Method for preparing radix astragali extracting solution

An astragalus extract and the technology of the extract, which are applied in the field of preparation of astragalus extract, can solve problems such as poor stability and less active ingredient retention, and achieve the effect of saving costs

Active Publication Date: 2015-12-30
SHANGHAI FOREST CABIN BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The present invention aims at the disadvantages of less active ingredient retention, poor stability, and the use of unsafe solvents such as ethanol in the preparation of traditional Astragalus extract, and provides a preparation method of Astragalus extract, which specifically adopts extraction-micr

Method used

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  • Method for preparing radix astragali extracting solution

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Experimental program
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Embodiment 1

[0036] The present embodiment provides a preparation method of astragalus extract, the preparation method comprising the following steps:

[0037] Extraction: Astragalus decoction pieces are boiled for 2 hours with 6 times of water, and the dregs are boiled for 1 hour with 4 times of water, and the extracts are combined;

[0038] Microfiltration: the extract is filtered with a 1μm ceramic membrane, and the filtrate is filtered with a 0.2μm ceramic membrane at a pressure of 10bar;

[0039] Ultrafiltration: The filtrate is ultrafiltered with a membrane with a molecular weight cut-off of 10000D, the operating pressure is 3bar, and when the ultrafiltration is about 30% of the reflux liquid, add the same amount of water and continue the ultrafiltration until the amount of the exudate is equal to the initial extraction liquid;

[0040] Membrane concentration: ultrafiltration exudate is concentrated with a membrane with a molecular weight cut-off of 100-200D, the operating pressure i...

Embodiment 2

[0045] The present embodiment provides a preparation method of astragalus extract, the preparation method comprising the following steps:

[0046] Extraction: Astragalus decoction pieces were boiled for 3 hours with 5 times of water, the dregs were boiled for 1 hour with 6 times of water, and the extracts were combined;

[0047] Microfiltration: the extract is filtered with a 0.45μm ceramic membrane, and the filtrate is filtered with a 0.1μm ceramic membrane at a pressure of 15bar;

[0048] Ultrafiltration: The filtrate is ultrafiltered with a membrane with a molecular weight cut-off of 8000D, the operating pressure is 6bar, and when the ultrafiltration reaches about 20% of the reflux liquid, add the same amount of water and continue the ultrafiltration until the amount of the exudate is equal to the initial extraction liquid;

[0049] Membrane concentration: ultrafiltration exudate is concentrated with a membrane with a molecular weight cut-off of 100-200D, the operating pres...

Embodiment 3

[0054] The present embodiment provides a preparation method of astragalus extract, the preparation method comprising the following steps:

[0055] Extraction: Astragalus decoction pieces are boiled for 2 hours with 8 times of water, and the dregs are boiled for 2 hours with 3 times of water, and the extracts are combined;

[0056] Microfiltration: the extract is filtered with a 1μm ceramic membrane, and the filtrate is filtered with a 0.2μm ceramic membrane at a pressure of 12bar;

[0057] Ultrafiltration: The filtrate is ultrafiltered with a membrane with a molecular weight cut-off of 10000D, the operating pressure is 4bar, and when the ultrafiltration is about 30% of the reflux liquid, add the same amount of water and continue the ultrafiltration until the amount of the exudate is equal to the initial extraction liquid;

[0058] Membrane concentration: ultrafiltration exudate is concentrated with a membrane with a molecular weight cut-off of 150D, the operating pressure is 1...

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Abstract

The invention discloses a method for preparing a radix astragali extracting solution. The preparing method includes the following steps of extracting, microfiltration, ultrafiltration, membrane concentration, hydrolysis, redissolving and nanofiltration, so that the radix astragali extracting solution is obtained. Compared with the prior art, the yield of astragaloside is increased, reservation of radix astragali micromolecule ingredients such as oligosaccharide and flavonoid is increased, the stability of the radix astragali extracting solution is enhanced, the color of the radix astragali extracting solution and color change in the long-term placing process are reduced, salt in the extracting solution is removed, and the phenomena of viscosity reduction, breaking of emulsion and the like caused when the extracting solution is added into a cosmetic formula are avoided. No ethyl alcohol and resin are used, so that environmental protection and safety are achieved, and cost is reduced.

Description

technical field [0001] The invention relates to a preparation method of astragalus extract. Background technique [0002] The extracts used in cosmetics are rarely mentioned in articles or patents, so we can only refer to the process of important injections, which are also liquid preparations, which are relatively close to the extracts of cosmetics. [0003] Traditional astragali injection technology, such as patents CN201210422499.6, CN200710099116.5, CN201210112210.0, CN99106225.6, CN0311478.5 and other disclosed technical solutions, generally carry out 2 to 3 times of alcohol precipitation after extraction, and then carry out acid-base adjustment , water precipitation, activated carbon decolorization, or resin-passing refining steps, the disadvantage of which is that the loss of active ingredients such as astragaloside IV and calycosin is relatively large. In addition, a large amount of ethanol, resin, etc. are used, which is not environmentally friendly and safe. [000...

Claims

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Application Information

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IPC IPC(8): A61K36/481A61K8/97
Inventor 陈贤高宏旗
Owner SHANGHAI FOREST CABIN BIOLOGICAL TECH
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