising means of transmitting the electrical signal output (12) by the piezoresistive chip in response to a pressure applied to the chip (10). It also relates to an arterial stiffness measurement apparatus using such microsensors.

Devices and methods of use identification, treatment, and / or management of heart failure and / or associated conditions. Methods may include providing a baroreflex therapy system including a blood pressure sensor and a heart rate sensor, providing an implantable measurement device proximate a blood vessel of a patient, the implantable measurement device including an electrode, providing a control system coupled to the baroreflex therapy system and the implantable measurement device, the control system programmed to automatically determine an impedance of the blood vessel with the implantable measurement device over a time period of at least one cardiac cycle, determine arterial stiffness of the blood vessel based on the impedance, determine blood pressure and heart rate, and activate, deactivate or otherwise modulate the baroreflex therapy system to deliver a baroreflex therapy based on the blood pressure, heart rate and arterial stiffness.

Nebivolol has been shown to be beneficial in the treatment of cardiovascular diseases such hypertension, congestive heart failure, arterial stiffness and endothelial dysfunction. The present invention features a pharmaceutical composition comprising nebivolol and at least one other active agent, wherein the at least one other active agent is a cardiovascular agent.

Nebivolol has been shown to be beneficial in the treatment of cardiovascular diseases such hypertension, congestive heart failure, arterial stiffness and endothelial dysfunction. The present invention features a pharmaceutical composition comprising nebivolol and at least one other active agent, wherein the at least one other active agent is a cardiovascular agent.

A method for evaluating the cardiovascular damage degree of hypertension patient on the basis of artificial nerve network features that after 10 parameters including systolic pressure, diastolic pressure, body weight index, ejection period, pulse output, cardiac output, etc are input, the cardiovascular damage degree can be calculated out by use of the nerve network equation Y=f2 (W2f1(W1x+B1)+B2). Its advantage is high correctness.

The circulatory dynamics measurement apparatus comprises: a blood pressure-computing unit, which calculates the maximum blood pressure value (SYS); a vascular sclerosis-computing unit, which calculates the vascular sclerosis index (VSI); and a display unit for displaying a graph having a horizontal axis that represents the maximum blood pressure and a vertical axis that represents the vascular sclerosis index. The display unit displays the position determined by the calculated maximum blood pressure value and the calculated vascular sclerosis index in the plotting area of the graph.

The invention relates to beverage dissolved with phytosterol. The beverage per 100ml contains 10-120mg of phytosterol. The beverage is prepared by the steps of production of a semi-finished beverage product, phytosterol dissolving and production of a finished product. The phytosterol is insoluble in water and is difficultly dissolved in water, and the content of phytosterol in common beverage is extremely low; and at present, patients suffered from cardia-cerebrovascular diseases, angiosclerosis, cholelithiasis and tumor due to foods with high fat and cholesterol contents can be daily on the increase at present; Chinese medical association notes that patients with abnormal blood lipid need eat 2g of phytosterol or 3.4g of phytosterol ester everyday, phytosterol can reduce cholesterol, repair tissues and inhibit tumors and is a new resource food or a health food supplement recognized by China, Europe, America, Japan and the like; phytosterol is dissolved in alcohol, is combined with beverage, and has synergistic interaction with a function of promoting blood circulation by removing blood stasis; the beverage can reduce cholesterol, is antivirus, oxidation-resistant and anti-aging, can diminish inflammation, achieves immune adjustment and the beautifying effect and inhibits blood platelet aggregation when being drunk in moderation; the beverage is beneficial to health of patients suffered from diseases such as cardia-cerebrovascular disease, gall stone, tumor and prostate disease when being drunk moderately.

A CPU of a blood pressure information measurement device calculates blood pressure from a change in internal pressure of an air bladder used to measure the blood pressure. AI (augmentation index) and Tr (traveling time to reflected wave) are calculated from a pulse wave waveform. A path difference calculation unit of the CPU stores a correction equation to correct a pulse wave propagation distance that is stored in advance, and, by substituting the calculated blood pressure value, AI and the like into the correction equation, corrects the pulse wave propagation distance stored in advance and approximates the pulse wave propagation distance stored in advance to an actual pulse wave propagation distance. A PWV (pulse wave velocity) calculation unit calculates the PWV using the corrected distance.

The invention provides a health food for preventing and treating cardiac and cerebral thrombotic diseases and relates to the field of health foods. The health food is prepared from 2-4 parts by weight of garlics, 2-4 parts by weight of yolks, 3-4 parts by weight of poria cocos, 1-3 parts by weight of ginseng, 3-4 parts by weight of ganoderma lucidum, 90-100 parts by weight of natto, 3-4 parts by weight of pseudo-ginseng and 2-3 parts by weight of Chinese yam. The health food has effects of softening and dredging blood vessels, reducing blood fat and blood pressure, improving a cell regeneration capability and preventing and treating arteriosclerosis, contains components such as soybean polypeptide and phosphatidylcholine bilayer with functions of reducing cholesterol, softening blood vessels and preventing and treating blood vessel hardening, contains streptokinase with functions of dissolving thrombus and fat embolus and reducing blood fat and has functions of preventing and treating hypertension, myocardial infarction and cerebral hemorrhage.

The invention relates to a kind of measuring apparatus and methods, which is contacting with the arterial vessel surface nearby the life body by transducer, and measuring the followings through life body vessel: blood pressure, pulse frequency, cardiac frequency, blood flow volume, blood drag force and vascular sclerosis parameter. It can also be applied in hand-held communication apparatus, or personal digital assistant, comprising: measuring probe to measure the life body vascular system physical characteristic parameter; ways to judge whether the transducer can detect the diastolization pressure; ways to calculate and ascertain diastolization pressure by the detected waveshape if the transducer hasn't detected it; and pressure or displacement transducer. The invention makes the blood pressure measuring device more simple, smaller and more convenient to use.

The invention belongs to the field of bio-pharmaceuticals, relates to a novel application of a novel inhibitor large-conductance calcium-activated potassium channel (also called a BK channel) opener NS1619 influencing a process of establishing a vascular smooth muscle cell calcification model, specifically relates to an application of the NS1619 used for establishing the vascular smooth muscle cell calcification model, and in particular relates to a novel application of the NS1619 used for preparing drugs for inhibiting vascular smooth muscle cell calcification. Cell experiment results prove that the NS1619 has effects of inhibiting vascular smooth muscle cell calcification, including an effect of inhibiting Ca<2+> deposition in the calcification process, an effect of inhibiting molecular expression of a calcification marker molecule and an effect of inhibiting formation of calcium nodules. The NS1619 can be further used for preparing drugs for treating diseases related to vascular sclerosis and smooth muscle contraction or relaxation dysfunction, including treatment of atherosclerosis, asthma, cerebral ischemic injury, uroschesis and other smooth muscle dysfunction related diseases.

Nebivolol has been shown to be beneficial in the treatment of cardiovascular diseases such as, but not limited to, hypertension, congestive heart failure, arterial stiffness and endothelial dysfunction. The present invention relates to methods for treating and / or preventing cardiovascular disorders in persons of Hispanic descent, particularly Mexican Americans, using compositions comprising nebivolol.

A blood pressure monitor and a method for detecting vascular sclerosis thereof are revealed. The blood pressure monitor includes a cuff, an air pump, an air escape valve, a pressure sensor, a processing circuit, and an arithmetic circuit. The cuff is arranged at a body to be detected and the air pump inflates the cuff. The air escape valve is for releasing air from the cuff while the pressure sensor arranged at the cuff measures a cuff pressure to generate an analog pressure sensing signal. The processing circuit processes the pressure sensing analog signal and generates a digital pressure sensing signal. Then a systolic pressure and a diastolic pressure of the detected body are calculated according to the digital pressure sensing signal. The degree of blood vessel hardening is checked according to a systolic area of the calculated systolic pressure and a diastolic area of the calculated diastolic pressure.

The invention relates to the field of medicinal health, and particularly relates to a pharmaceutical composition which is prepared by combination of polyunsaturated fatty acids and theaflavin and has an effect of lowering blood fat. The polyunsaturated fatty acids and theaflavin used as main effective ingredients are combined with beneficial effects of the polyunsaturated fatty acids and the theaflavin in the aspect of lowering blood fat. Tests prove that the composition can be used for remarkably reducing the blood-fat level and ambulatory arterial stiffness index of an experimental animal and effectively controlling the blood-fat level. The composition is completely prepared from natural animal and plant ingredients which are used as effective ingredients, has the advantages of wide material source, low production cost, no dependence after long-time taking, no toxic or side effect and the like, is safe and effective, and is suitable for large-scale popularization and application.

This document describes ways in which to alter physiological signals to address corrupt, noisy, or otherwise faulty data. By so doing, accuracy and robustness in sensing and assessing a patient's cardiovascular health can be improved. These improved assessments permit better measures of health, such as relevant hemodynamics understood by heart rates, heart rate variability, cardiac arrhythmias, blood pressures, pulse-wave velocities, arterial stiffness, cardiac valve timing, thoracic fluids, ballistocardiogram force, photo-plethysmograms, blood oxygenation, and pressure-volume loops.

The invention relates to a Chinese traditional medicine preparation, particularly a preparation prepared from Chinese medicinal herbs for treating coronary heart disease. The preparation contains fourteen kinds of Chinese medicinal herbs such as prepared rehmannia root, pilose asiabell root, milk vetch, Chinese yam, medical dogwood, parched spine date seed, best poria, root of red rooted salvia, ophiopogon root, etc. The preparation is obtained by repeated experiments of the inventor based on a patrimonial secret recipe in combination with his / her clinical experience for years; and the preparation has particular therapeutic effect to myocardial ischemia, angina pectoris, palpitation, oppressed feeling in chest, insomnia and dreamful sleep, cardiovascular and cerebrovascular sclerosis caused by refractory coronary heart disease. The preparation has the advantages of scientific formulation, rapid therapeutic effect, short treatment period, high cure rate and low cost, and is effective in invigorating the liver and the kidney, relieving mental stress, promoting blood circulation and eliminating blood stasis, promoting circulation of qi to relieve pain, consolidating the constitution to restore the vitality, balancing yin and yang, etc.