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A kind of traditional Chinese medicine granule preparation for treating gout and preparation method thereof

A technology of traditional Chinese medicine granules and preparations, which can be used in pharmaceutical formulations, medical preparations containing active ingredients, medical raw materials derived from arthropods, etc., can solve the problems of inability to fully exert the medicinal value of traditional Chinese medicines, unfavorable full absorption, and waste of resources, etc. To achieve the effect of improving utilization value, process stability and low cost

Active Publication Date: 2017-10-31
GUANGDONG ROC MEDICINAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Aiming at the current traditional Chinese medicine taking method and the leftover medicine dregs in the extraction and separation process, a lot of waste is caused. Simply drinking decocted Chinese medicine cannot give full play to the medicinal value of Chinese medicine, and it is not conducive to the full absorption of the human body, resulting in resources waste of
At present, there are basically no subsidiary products developed for traditional Chinese medicine dregs in the market. Therefore, it is particularly important to develop a method that can use traditional Chinese medicine dregs to ferment and prepare traditional Chinese medicine granules to make better use of Chinese herbal medicine resources.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] Embodiment 1, the preparation method of the Chinese medicine granule preparation that the present invention is used for the treatment of gout

[0056] (1) extract

[0057] Mix 5 kg of the Chinese medicine composition, pulverize it, add 70% ethanol which is 10 times the total dry weight of the medicinal materials, reflux extraction twice, each time for 2 hours, filter, combine the filtrates and concentrate to remove ethanol, and obtain the Chinese medicine extract, set aside, filter residue Dried at 60°C, pulverized, and set aside; the traditional Chinese medicine composition comprises 7 parts of Polygonum cuspidatum, 6 parts of Plantain, 6 parts of Ligustrum lucidum and 3 parts of honeycomb.

[0058] (2) Saccharification

[0059] a. Add water twice the weight of the filter residue to the filter residue obtained in step (1), use sodium citrate solution to adjust the pH value of the system to 5.0, add 0.8% of the filter residue weight of cellulase with an enzyme activity...

Embodiment 2

[0073] Embodiment 2, the preparation method of the Chinese medicine granule preparation that the present invention is used for the treatment of gout

[0074] (1) extract

[0075] Mix 5 kg of traditional Chinese medicine composition (7 parts of Polygonum cuspidatum, 6 parts of Plantain, 6 parts of Ligustrum lucidum, and 3 parts of honeycomb), pulverize, add 70% ethanol that is 8 times the total weight of medicinal materials, and reflux extraction twice, each time 2 hours, filter, combine the filtrates and concentrate to remove ethanol to obtain the Chinese medicine extract, and set aside, the filter residue is dried at 60°C, pulverized, and set aside;

[0076] (2) Saccharification

[0077] a. Add water three times the weight of the filter residue to the filter residue obtained in step (1), use sodium citrate solution to adjust the pH of the system to 4.5, add 0.6% of the filter residue weight of cellulase with an enzyme activity of 30,000u / g, and heat at 50°C Shake the water ...

Embodiment 3

[0091] Embodiment 3, the preparation method of the Chinese medicine granule preparation that the present invention is used for the treatment of gout

[0092] (1) extract

[0093] Mix 5 kg of traditional Chinese medicine composition (7 parts of Polygonum cuspidatum, 6 parts of Plantain, 6 parts of Ligustrum lucidum, and 3 parts of honeycomb), pulverize, add 70% ethanol 9 times the total weight of medicinal materials, and reflux extraction twice, each time 3 hours, filter, combine the filtrates and concentrate to remove ethanol to obtain the Chinese medicine extract, and set aside, the filter residue is dried at 60°C, pulverized, and set aside;

[0094] (2) Saccharification

[0095] a. Add water three times the weight of the filter residue to the filter residue obtained in step (1), use sodium citrate solution to adjust the pH of the system to 5.5, add 1.0% of the filter residue weight of cellulase with an enzyme activity of 30000u / g, and heat at 50°C Under the shaking water b...

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PUM

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Abstract

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine granular preparation for treating gout and a preparation method thereof. The preparation method of the traditional Chinese medicine granular preparation for treating gout comprises extraction, saccharification, fermentation, mixing and spray drying, and then the spherical traditional Chinese medicine granular preparation is obtained finally. According to the preparation method of the traditional Chinese medicine granular preparation, the process is stable, the yield is high, the prepared traditional Chinese medicine granular preparation has the effect on reduction of uric acid and the preparation method can be applied to preparation of health-care products or medicines for treating high uric acid.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine granule preparation for treating gout and a preparation method thereof. Background technique [0002] Uric acid is the end product of purine metabolism in the human body. The main component of uric acid is trioxypurine, and its alcohol form is weakly acidic. [0003] Under normal circumstances, there are about 1,200 mg of uric acid in the body, about 600 mg is newly generated every day, and 600 mg is excreted at the same time, which is in a balanced state. However, if the body produces too much uric acid and it is too late to excrete or the uric acid excretion mechanism degrades, the body will retain too much uric acid. When the blood uric acid concentration is greater than 7 mg / dL, the body fluids will become sour and affect the normal function of human cells. If left untreated for a long time, it will cause gout...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/704A61K36/752A61K9/16A61P19/06A61K35/64
Inventor 王一飞高旭华廖晓凤
Owner GUANGDONG ROC MEDICINAL TECH CO LTD