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Application of Torreya essential oil in the preparation of cosmetics and medicines against dermatophytes

A technology of dermatophytes and Torreya aril, applied in the field of natural medicinal chemistry, and can solve problems such as the application of essential oil of Torreya

Active Publication Date: 2020-08-04
KUNMING INST OF BOTANY - CHINESE ACAD OF SCI +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prior art, there is no application of Torreya essential oil in anti-dermatophytes

Method used

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  • Application of Torreya essential oil in the preparation of cosmetics and medicines against dermatophytes
  • Application of Torreya essential oil in the preparation of cosmetics and medicines against dermatophytes
  • Application of Torreya essential oil in the preparation of cosmetics and medicines against dermatophytes

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Distillation method and cold pressing method to extract the essential oil of fresh torreya arils:

[0021] Using the arils of fresh Torreya grandis cv Meorillii fruits as raw materials, it is the green casks of Torreya grandis cv Meorillii that can be stored for no more than 1 day at room temperature. The essential oil can be extracted from the arils of fresh Torreya grandis cv Meorillii. Double the water to distill in water for 2 to 4 hours, or use a screw cold press to extract the juice. After the obtained juice is centrifuged and precipitated by a centrifuge (the centrifuge speed is 5000 rpm, the time is 20 minutes), the supernatant is taken After distillation, the distillate is separated by an oil-water separator to obtain the essential oil of fresh torreya arils. The oil yield rate of the essential oil of torreya torreya obtained from fresh torreya arils is 0.35-0.45% (w / w, wet basis weight).

[0022] CO2 supercritical extraction of essential oil from fresh torreya ari...

Embodiment 2

[0030] The present invention uses the essential oil of torreya as the effective component of the anti-dermatophyte product. In order to confirm the anti-dermatophyte effect of the essential oil of torrenia of the present invention, the present invention has developed an anti-skin effect on the essential oil distilled from the arils of torrenia. The specific methods and results of the study of ringworm activity are as follows:

[0031] 1. Experimental strains

[0032] The in vitro antibacterial activity of Torreya essential oil The strains used in the study are mainly against 6 common pathogenic dermatophytes that cause tinea capitis, tinea corporis and a small number of onychomycosis: Microsporum canis, Microsporum gypsum, Microsporum rust , Trichophyton Ezerau, Trichophyton mentagrophytes, Epidermophyton flocculent.

[0033] 2. Experimental method

[0034] The minimum inhibitory concentration MIC test is slightly modified in accordance with clinical and laboratory standard documents...

Embodiment 3

[0041]

[0042] Preparation method: Add one ingredient at a time to the appropriate volume of redistilled water under stirring until it is completely decomposed, and then add another ingredient. After adding distilled water to 2ml, the solution was filtered on a sterile filter, filled into bottles and separated according to the appropriate dose.

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PUM

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Abstract

The invention belongs to the field of natural medicine and cosmetics, and provides application of Chinese torreya essential oil to preparation of anti-dermatophytes medicine, or application of Chinese torreya essential oil as efficiency ingredients in cosmetics for inhibiting the dermatophytes. In-vitro antibacterial activity study on the Chinese torreya essential oil shows that the Chinese torreya essential oil has better antibacterial activity on common pathogenic dermatophytes capable of causing tinea capitis, tinea corporis and little onychomycosis. The Chinese torreya essential oil is essential oil prepared from Chinese torreya aril by a distillation method, a cold squeezing method, a solvent extracting method or a carbon dioxide supercritical extraction method and the like. The Chinese torreya essential oil has the quality requirements that the Chinese torreya essential oil is colourless to yellowish Green liquid, and has the characteristic flavor of Chinese torreya fruit; the relative density (20 DEG C / 20 DEG C) is 0.850 to 0.860; the content sum of characteristic components of Alpha-pinene and limonene is greater than or equal to 30 percent. The invention discloses a new purpose of the Chinese torreya essential oil to prepare anti-dermatophytes medicine or cosmetics. In addition, an optimized preparation method of the Chinese torreya essential oil is provided by comparing the advantages and disadvantages of different extraction methods of the Chinese torreya essential oil.

Description

Technical field: [0001] The present invention relates to the field of natural medicine chemistry and cosmetics, in particular to the application of torreya essential oil extracted from torreya arils as raw materials in the preparation of anti-dermatophyte drugs and cosmetics. Background technique: [0002] Torreya grandis, also known as Torreya grandis, Torreya grandis, etc., is an evergreen tree of the genus Torreya in the Taxaceae family. It is an excellent variety cultivated by asexual reproduction from the natural variation within the species of Torreya grandis. It is distributed in my country's Zhejiang, Jiangsu, Anhui, Fujian and other provinces, the main producing areas are Zhuji, Shengzhou, Shaoxing, Dongyang, Pan'an and other places in the Kuaiji Mountain area of ​​Zhejiang Province. Torreya grandis is a multi-purpose precious tree that integrates edible, medicinal, oil, timber and ornamental greening. The fruit of Torreya grandis has always been favored and affirmed. Ho...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/13A61P17/00A61P31/10A61K8/92A61Q19/00
CPCA61K8/922A61K36/13A61Q19/00
Inventor 杜芝芝李志坚顾健龙赵云丽张红霞骆冠军
Owner KUNMING INST OF BOTANY - CHINESE ACAD OF SCI
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