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Artificial skin and preparation method thereof

A technology of artificial skin and epidermis, which is applied in the field of artificial skin and its preparation, and can solve the problems that artificial skin cannot form full-thickness skin, etc.

Inactive Publication Date: 2015-11-18
SUZHOU PANSHENG BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But Apligraf TM Artificial skin is not truly complete skin, and even after transplantation, it cannot form full-thickness skin including skin appendages such as hair, sebaceous glands, etc.

Method used

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  • Artificial skin and preparation method thereof
  • Artificial skin and preparation method thereof
  • Artificial skin and preparation method thereof

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Embodiment Construction

[0066] The invention discloses an artificial skin and a preparation method thereof. Those skilled in the art can refer to the content herein and use this method to prepare the artificial skin and realize its application. In particular, it should be pointed out that all similar replacements and modifications are obvious to those skilled in the art, and they are all considered to be included in the present invention. The artificial skin of the present invention has been described by way of preferred embodiments, and it is obvious that relevant personnel can make appropriate changes and combinations to the artificial skin, its preparation method and application without departing from the content, spirit and scope of the present invention. And apply the technology of the present invention.

[0067] All the reagents and raw materials used in the artificial skin provided by the present invention and its preparation method can be purchased from the market.

[0068] The present inve...

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Abstract

The invention belongs to the technical field of tissue engineering, and discloses artificial skin and a preparation method thereof. The artificial skin comprises epithelial cells, dermal cells and a biological bracket material. The preparation method comprises the following steps: compounding the dermal cells into the biological bracket material; inoculating the epithelial cells on the surfaces of the dermal cells; carrying out cultivation. As the artificial skin comprises a corium layer, an epidermal layer and active cells, and the epidermal layer comprises cuticle, the artificial skin is similar to normal skin, human skin with complete functions can be regenerated after the transplanting of the artificial skin, and the regenerated skin comprises skin appurtenant organs such as hair and sebaceous glands. Therefore, the artificial skin can be used for treating skin defect caused by inflammation, ulcer, burning and scalding, and also can be used for preparation of skin models used for disease researches, medicine testing and screening, cosmetic testing, or the like.

Description

technical field [0001] The invention belongs to the technical field of tissue engineering, in particular to an artificial skin and a preparation method thereof. Background technique [0002] Skin is an important tissue covering the body surface and internal organs. It is the barrier between the human body and the external environment. It not only plays the role of protection, secretion, metabolism and sensation, but also participates in immune response and maintains the stability of the internal environment of the body. Inflammation, ulcers, trauma, burns, tumor surgery and congenital deformities often cause skin trauma, which not only affects the appearance but also affects people's quality of life. The current common treatment for these wounds is autologous skin grafting. This method not only creates new wounds in the donor area, but also has limitations such as limited sources of normal skin and low survival rate of grafted skin. Deep and large-area burns often cause lar...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/60A61L27/40A61L27/38A61L27/24A61L27/36A61L27/20A61L27/18C12N5/071
Inventor 吴训伟邢志青
Owner SUZHOU PANSHENG BIOTECH CO LTD
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