Biological value detection method for evaluating anticoagulant activity of panax notoginseng

A technology of biological potency and notoginseng, which is applied in the preparation of test samples, material inspection products, and testing of pharmaceutical preparations, can solve problems such as difficult quality control, complex ingredients, and insufficient quality of medicinal materials or preparations. Tight, easy-to-use effects

Inactive Publication Date: 2016-01-27
302 MILITARY HOSPITAL OF CHINA
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  • Abstract
  • Description
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Problems solved by technology

Traditional Chinese medicine is affected by many factors such as variety, origin, processing method, etc., resulting in the phenomenon that the material basis of Chinese medicine quality changes greatly and the quality is difficult to control. Moreover, its compos

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  • Biological value detection method for evaluating anticoagulant activity of panax notoginseng
  • Biological value detection method for evaluating anticoagulant activity of panax notoginseng
  • Biological value detection method for evaluating anticoagulant activity of panax notoginseng

Examples

Experimental program
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Example Embodiment

[0059] Example 1

[0060] Test product: Panax notoginseng sample (place of origin: Xiaoshao Street Office, Guandu District, Kunming City, Yunnan Province)

[0061] Reference substance: Aspirin (manufacturer: Shanghai Fusheng Industrial Co., Ltd.; batch number: 20130523), assigned a value of 1 mg = 0.5u, and u is the number of units of anticoagulant activity potency of Panax notoginseng

[0062] Normal saline: produced by Shijiazhuang No.4 Medicine Co., Ltd.; batch number: 121007405

[0063] Automatic coagulation analyzer: SysmexCA-0007, Japan

[0064] a. Compare the effects of different extraction methods on the anticoagulant activity of Panax notoginseng samples

[0065] Reflux extraction: take 20g of Panax notoginseng coarse powder, put it in a ground round bottom flask, add deionized water, the volume of the deionized water in milliliters is 10 times the weight of the notoginseng coarse powder in grams, soak for 30min , reflux for extraction for 1 h, the extract was subj...

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Abstract

The application provides a biological value detection method for evaluating anticoagulant activity of panax notoginseng. The biological value detection method is simple and convenient. Quality of the panax notoginseng can be evaluated as a whole by using the detection method, and the quality of the panax notoginseng of different habitats, different batches, and different growing time can be evaluated.

Description

technical field [0001] The application relates to a biopotency assay method for evaluating the anticoagulant activity of Panax notoginseng. Background technique [0002] Sanqi is a commonly used traditional Chinese medicine, and its legal source is the dried root and rhizome of Panax notoginseng (Burk.) F.H.Chen, a plant of Araliaceae. Also known as Tianqi, Shanqi, Jinbuhuan, etc. Branch roots are traditionally called "tendons", and rhizomes are traditionally called "shears" [5]. Panax notoginseng was first recorded in "Compendium of Materia Medica", and has a history of more than 400 years of medication. It has a long-standing reputation at home and abroad, and has the reputation of "hemostatic medicine" [12-14]. Its nature is sweet, slightly bitter, warm; it belongs to the Liver and Stomach Meridians. It has the effects of dissipating blood stasis and stopping bleeding, reducing swelling and relieving pain. Clinically, it is mostly used for promoting blood circulation...

Claims

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Application Information

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IPC IPC(8): G01N33/15G01N1/28
Inventor 王伽伯肖小河王艳辉张雅铭
Owner 302 MILITARY HOSPITAL OF CHINA
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