Salvia miltiorrhiza, liguspyragine hydrochloride and glucose injection for treating acute myocardial infarction

A technology for glucose injection and acute myocardial infarction, which is applied in the field of drug preparation and can solve the problems of disabled and adverse reactions of patients

Inactive Publication Date: 2016-04-20
GUIZHOU JINGFENG INJECTION +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention is to provide a treatment for myocardial infarction in view of the existing deficiencies in the existing treatment methods for myocardial infarction that can induce some serious adverse reactions, including secondary re-infarction, heart failure, etc., which can make patients disabled or dead. Shenxiong Glucose Injection for Myocardial Infarction with Good Curative Effect and Few Adverse Reactions

Method used

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  • Salvia miltiorrhiza, liguspyragine hydrochloride and glucose injection for treating acute myocardial infarction
  • Salvia miltiorrhiza, liguspyragine hydrochloride and glucose injection for treating acute myocardial infarction
  • Salvia miltiorrhiza, liguspyragine hydrochloride and glucose injection for treating acute myocardial infarction

Examples

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Embodiment 1

[0023] A Shenxiong glucose injection for treating acute myocardial infarction, wherein per kg of 5% glucose injection contains 16-18 mg of danshensu and 89-90 mg of ligustrazine.

Embodiment 2

[0025] Shenxiong glucose injection for treating acute myocardial infarction, wherein per kg of 5% glucose injection contains 3.0-4.5 mg of danshensu and 17-18 mg of ligustrazine.

Embodiment 3

[0027] Shenxiong glucose injection for treating acute myocardial infarction, wherein per kg of 5% glucose injection contains 0.65-0.8 mg of danshensu and 3.0-4.5 mg of ligustrazine.

[0028] The preparation method of the above-mentioned embodiment is the same as the preparation method of the existing glucose injection.

[0029] Above-mentioned embodiment is Shenxiong Glucose Injection and Xueshuantong Injection to the influence test of treatment adrenaline-induced myocardial infarction, specifically as follows:

[0030] 1. Experimental materials and animals

[0031] 1.1 Drugs: Shenxiong glucose injection, commercially available Xueshuantong injection (Panax Notoginseng Saponins, PNS), isoproterenol hydrochloride.

[0032] 1.2 Reagents: Creatine Kinase (Creatine Kinase, CK) kit (batch number 20141217, built in Nanjing); lactate dehydrogenase (Lactate Dehydrogenase, LDH) kit (batch number 20141220, built in Nanjing); cardiac troponin (cTn-I ) kit (lot number A21019886, Wuhan C...

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Abstract

The invention discloses a salvia miltiorrhiza, liguspyragine hydrochloride and glucose injection for treating acute myocardial infarction. Each kilogram of 5% glucose injection contains 0.65-18 mg of tanshinol and 3.0-90 mg of ligustrazine. The salvia miltiorrhiza, liguspyragine hydrochloride and glucose injection for treating acute myocardial infarction has a remarkable treatment function on acute myocardial infarction.

Description

technical field [0001] The invention relates to the technical field of medicine preparation, in particular to a Shenxiong glucose injection for treating acute myocardial infarction. Background technique [0002] Epidemiological studies have shown that with the continuous improvement of people's living standards and changes in eating habits, the incidence and mortality of cardiovascular diseases in my country and the world continue to increase, and the age of onset is gradually becoming younger. According to predictions, By 2020, global cardiovascular disease deaths may account for 36% of the total number of deaths, ranking first among various causes of death in humans [1]. So far, a lot of research has been done on the prevention and treatment of cardiovascular diseases at home and abroad. Although we have a deeper understanding of the pathological mechanisms and risk factors of many diseases, and have made a lot of progress in diagnosis, the reversal of cardiovascular diseas...

Claims

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Application Information

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IPC IPC(8): A61K31/4965A61K9/08A61P9/10A61K31/192
CPCA61K9/0019A61K9/08A61K31/192A61K31/4965A61K2300/00
Inventor叶湘武罗斌赵曲简芳马贤鹏
OwnerGUIZHOU JINGFENG INJECTION