Hyaluronic acid-polypeptide bonded conjugate mask and preparation method thereof

A hyaluronic acid and bonded technology, which is applied in the field of skin care products, can solve the problems of cosmetic effect, poor anti-aging effect, poor water solubility and permeability, and high content of mineral components, so as to achieve obvious cosmetic effect and increase skin elasticity. Elasticity, the effect of dilating capillaries

Active Publication Date: 2016-06-01
成都海卓派特科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

For example, the macromolecular natural collagen added in the facial mask is difficult to be absorbed by the skin, and is not suitable for human skin absorption, and its water solubility and permeability are also poor; some ingredients in the facial mask are unstable, and the cosmetic effect and anti-aging effect are not good. Short; the cleaning effect of the mask is poor, the skin care

Method used

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  • Hyaluronic acid-polypeptide bonded conjugate mask and preparation method thereof
  • Hyaluronic acid-polypeptide bonded conjugate mask and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] A hyaluronic acid polypeptide bond mask, calculated by mass percentage, contains the following components:

[0035] 0.1 part of hyaluronic acid and superoxide dismutase bond, 10.0 parts of vitamin C agent, 2.0 parts of emulsifier, 0.5 part of lanolin, 1.0 part of niacin, 5.0 parts of sage oil, 10.0 parts of glycerin, and the balance is water.

Embodiment 2

[0037] A hyaluronic acid polypeptide bond mask, calculated by mass percentage, contains the following components:

[0038] 20.0 parts of hyaluronic acid and palmitoyl tetrapeptide bond, 0.1 part of seabuckthorn oil, 20.0 parts of emulsifier, 20.0 parts of sunflower oil, 15.0 parts of nicotinamide, 0.1 part of rose essential oil, 0.1 part of glycerin, and the balance is water.

Embodiment 3

[0040] A hyaluronic acid polypeptide bond mask, calculated by mass percentage, contains the following components:

[0041] 10.0 parts of hyaluronic acid and vascular endothelial growth factor bond, 5.0 parts of fruit acid, 11.0 parts of emulsifier, 10.5 parts of grape seed oil, 8.0 parts of D-pantothenic acid, 2.5 parts of chamomile essential oil, 5.0 parts of glycerin, and the balance is water. The mask has the function of improving microcirculation and anti-redness.

[0042] Wherein, the preparation steps of the bond between hyaluronic acid and vascular endothelial growth factor are:

[0043] Dissolve 1.0 g of hyaluronic acid with a molecular weight of 30,000 in 80 ml of PBS buffer solution (1.25%, w / v), adjust the pH to 7.0, add 200 mg of sodium periodate to open the ring, add 100 mg of vascular endothelial growth factor, and conjugate React for 8 hours to ensure that the reaction is complete; after purification by gel chromatography, freeze-dry, and confirm by NMR.

[00...

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Abstract

The invention discloses a hyaluronic acid-polypeptide bonded conjugate mask, which comprises the following ingredients (by weight): 0.1-20 parts of hyaluronic acid-polypeptide bonded conjugate, 0.1-10.0 parts of a skin whitening agent, 2.0-20.0 parts of an emulsifier, 0.5-20.0 parts of a cutin softener, 1.0-15.0 parts of a skin anti-wrinkling agent, 0.1-5.0 parts of a flavoring agent, 0.1-10.0 parts of glycerin and the rest of water. The mask composition contains polypeptide growth factors for preserving moisture, whitening, removing freckles, removing wrinkles and repairing scars, such as fibroblast growth factor, epithelial growth factor, vascular endothelial growth factor and the like. Those polypeptide growth factors and hyaluronic acid with low molecular weight are bonded and are released through a reversible chemical bond during the using process to be absorbed by face skin. Acting time is long, and cosmetic result is obvious.

Description

technical field [0001] The invention relates to the field of skin care products, in particular to a hyaluronic acid polypeptide bonded mask and a preparation method thereof. Background technique [0002] Mask is a commonly used skin care and beauty product at present. The principle is to use the short time covered on the face to temporarily isolate the outside air and pollution, increase the temperature of the skin, expand the pores of the skin, promote the secretion and metabolism of sweat glands, and make the skin more hydrated. The increase in oxygen level is beneficial for the skin to eliminate the products of epidermal cell metabolism and accumulated oily substances. The water in the mask penetrates into the stratum corneum of the skin epidermis, making the skin soft, naturally bright and elastic, achieving the effect of beauty and anti-aging. At present, there are many types of facial masks on the domestic market. Various ingredients in the facial masks, such as hyalur...

Claims

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Application Information

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IPC IPC(8): A61K8/73A61K8/97A61K8/92A61Q19/00A61Q19/02A61P17/00A61Q19/08
Inventor 王明慧邱岸
Owner 成都海卓派特科技有限公司
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