Lycopene tablet for protecting liver and relieving alcohol effect, and preparation method thereof

A technology of lycopene tablets and lycopene oil, which is applied in the field of health care products, can solve the problems of not being able to know the content of lycopene, and the inability to absorb lycopene, so as to relieve the mood after drinking, improve bioavailability, and prevent stagnation. drunk effect

Inactive Publication Date: 2015-07-29
南京远见生物工程有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The active ingredient lycopene has not been purified, and it is used as medicine in the form of autumn olive powder. The public cannot know the content of lycopene in it, and after taking it, it involves the process of lycopene being dissolved from the autumn olive extract. Lycopene cannot be directly absorbed by the body

Method used

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  • Lycopene tablet for protecting liver and relieving alcohol effect, and preparation method thereof
  • Lycopene tablet for protecting liver and relieving alcohol effect, and preparation method thereof
  • Lycopene tablet for protecting liver and relieving alcohol effect, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Example 1 Liver-protecting and hangover-relieving tablets

[0022] 1000 Tablets Formula:

[0023] Lycopene oil (lycopene content 5%), 120g, accounting for 24% by mass,

[0024] β-cyclodextrin, 195g, accounting for 39% by mass,

[0025] Microcrystalline cellulose, 60g, accounts for 12% by mass,

[0026] Pregelatinized starch, 100g, accounts for 20% by mass,

[0027] Sodium carboxymethyl starch, 5g, accounting for 1% by mass,

[0028] Magnesium stearate, 2.5g, accounting for 0.5% by mass,

[0029] Silicon dioxide, 2.5g, accounting for 0.5% by mass,

[0030] Coating powder, 15g, accounts for 3% by mass. (Opadry II, Shanghai Colorcon Coating Technology Co., Ltd.)

[0031] Put the prescribed amount of β-cyclodextrin, microcrystalline cellulose, and pregelatinized starch in a mixer and mix for 5 minutes, add lycopene oil, stir at high speed for 10 minutes, and transfer the above materials to the wet granulation mechanism for 20 mesh granules, 60 Dry in a vacuum oven f...

Embodiment 2

[0032] Example 2 Liver-protecting and hangover-relieving tablets

[0033] 1000 Tablets Formula:

[0034] Lycopene oil (lycopene content 7.5%), 120g, accounting for 24% by mass

[0035] β-cyclodextrin, 195g, accounting for 39% by mass

[0036] Microcrystalline cellulose, 60g, accounts for 12% by mass

[0037] Pregelatinized starch, 100g, accounting for 20% by mass

[0038] Sodium carboxymethyl starch, 5g, accounting for 1% by mass

[0039] Magnesium stearate, 2.5g, accounting for 0.5% by mass

[0040] Silicon dioxide, 2.5g, accounting for 0.5% by mass

[0041] Coating powder, 15g, accounts for 3% by mass. (Opadry II, Shanghai Colorcon Coating Technology Co., Ltd.)

[0042] Put the prescribed amount of β-cyclodextrin, microcrystalline cellulose, and pregelatinized starch in a mixer and mix for 5 minutes, add lycopene oil, stir at high speed for 10 minutes, and transfer the above materials to the wet granulation mechanism for 20 mesh granules, 60 Dry in a vacuum oven for ...

Embodiment 3

[0043] Example 3 Liver-protecting and hangover-relieving tablets

[0044] Made into 1000 pieces

[0045] Lycopene oil (lycopene content 10%), 120g, accounting for 24% by mass

[0046] β-cyclodextrin, 195g, accounting for 39% by mass

[0047] Microcrystalline cellulose, 60g, accounts for 12% by mass

[0048] Pregelatinized starch, 100g, accounting for 20% by mass

[0049] Sodium carboxymethyl starch, 5g, accounting for 1% by mass

[0050] Magnesium stearate, 2.5g, accounting for 0.5% by mass

[0051] Silicon dioxide, 2.5g, accounting for 0.5% by mass

[0052] Coating powder, 15g, accounting for 3% by mass (Opadry II, Shanghai Colorcon Coating Technology Co., Ltd.)

[0053] Put the prescribed amount of β-cyclodextrin, microcrystalline cellulose, and pregelatinized starch in a mixer and mix for 5 minutes, add lycopene oil, stir at high speed for 10 minutes, and transfer the above materials to the wet granulation mechanism for 20 mesh granules, 60 Dry in a vacuum oven for 60 ...

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PUM

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Abstract

The invention discloses a lycopene tablet for protecting liver and relieving alcohol effect, and a preparation method thereof. The lycopene tablet comprises 24wt% of lycopene oil, 39wt% of beta-cyclodextrin, 12wt% of microcrystalline cellulose, 20wt% of pregelatinized starch, 1wt% of sodium carboxymethyl starch, 0.5wt% of magnesium stearate, 0.5wt% of silica and 3wt% of coating powder. The lycopene oil is creatively adopted as a main medicine and an adhesive, specific auxiliary materials are screened, and wet granulation is carried out to prepare the tablet, so the defects of present capsule preparations are overcome, and the gap in lycopene preparations is filled. The lycopene tablet can enhance immunity and reduce damages of alcohol to liver, can be orally administrated before or after drinking to make effective components rapidly disassimilate alcohol in vivo, promotes detoxification and toxin expelling of the liver, reduces damages of the alcohol to all systems of human body, and has sobering, mind clearing and drunk prevention effects.

Description

technical field [0001] The invention belongs to the field of health products, and relates to a lycopene tablet for protecting the liver and relieving alcohol and a preparation method thereof. Background technique [0002] The liver is the largest glandular organ with the most functions in the human body. It participates in the processes of digestion, metabolism, excretion, detoxification and immunity in the body, among which the metabolic function is the most important. The liver is an important material metabolism organ, which plays an important role in the absorption, storage, biotransformation, secretion and excretion of carbohydrates, lipids, proteins, vitamins, hormones, bile and other substances; it has an important role in detoxification and phagocytosis Function, protect the normal internal environment of the human body and defend against the invasion of foreign pathogenic microorganisms; have an important blood regulation function, participate in the hematopoietic p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/30A61K31/01A23L1/09A23P1/02A61P1/16A61P39/02
Inventor 董祥玉孙红日孙晓东
Owner 南京远见生物工程有限公司
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