A high-throughput magnetic extraction and enrichment device and enrichment method

An extraction, enrichment, and high-throughput technology, applied in the preparation of test samples, etc., can solve the problems of time-consuming, cumbersome processing steps, etc.

Inactive Publication Date: 2018-10-23
NANJING MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The object of the present invention is to provide a high-throughput magnetic extraction and enrichment device to solve the problems of cumbersome and time-consuming processing steps in the existing magnetic material extraction and enrichment method, which can be applied to the rapid and efficient extraction of large batches and large volumes of samples. Capture magnetic materials, and facilitate the transfer and separation of magnetic materials, improving the throughput and efficiency of sample processing

Method used

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  • A high-throughput magnetic extraction and enrichment device and enrichment method
  • A high-throughput magnetic extraction and enrichment device and enrichment method
  • A high-throughput magnetic extraction and enrichment device and enrichment method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] Such as figure 1 As shown, a high-throughput magnetic extraction and enrichment device includes an enrichment probe 23, an enrichment probe bracket 26, a support rod 5, a container tray 2, and a base 1 using electromagnetically regulated magnetism; wherein several enrichment probes 23 are fixed on Enrichment probe bracket 26, enrichment probe bracket 26 is movably connected with support rod 5, the enrichment probe bracket can move up and down along the support rod 5 through the adjustment device 27 arranged on the support rod, and support rod 5 is fixedly connected with base 1, The container tray 2 is located below the enrichment probe 23, and a container placement position 12 corresponding to the enrichment probe is set on the container tray 2. The container placement position is a container placement slot or a container placement hole, and the container placement position can be placed to contain samples to be tested container or eluent container 21; the container tra...

Embodiment 2

[0067] Such as figure 2As shown, a high-throughput magnetic extraction and enrichment device has two support rods, which are arranged on both sides of the base, which is more conducive to the stability of the equipment. In addition, a program control device 19 is provided. The program control device comprehensively controls each adjustment device. To adjust the amplitude, speed, duration, sequence, interval time, etc. of various movements, so as to realize the automation function. All the other are with embodiment 1.

Embodiment 3

[0069] Such as image 3 As shown, a high-throughput magnetic extraction and enrichment device includes an enrichment probe that uses permanent magnets to mechanically adjust the magnetism, an enrichment probe holder, a support rod, a container tray, and a base, and the enrichment probe that uses permanent magnets to mechanically adjust the magnetism It includes an inner rod 9, a permanent magnet 11 connected to the lower end of the inner rod, and an outer casing 10. The lower end of the upper opening of the outer casing is a blind end, and the permanent magnet can move up and down in the outer casing with the inner rod; the enrichment probe bracket is divided into two layers. The bracket 4 is connected to the upper part of the inner rod, the lower bracket 3 is connected to the upper part of the outer casing, the upper and lower brackets are respectively connected to the support rod 5, and the adjustment knob 8 for moving the upper bracket up and down and the lower bracket for m...

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Abstract

The invention belongs to the field of a magnetic extraction device and discloses a high-throughput magnetic extraction enrichment device and an enrichment method. The device comprises magnetic adjustable enrichment probes, an enrichment probe support, a support bar, a container tray and a pedestal, and is characterized in that several enrichment probes are fixed on the enrichment probe support, which is connected to the support bar; the support bar is connected to the pedestal; the container tray is positioned below the enrichment probes; container placement sites which are corresponding to the enrichment probes are arranged on the container tray; the container tray is connected to the support bar and the pedestal, or the container tray is placed on the pedestal or a tray support, which is connected to the support bar or the pedestal; and one or more adjusting devices which enable the enrichment probes and the container tray to carry out relative motion are arranged on the enrichment probe support, the tray support, the container tray, the support bar and / or the pedestal. The device has a simple structure, is low-cost, is flexible to move, is simple to operate, and can remarkably enhance sample treatment efficiency. The method is simple and efficient.

Description

technical field [0001] The invention belongs to the field of magnetic extraction devices, and relates to a high-throughput magnetic extraction and enrichment device and an enrichment method. A high-throughput magnetic extraction and enrichment device for magnetic extraction particles in solution. Background technique [0002] Magnetic Dispersive Solid-Phase Extraction (Magnetic Dispersive Solid-Phase Extraction, MDSPE) technology is a unique and environmentally friendly sample pretreatment technology that has emerged in recent years. Solid phase extraction technique. Different from the traditional solid phase extraction (SPE) technology, this kind of nanoparticles can be fully exposed to the system to be tested and fully contacted with it, and can absorb and extract the substance to be tested from a large volume of the system to be tested in a short time. The technology can achieve phase separation only by applying an external magnetic field, which is simple, time-saving a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N1/40
CPCG01N1/40
Inventor 赵鸿雁王中贺黄漫衍高蓉
Owner NANJING MEDICAL UNIV
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