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A kind of pharmaceutical composition for treating hyperosteogeny

A technology of bone hyperplasia and composition, which is applied in the direction of drug combination, antipyretics, and pharmaceutical formulations, and can solve the problems of increased surgical risk, high surgical cost, and difficult to guarantee curative effect

Active Publication Date: 2018-10-16
樟树市全顺日用品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The treatment of osteoporosis in modern medicine is still limited to surgical treatment. Due to the high cost of surgery, the curative effect is difficult to guarantee, and the patients are old, weak, and sick, which increases the risk of surgery. Whether it is acceptable or difficult to accept, the conservative treatment of western medicine mainly based on hormones, anti-inflammatory and analgesic can only relieve the pain for a while, and the pain will occur immediately after stopping the drug, which makes the patient very headache

Method used

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  • A kind of pharmaceutical composition for treating hyperosteogeny
  • A kind of pharmaceutical composition for treating hyperosteogeny
  • A kind of pharmaceutical composition for treating hyperosteogeny

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] The preparation of embodiment 1 pharmaceutical composition of the present invention

[0046] prescription:

[0047] Raw materials: Fangfeng 15g, Wulingzhi 10g, Angelica 12g, Chishao 20g, Duhuo 15g, Fangji 10g, Sangjisheng 15g, Rehmannia glutinosa 20g, Chuanxiong 12g, Zhicaowu 15g, Achyranthes bidentata 15g, Yuanhu 15g, safflower 10g , Clematis 15g, Guizhi 10g, Zhichuanwu 15g

[0048] Excipients: microcrystalline cellulose 100g starch 150g sodium carboxymethyl cellulose 50g

[0049] Preparation method: Take the prescribed amount of medicinal materials, add appropriate amount of water to soak for 30 minutes, heat and extract several times, filter, combine the extracts, concentrate under reduced pressure to an appropriate density; add excipients and mix well, dry at 60°C, pass through an 80-mesh sieve, and mix well , add 95% ethanol to make soft material, granulate with 16-mesh mesh; granulate after drying at 60°C, then add 50g of magnesium stearate, mix well, press into...

Embodiment 2

[0050] The preparation of embodiment 2 pharmaceutical compositions of the present invention

[0051] prescription:

[0052] Raw materials: Fangfeng 15g, Wulingzhi 10g, Angelica 12g, Chishao 20g, Duhuo 15g, Fangji 10g, Sangjisheng 15g, Rehmannia glutinosa 20g, Chuanxiong 12g, Zhicaowu 15g, Achyranthes bidentata 15g, Yuanhu 15g, safflower 10g , Clematis 15g, Guizhi 10g, Zhichuanwu 15g

[0053] Excipients: lactose 180g, starch 175g, stevia 50g

[0054] Preparation method: Take the prescribed amount of medicinal materials, add appropriate amount of water to soak for 30 minutes, heat and extract several times, filter, combine the extracts, concentrate under reduced pressure to an appropriate density; add excipients and mix well, dry at 60°C, pass through an 80-mesh sieve, and mix well , add 95% ethanol to make soft materials, granulate with a 16-mesh net, dry at 60°C and granulate, pack and seal, and make 1000 bags altogether.

Embodiment 3

[0055] The preparation of embodiment 3 pharmaceutical composition of the present invention

[0056] prescription:

[0057] Raw materials: Fangfeng 15g, Wulingzhi 10g, Angelica 12g, Chishao 20g, Duhuo 15g, Fangji 10g, Sangjisheng 15g, Rehmannia glutinosa 20g, Chuanxiong 12g, Zhicaowu 15g, Achyranthes bidentata 15g, Yuanhu 15g, safflower 10g , Clematis 15g, Guizhi 10g, Zhichuanwu 15g

[0058] Accessories: 120g sucrose, 100g fruit essence

[0059] Preparation method: Take the prescribed amount of medicinal materials, add appropriate amount of water to soak for 30 minutes, heat and extract several times, filter, combine the extracts, concentrate under reduced pressure to an appropriate density, let cool, add high-concentration ethanol, stand overnight, filter, and reduce pressure Recover until there is no alcohol smell, adjust the pH to 5.2-6.5, add auxiliary materials and mix well, add water to 10000ml, let stand, filter, sterilize and fill, and make 1000 bottles in total.

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Abstract

The invention provides a medicine composition for treating hyperostosis. The medicine composition comprises, by weight, 4-60 parts of radix sileris, 2-45 parts of trogopterus dung, 3-36 parts of angelica sinensis, 4-60 parts of red peony roots, 2-60 parts of radix angelicae pubescentis, 3-50 parts of radix stephaniae tetrandrae, 3-50 parts of herba taxilli, 5-60 parts of prepared radix rehmanniae, 3-48 parts of ligusticum wallichii, 2-30 parts of prepared kusnezoff monkshood roots, 3-60 parts of radix achyranthis bidentatae, 2-45 parts of rhizoma corydalis, 2-40 parts of safflowers, 4-50 parts of clematis roots, 5-60 parts of cassia twigs and 2-30 parts of prepared Sichuan aconite roots. The medicine composition has the advantages that various medicines are precise and appropriate in compatibility and complement one another, and accordingly the medicine composition can be effectively used for treating hyperostosis diseases of various positions such as lumbar vertebras, knee joints and cervical vertebras, is safe and nontoxic and is a novel option for clinical medication.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating hyperosteogeny. Background technique [0002] Osteoproliferative disease, referred to as hyperosteogeny, is one of the diseases with a high incidence rate among middle-aged and elderly people, and it is also one of the most common diseases in orthopedics. The incidence rate of hyperosteogeny in the elderly over 50 years old is 98%. Research data shows that the average person has degenerative changes from the age of 20, and at the age of 40, almost 90% of people have more or less proliferative changes in the weight-bearing joints, but most of them are very light and will not affect their health. As the age increases, the incidence of hyperosteogeny is higher, and it is more common in middle-aged and elderly people. With the changes in the lifestyle of modern society and the acceleration of the pace of life, the number of people who work with their heads down and sit in the office for a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/804A61P19/08A61P29/00A61K35/24
Inventor 熊永爱苏柘僮张帅杰
Owner 樟树市全顺日用品有限公司