Homogeneous olaquindox granules and preparation method thereof

Abstract

The invention provides homogeneous olaquindox granules and a preparation method thereof. The homogeneous olaquindox granules are prepared form, by weight, 2-60% of olaquindox raw materials and 40-98% of auxiliary materials; one or several of hydrogenated castor oil, hydrogenated soybean oil, stearic acid, glyceryl monostearate, solid lipid, animal wax, vegetable wax and solid-state polyethylene glycol is / are selected as the auxiliary materials. The preparation method comprises the steps that firstly, at 60-90 DEG C, the auxiliary materials are heated to be melted and stirred evenly, and then the olaquindox raw materials and the melted auxiliaries are mixed, sheared and evenly stirred to obtain mixed liquor; secondly, the mixed liquor is sprayed and condensed to be prepared into the granules, and then the homogeneous olaquindox granules are obtained. According to the homogeneous olaquindox granules and the preparation method thereof, main medicine in the homogeneous olaquindox granules is even in distribution and smooth in surface, and the fluidity and dispersity of the granules are improved; when the granules are used, the granules are easy to mix, and the problems that medicine is left and animals are poisoned due to the fact that olaquindox preparations are poor in homogeneity, the olaquindox preparations are stuck on the wall, and the olaquindox preparations are mixed unevenly when the olaquindox preparations are used.

Description

technical field [0001] The invention belongs to the technical field of preparation of veterinary drugs, and in particular relates to homogeneous olaquindox granules and a preparation method thereof. Background technique [0002] With the high intensification of animal husbandry, a large number of antibacterial drugs are used to prevent and control diseases, resulting in the residue of antibacterial drugs in animal food, which poses a serious threat to people's health. Pollution during feed processing or transportation (such as feed crushing, mixing equipment not cleaned and contaminated) is also a major factor causing animal food drug residues. At the same time, uneven drug content or uneven drug mixing leads to overdose or even poisoning of some animals from time to time. Therefore, when farms use antibiotic products, they always spend a lot of time mixing and cleaning mixers, troughs, etc., especially when using powdered antibiotic preparations. [0003] Olaquindox has t...

AI Technical Summary

Problems solved by technology

[0006] In order to solve the problems of wall sticking, polluted feed and uniformity of the existing olaquindox preparations, the present invention proposes a kind of homogeneous granule of olaquindox, which is screened by auxiliary materials and matched with the raw material of olaquindox, so that the main drug is evenly distributed, The surface is smooth and easy to mix, which improves the fluidity and dispersibility of the granules, and solves the problems of olaquindox sticking to the wall and uneven mixing, causing drug residues and animal poisoning

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