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Medicine composition for treating headache caused after spinal anesthesia

A technique of spinal anesthesia and composition, which is applied in the field of medicine and can solve problems such as high technical requirements, inconvenient operation, and trauma

Inactive Publication Date: 2016-05-04
唐国萍
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is also the method of instilling 500ml of normal saline into the epidural space, which can significantly relieve the headache. Although the above two methods are effective, they are both traumatic, especially because patients are afraid of spinal canal puncture, and most of them are unwilling to accept it. , which requires high technical requirements, strict aseptic operation, and postoperative positions, which brings a lot of inconvenience to the operation

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Embodiment 1 capsule

[0043] Each Chinese medicinal material of the present invention was weighed in the following parts by weight: ginseng 24, schisandra chinensis 24, rehmannia glutinosa 8, Polygonatum 8, Nansha ginseng 32, Rhizoma Chuanxiong 32, Angelica sinensis 8, Digupi 4, Angelica dahurica 24.

[0044] The preparation process is as follows:

[0045] The above-mentioned Chinese medicinal materials are weighed according to the weight ratio of each of the aforementioned Chinese medicinal materials, crushed through an 80-mesh sieve, mixed uniformly, sterilized, and filled into capsules to obtain the product.

Embodiment 2

[0046] Example 2 tablet

[0047] Each Chinese medicinal material of the present invention was weighed in the following parts by weight: ginseng 24, schisandra chinensis 24, rehmannia glutinosa 8, Polygonatum 8, Nansha ginseng 32, Rhizoma Chuanxiong 32, Angelica sinensis 8, Digupi 4, Angelica dahurica 24.

[0048] The preparation process is as follows:

[0049] Weigh the above Chinese medicinal materials according to the weight ratio of the aforementioned Chinese medicinal materials, crush them, decoct twice, add 8 times the amount of water for the first decoction, soak for 2 hours, decoct for 1 hour, and filter; add 6 times of water for the second decoction Measure, decoct for 1 hour, filter; combine the filtrates; concentrate the filtrate into a thick paste, dry under reduced pressure, crush into fine powder, make granules with 75% ethanol, dry, add an appropriate amount of magnesium stearate, mix well, and press into tablets , film-coated, that is.

Embodiment 3

[0050] Embodiment 3 granules

[0051] Each Chinese medicinal material of the present invention was weighed in the following parts by weight: ginseng 24, schisandra chinensis 24, rehmannia glutinosa 8, Polygonatum 8, Nansha ginseng 32, Rhizoma Chuanxiong 32, Angelica sinensis 8, Digupi 4, Angelica dahurica 24.

[0052] The preparation process is as follows:

[0053] Weigh the above Chinese medicinal materials according to the weight ratio of the aforementioned Chinese medicinal materials, crush them, decoct twice, add 10 times of water for the first decoction, soak for 2 hours, decoct for 2 hours, and filter; add 8 times of water for the second decoction Decoct for 1 hour, filter; combine the filtrates; when the filtrate is concentrated to a clear paste with a relative density of 1.10-1.15 at 65°C, add an appropriate amount of dextrin and soft materials made of sucrose, make wet granules, pass through a 20-mesh sieve, dry, and process Granules, sieved again, bagged, that is. ...

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Abstract

The invention belongs to the technical field of medicine and relates to a medicine composition for treating a headache caused after spinal anesthesia. The medicine composition is prepared from ginseng, Chinese magnoliavine fruits, prepared rehmannia roots, rhizoma polygonatum, roots of straight ladybell, rhizoma chuanxiong, radix angelica sinensis, cortex lycii radicis and radix angelicae dahuricae. All the medicine materials are jointly used and achieve the effects of nourishing yin to promote the secretion of saliva or body fluid, invigorating qi and blood, and dispelling wind and removing obstruction in the meridians, the cerebrospinal fluid and brain pressure are restored to normal, and the purpose of treating a headache is achieved.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition for treating headache after spinal anesthesia and a preparation method thereof. Background technique [0002] Headache after spinal anesthesia is one of the common complications of subarachnoid anesthesia, which is often caused by continuous leakage of cerebrospinal fluid from the needle hole left by the puncture needle in the dura mater. Headache after spinal anesthesia. Symptoms usually appear on the second day after surgery. Most patients can relieve symptoms within a few days after infusion and symptomatic treatment. Relevant literature reports that for intractable or ineffective headaches, autologous blood can be used aseptically to inject epidural space into the epidural space at the original lumbar puncture site, and it can be used repeatedly for recurrent cases. There is also the method of instilling 500ml of normal saline into t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P29/00A61P25/00
CPCA61K36/8969A61K9/0095A61K9/1652A61K9/2009A61K9/28A61K36/23A61K36/232A61K36/236A61K36/258A61K36/34A61K36/342A61K36/57A61K36/79A61K36/804A61K36/815A61K47/26A61K2300/00
Inventor 唐国萍
Owner 唐国萍
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