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New application of Embelia parviflora Wall. in preparation of medicines for treating and/or preventing cell aberration

A technology of Angelica vine and new use, applied in the field of new use of Angelica vine in the preparation of drugs for treating and/or preventing cell aberrations, and achieving the effect of high safety

Active Publication Date: 2015-09-30
GUANGXI WUZHOU PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] There is currently no literature that mentions Angelica vine, Angelica vine extract, or Angelica vine total flavonoids for the treatment and / or prevention of cellular aberrations

Method used

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  • New application of Embelia parviflora Wall. in preparation of medicines for treating and/or preventing cell aberration
  • New application of Embelia parviflora Wall. in preparation of medicines for treating and/or preventing cell aberration

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1: the preparation of angelica vine extract

[0035] Take 10kg Angelica sinensis and pulverize, add concentration and be 80% ethanol water bath and extract 3 times, the ethanol consumption of each time is respectively 12 times, 10 times, 8 times of the total weight of medicinal materials, the water bath temperature is 70 ℃, and each extraction time is respectively 60min, 50min, 40min, combine the extracts, concentrate, filter, and dry to obtain Angelica vine extract.

Embodiment 2

[0036] Embodiment 2: the preparation of the total flavonoids of Angelica vine

[0037] Take 10kg of Angelica sinensis and grind it, add 60% ethanol and microwave extraction 3 times, the amount of ethanol each time is 15 times, 10 times, 8 times of the total weight of the medicinal materials, and the extraction time is 20min, 15min, 10min respectively, combined The extract is concentrated and filtered, the filtrate is adsorbed by ADS17 resin, eluted with 80% ethanol, the eluate is concentrated, and vacuum-dried to obtain the total flavonoids of Angelica vine.

[0038] Taking rutin as the reference substance, the yield of total flavonoids in Angelica vine was 0.29%.

Embodiment 3

[0039] Embodiment 3: the preparation of the total flavonoids of Angelica vine

[0040] Take 10kg Angelica vine and pulverize it, add 80% ethanol, extract 2-3 times with 780W microwave, each ethanol dosage is 12 times of the total weight of medicinal materials, each extraction time is 15min, combine the extracts, concentrate under reduced pressure, Add diatomaceous earth to filter, and the filtrate is adsorbed by ADS17 resin, eluted with 70% ethanol, the eluate is concentrated, and vacuum-dried to obtain total flavonoids of Angelica vine.

[0041] Taking rutin as the reference substance, the yield of total flavonoids in Angelica vine was 0.43%.

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Abstract

The invention relates to a new application of Embelia parviflora Wall., namely a new application of Embelia parviflora Wall. in the preparation of medicines for treating and / or preventing cell aberration, especially a new application of an Embelia parviflora Wall. extract and general flavone of Embelia parviflora Wall. in the preparation of medicines for treating and / or preventing cell aberration.

Description

technical field [0001] The present invention relates to the new application of Angelica vine, especially the new application of Angelica vine extract and the total flavonoids of Angelica vine, that is, the new application in the preparation of medicines for treating and / or preventing cell aberration. Background technique [0002] Modern immunology research and environmental pollution surveys have shown that harmful factors such as food chain pollution, drinking water source pollution, industrial air pollution, and radioactive pollution produced by human activities enter the environment, causing changes in the structure and function of the environmental system, resulting in human beings in their daily diet. , breathing, skin contact and use of chemical drugs, they are inevitably exposed to various cell distortion environments, resulting in the distortion of living body cells, which greatly increases the probability of tumor occurrence, and reduces the reproduction of human, an...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61P43/00
Inventor 陈瑛郑志远许巍罗艳
Owner GUANGXI WUZHOU PHARMA GRP
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