Oral sedative for children

Abstract

The invention discloses an oral sedative for children. The oral sedative comprises the following components: simple syrup, a chloral hydrate solution with the mass concentration of 10%-20%, and a glucose solution, containing sodium citrate, with the mass concentration of 5%-10% according to the volume proportion of the (1-2):2:1, wherein the mass concentration of the glucose solution dissolving sodium citrate is 5%-10%; the main simple syrup component is the simple syrup of cane sugar, and the mixed oral sedative is a weak alkaline solution with the pH value of 7-8. According to the sedative formula of the application, (1) the taste of the conventional chloral hydrate is improved, and the conflict reaction when the sedative is taken by an infant patient is reduced; (2) the effect-taking time of the oral chloral hydrate sedative is shortened, so that the sedative can be absorbed by small intestines relatively easily, the bioavailability is improved, the stimulation on gastrointestinal tracts is reduced, and nausea and vomiting are reduced.

Description

technical field [0001] The invention belongs to the technical field of pharmaceutical preparations, and more precisely relates to a sedative pharmaceutical preparation, in particular to an oral sedative for infants and young children. Background technique [0002] Sedative drugs are mainly used in the treatment of mental diseases. Their main effect is to relieve people's depression and anxiety, and to treat inability to sleep caused by mental stress. Commonly used sedative drugs include phenobarbital, meproton, chlordiazepoxide, and diazepam. However, the use of these drugs is strictly restricted to pregnant women and children. Even people with normal health who take stable sedative drugs for a long time will have side effects: drowsiness, inability to concentrate, unresponsiveness, memory loss, dizziness, etc. [0003] For children with mental stress, especially children who are examined in general pediatrics, blood tests and other tests are usually required to diagnose th...

AI Technical Summary

Problems solved by technology

[0005] But chloral hydrate mouthfeel is very poor, has very strong bitter taste and pungent taste, and infants and young children can appear violent crying resistance when oral; It is easy to vomit after being stimulated, which leads to vomiting of the medicine that has been taken, and because the amount of medicine vomited out cannot be estimated, if it is taken orally again, it may lead to excessive drug intake and poisoning, which will cause various inspections of the disease to be unable to be carried out; and if The method of enema administration to sick children must be fixed by compulsory measures before the liquid can be poured in. In the process of forcing the children to act, it is easy to cause physical harm to the children and affect the treatment.

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