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Composite medical pressure-sensitive adhesive and preparation method thereof

A pressure-sensitive adhesive and medical technology, applied in the field of pressure-sensitive adhesive, can solve the problems of toxic and side effects, poor air permeability of the pressure-sensitive adhesive, whitening of the skin, etc., and achieve the effects of good mechanical properties and improved medical value.

Inactive Publication Date: 2015-09-02
SUZHOU BEC BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, pressure-sensitive adhesives also have poor air permeability, and long-term use will cause water accumulation on the skin, making the skin white and other problems.
In addition, commonly used pressure-sensitive adhesives can cause skin irritation or toxic side effects, reducing their biocompatibility

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] A composite medical pressure-sensitive adhesive, comprising the following components in parts by weight: 50 parts of ethyl α-cyanoacrylate, 10 parts of dibutyl phthalate, 10 parts of methacrylic acid, 5 parts of potassium alginate, 15 parts of Yahunu extract and 1 part of sweetgum resin; among them, the extraction method of Yahunu extract is as follows: After adding water to extract the original Yahunu medicinal material, concentrate, add ethanol until the volume concentration ratio of ethanol is 40~60 %, filter, take the supernatant, and recover ethanol until the volume concentration ratio of ethanol is lower than 2-5%.

[0020] The preparation method of composite medical pressure-sensitive adhesive is as follows:

[0021] (1) Weigh each component by weight;

[0022] (2) Mix ethyl α-cyanoacrylate, dibutyl phthalate, and methacrylic acid in an open mixer for 25 minutes, then add alginate, yahunu extract, and sweetgum resin Continue to knead for 25 minutes to make it e...

Embodiment 2

[0024] A composite medical pressure-sensitive adhesive, comprising the following components in parts by weight: 58 parts of ethyl α-cyanoacrylate, 15 parts of dibutyl phthalate, 18 parts of methacrylic acid, 8 parts of potassium alginate, 23 parts of Yahunu extract and 4 parts of sweetgum resin; among them, the extraction method of Yahunu extract is as follows: add water to extract Yahunu raw material, concentrate, add ethanol until the volume concentration ratio of ethanol is 40~60 %, filter, take the supernatant, and recover ethanol until the volume concentration ratio of ethanol is lower than 2-5%.

[0025] The preparation method of composite medical pressure-sensitive adhesive is as follows:

[0026] (1) Weigh each component by weight;

[0027] (2) Mix ethyl α-cyanoacrylate, dibutyl phthalate, and methacrylic acid in an open mixer for 28 minutes, then add alginate, Yahunu extract, and sweetgum resin Continue to knead for 26 minutes to make it evenly dispersed, and then u...

Embodiment 3

[0029] A composite medical pressure-sensitive adhesive, comprising the following components in parts by weight: 60 parts of ethyl α-cyanoacrylate, 16 parts of dibutyl phthalate, 20 parts of methacrylic acid, 10 parts of potassium alginate, 24 parts of Yahunu extract and 6 parts of sweetgum resin; among them, the extraction method of Yahunu extract is as follows: add water to extract Yahunu raw material, concentrate, add ethanol until the volume concentration ratio of ethanol is 40~60 %, filter, take the supernatant, and recover ethanol until the volume concentration ratio of ethanol is lower than 2-5%.

[0030] The preparation method of composite medical pressure-sensitive adhesive is as follows:

[0031] (1) Weigh each component by weight;

[0032] (2) Mix ethyl α-cyanoacrylate, dibutyl phthalate, and methacrylic acid in an open mixer for 32 minutes, then add alginate, Yahunu extract, and sweetgum resin Continue to knead for 28 minutes to make it evenly dispersed, and then ...

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PUM

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Abstract

The invention provides a composite medical pressure-sensitive adhesive and a preparation method thereof. The composite medical pressure-sensitive adhesive comprises the following components: alpha-cyan ethyl acrylate, dibutyl phthalate, methacrylic acid, alginate, a cissampelos pareira extract and sweetgum resin, wherein the cissampelos pareira extract is extracted by adding water into a crude cissampelos pareira material to extract, concentrating, adding ethanol until the volume concentration of ethanol is 40-60%, filtering to obtain the supernate, and by recycling the ethanol until the volume concentration of the ethanol is less than 2-5%. The preparation method comprises the following steps: mixing and smelting alpha-cyan ethyl acrylate, dibutyl phthalate and methacrylic acid in an open mill, adding alginate, the cissampelos pareira extract and the sweetgum resin, continuously smelting until the components are uniformly dispersed, and vulcanizing by using a press vulcanizer, thereby obtaining the composite medical pressure-sensitive adhesive of requested thickness. Compared with the prior art, the composite medical pressure-sensitive adhesive has the advantages of good mechanical property, good biocompatibility, good injury heal promotion effect and the like.

Description

technical field [0001] The invention relates to the field of pressure-sensitive adhesives, in particular to a composite medical pressure-sensitive adhesive and a preparation method thereof. Background technique [0002] Pressure-sensitive adhesive is a type of adhesive that can be firmly bonded to the adherend only by applying a slight pressure. Because the pressure-sensitive adhesive has a certain initial tack and stickiness, and can be used repeatedly without pollution, and has no pollution to the adhered surface after peeling off, it has been widely used in electronic insulation, electronic component processing, and color printing. , military anti-drug products, automotive interiors and medical and many other fields. Among them, medical pressure-sensitive adhesives have particularly high performance requirements, which need to meet: (1) good adhesion to various skin types (dry, wet); (2) can be removed without leaving any residue or causing Skin damage; not irritating...

Claims

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Application Information

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IPC IPC(8): C09J4/04C09J4/02C09J11/06
Inventor 李苏杨徐勤霞李文遐
Owner SUZHOU BEC BIOLOGICAL TECH
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