Biodegradable material

Abstract

To provide a biodegradable material that has sufficient mechanical strength, considering in vivo use also, and that can suppress pH changes caused by an acidic degradation product. Provided is a biodegradable material the base material of which is polyester, and that is characterized by comprising calcium phosphate particles having an average particle diameter of 10 to 1,000 nm.

Description

technical field [0001] The invention relates to a biodegradable material. Background technique [0002] Biomaterials using biodegradable polymers as base materials are being studied as ideal members for use in living bodies, such as scaffolds and bone fixation members. [0003] For example, Patent Document 1 describes a stent for blood vessels made of polylactic acid (PLLA) with the optical purity of the L-form in a predetermined range and the weight average molecular weight in a predetermined range. After being implanted in the living body, it is decomposed and disappears in the living body. [0004] However, when such a biodegradable polyester is applied to a living body, an acidic decomposition product is produced when the polyester is decomposed in the body, which may cause inflammation, which is regarded as a problem. [0005] In response to this problem, in Patent Document 2, a scaffold is described, which not only contains polylactic acid as a biodegradable polymer,...

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Problems solved by technology

[0010] However, the stent described in Patent Document 2 may not necessarily have sufficient mechanical strength, and may not sufficiently neutralize the acidic components of polyester decomposition products, so that inflammation in the living body may not be sufficiently suppressed.

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