Medicine for treating lung cancer radiotherapy complication

A tumor radiotherapy and complication technology, applied in the field of traditional Chinese medicine, can solve the problems of inability to effectively control the development of lung injury, large adverse reactions, immunosuppression, etc., and achieve the effect of improving the quality of life, significant curative effect, and small side effects.

Inactive Publication Date: 2016-02-24
苏赵珍
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there is still no safe and effective treatment for complications of radiotherapy for lung tumors at home and abroad. Adrenocorticosteroids combined with antibiotics are often used in clinical practice, supplemented by oxygen inhalation, asthma relief, and cough relief. Superinfection, flora imbalance, immunosuppression, etc., and despite the use of glucocorticoids, a considerable number of patients cannot effectively control the development of lung injury, and eventually progress to pulmonary fibrosis

Method used

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preparation example Construction

[0053] The present invention also provides a preparation method of the above-mentioned Chinese medicine composition, when the Chinese medicine composition is prepared into an oral liquid, specifically:

[0054]In the first step, the components are mixed in proportion, placed in an ultrafine pulverizer and pulverized for 20 to 40 minutes, and the pulverized mixture is dissolved in ethanol with an alcohol concentration of 80% to 90%, and extracted twice by reflux ~4 times, filter, combine the filtrates, concentrate under reduced pressure to remove ethanol, and obtain a dry paste, wherein the amount of ethanol added is 2 to 4 times the quality of the mixture in the first step, followed by drying and pulverizing with a superfine pulverizer for 20 Minutes to 40 minutes, dissolve the pulverized powder in water 3 to 5 times its mass, filter, add hydrochloric acid with a concentration of 10% to adjust the pH to 3 to 4, stand still for 2 to 4 hours, filter, and the filtrate Extract wit...

Embodiment 1

[0061] The preparation of embodiment 1 oral liquid 1

[0062] Rehmannia glutinosa 25g, Radix Asparagus 35g, Paeoniae Alba 30g, Campanulaceae 20g, Cordyceps sinensis 35g, Fritillaria sichuanensis 25g, sarcocarpus 20g, Eclipta chinensis 25g, Cornus officinalis 35g, loquat leaves 20g, Shouwu vine 30g, Scrophularia scrophulariae 25g, Mix 35g of honeysuckle, 30g of Scutellaria baicalensis, 20g of licorice, 35g of sealwort, 45g of American ginseng, 25g of three-lens grass, 30g of native ginseng, 25g of Pinellia chinensis, 15g of wintersweet and 15g of peacock tail. After the mixture was dissolved in 1.8kg of ethanol with an alcohol concentration of 90%, reflux extracted 3 times, filtered, combined filtrates, concentrated under reduced pressure to remove ethanol, obtained a dry paste, dried subsequently, and pulverized for 30 minutes with an ultrafine pulverizer , the pulverized powder is dissolved in water 3 times its mass, filtered, added with 10% hydrochloric acid to adjust the pH...

Embodiment 2

[0063] The preparation of embodiment 2 oral liquid 2

[0064] Rehmannia glutinosa 23g, Radix Asparagus 33g, Paeoniae Alba 28g, Campanulaceae 18g, Cordyceps sinensis 33g, Fritillaria sichuanensis 23g, sarcocarpus 18g, Eclipta chinensis 23g, Cornus officinalis 33g, loquat leaves 18g, Shouwu vine 28g, Scrophularia scrophulariae 23g, Honeysuckle 33g, Scutellaria baicalensis 28g, licorice 18g, Polygonatum 33g, American ginseng 43g, Sansengcao 23g, native ginseng 28g, pinellia 23g, wintersweet 13g and peacock tail 13g are mixed, placed in an ultrafine pulverizer for 30 minutes, and the pulverized The final mixture was dissolved in 1.5 kg of ethanol with an alcohol concentration of 90%, extracted 3 times by reflux, filtered, combined filtrates, concentrated under reduced pressure to remove ethanol, and obtained a dry paste, which was subsequently dried and pulverized for 30 minutes with an ultrafine pulverizer , the pulverized powder is dissolved in water 3 times its mass, filtered, ...

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Abstract

The invention provides a traditional Chinese medicine composition for treating lung cancer radiotherapy complication. The traditional Chinese medicine composition is prepared from prepared rehmannia roots, asparagus cochinchinensis, radix paeoniae alba, platycodon grandiflorum, cordyceps sinensis, bulbus fritillariae cirrhosae, glabrous sarcandra herbs, eclipta, dogwood, folium eriobotryae, vines of multiflower knotweed, radix scrophulariae, honeysuckle, scutellaria baicalensis, liquorice, rhizoma polygonati, American ginseng, rice galingale herbs, talinum crassifolium, pinellia ternate, chimonanthus nitens and peacock tail. The traditional Chinese medicine composition has definite functions of resisting to lung cancer radiotherapy complication, whole-body centralization is considered, and immunity is enhanced, so that recurrence and metastasis of tumor are reduced and delayed, more superiority is achieved compared with traditional hormonotherapy, after the traditional Chinese medicine is adopted to treat lung cancer radiotherapy complication, the traditional Chinese medicine composition has great advantages, the curative effect is remarkable, the side effect is little, the life quality of a patient can be improved, and the traditional Chinese medicine composition is worthy of clinic application and popularization.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a medicine for treating complications of lung tumor radiotherapy. Background technique [0002] Worldwide, the incidence and mortality of lung cancer are increasing year by year. According to statistics, there are 1.2 million new cases every year in the world, accounting for 12.1% of the total incidence of cancer. Among cancer deaths, lung cancer accounts for 16.9%, with 918,000 deaths per year. Epidemiologists predict that lung cancer has become one of the most common diseases in the 21st century. The mortality rate of lung cancer is very high, and it seriously threatens people's health and life. Because 70% of the patients are already in the middle and late stages when they are diagnosed with the disease, the best time for surgery has been missed. Therefore, comprehensive treatment based on radiotherapy should be adopted. However, the lung is a radiosensi...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61P35/00
CPCA61K36/804A61K9/0053A61K9/0073A61K9/08A61K36/068A61K36/11A61K36/185A61K36/258A61K36/28A61K36/346A61K36/355A61K36/40A61K36/484A61K36/539A61K36/65A61K36/704A61K36/71A61K36/73A61K36/808A61K36/8888A61K36/8905A61K36/8965A61K36/8966A61K36/8969A61K47/12A61K47/26
Inventor 不公告发明人
Owner 苏赵珍
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