Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Optimal control system and method for three-dimensional bio-printing aquogel supports

A technology of three-dimensional biological and optimal control, which is applied in the field of biomedical engineering and can solve problems such as insufficient precision control

Active Publication Date: 2016-04-13
HANGZHOU DIANZI UNIV
View PDF2 Cites 21 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] One purpose of the present invention is to address the deficiencies of the prior art, to overcome the defects of insufficient structural precision control of the existing 3D bioprinted hydrogel scaffolds, and propose an optimal control system for a 3D bioprinted hydrogel scaffold based on OCT technology

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Optimal control system and method for three-dimensional bio-printing aquogel supports
  • Optimal control system and method for three-dimensional bio-printing aquogel supports
  • Optimal control system and method for three-dimensional bio-printing aquogel supports

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0067] The present invention will be further explained below in conjunction with the drawings:

[0068] The present invention provides a precise control flow chart of the OCT-based three-dimensional bioprinting hydrogel scaffold, such as figure 1 As shown, the geometric structure of the stent to be printed is designed based on computer-aided design technology, and the hydrogel stent is manufactured using three-dimensional bioprinting equipment. The OCT system is used to quantitatively characterize the morphological parameters of the actual hydrogel stent; the deviation between design and manufacturing is compared and analyzed The correlation between the deviation and the design value, summarize the experience function; according to the experience function feedback to guide the design and printing of the hydrogel scaffold, repeat the above steps until the hydrogel scaffold consistent with the design is printed. figure 2 The block diagram of the optimized control system of the 3D b...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
pore sizeaaaaaaaaaa
Login to View More

Abstract

The invention discloses an optimal control system and method for three-dimensional bio-printing aquogel supports. The system comprises a quantitative visualization device for the three-dimensional bio-printing aquogel supports based on optical coherence tomography scanning and three-dimensional bio-printing equipment; the visualization device comprises a light source, a low-coherence interference module, a sample scanning module, an interference signal detecting module and a computer. According to the method, the quantitative structure characteristics of the three-dimensional bio-printing aquogel supports are obtained through the OCT technology, the designing and the printing of the supports are fed back on the basis of the results of the quantitative structure characteristics, and the stability and the controllability of three-dimensional manufacturing of the supports are improved by lowering the difference between the designing and the printing through iteration. According to the invention, the requirements of optimal control of three-dimensional bio-printing aquogel for high resolution and wide-range and three-dimensional fast scanning can be met, non-destructive and non-intrusive fast imaging of the whole supports can be realized through the OCT technology, and the information of the whole supports and local shape features of space is quantitatively analyzed based on the algorithm automatically selecting object regions.

Description

Technical field [0001] The invention belongs to the technical field of biomedical engineering, and relates to an optimized control system and method for a three-dimensional printing hydrogel support. Background technique [0002] As an important part of tissue engineering, scaffolds provide necessary space and environment for cell growth. Its chemical composition and physical structure can affect cell activities, such as cell adhesion, migration, proliferation and differentiation. Hydrogels have good biocompatibility, degradability, hydrophilicity and powerful ability to encapsulate cells, which makes hydrogels widely used in the construction of tissue engineering scaffolds. On the other hand, in some special applications, such as the manufacturing of functional tissues and organs, very strict restrictions are imposed on the porous morphology of the stent. The internal structure of the stent needs to be specially tailored to obtain the desired geometric, mechanical, and liquid tr...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): B29C67/00B33Y50/00
Inventor 王玲徐铭恩
Owner HANGZHOU DIANZI UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com