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Functional toothpaste preparation for preventing and treating periodontitis

A functional periodontitis technology, applied in the field of medical supplies or health care daily chemicals, can solve the problems of imbalance, antibiotic abuse, oral flora, etc., and achieve the effect of reducing oral inflammation, good cell proliferation, and high application development value

Inactive Publication Date: 2016-08-03
THE AFFILIATED HOSPITAL OF QINGDAO UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide a functional toothpaste preparation for preventing and treating periodontitis and its application, so as to overcome the current problems of antibiotic abuse and the imbalance of oral flora caused by it.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Preparation of functional toothpaste preparation A: Weigh 0.5 g of antibacterial plant polypeptide, 2 g of zinc chloride, 2 g of glycerin, 1 g of sodium lauryl sulfate, 0.05 g of pigment, and 0.02 g of essence, disperse them in 50 mL of distilled water, stir to dissolve. Add 3 g of carboxymethyl cellulose and 2 g of sodium carboxymethyl cellulose to the solution, stir to thicken, and after stirring evenly, add 10 g of calcium carbonate, add distilled water to 100 g, stir evenly under a homogenizer, and vacuum degas to obtain the function toothpaste formulations.

[0019] In this embodiment, if it is stored or used for a long time, one or two mixtures of preservatives sodium benzoate or methyl paraben can be optionally added;

[0020] In this example, if it is applied to pregnant women or children, it is recommended not to add or reduce the use of raw materials such as pigments and flavors;

Embodiment 2

[0022] Preparation of functional toothpaste preparation B: Weigh 1 g of carboxymethyl chitosan, 2 g of zinc chloride, 2 g of glycerin, 1 g of sodium lauryl sulfate, 0.05 g of pigment, 0.02 g of essence, and 0.1 g of activated carbon, and disperse them in 50 mL of distilled water. Stir to dissolve. Add 1 g of hydroxyethyl cellulose and 2 g of sodium carboxymethyl cellulose to the solution, stir to thicken, and after stirring evenly, add 10 g of calcium carbonate, add distilled water to 100 g, stir evenly under a homogenizer, and vacuum degas to obtain the function toothpaste formulations.

[0023] In this embodiment, if it is stored or used for a long time, one or two mixtures of preservatives sodium benzoate or methyl paraben can be optionally added;

[0024] In this example, if it is applied to pregnant women or children, it is recommended not to add or reduce the use of raw materials such as pigments and flavors;

Embodiment 3

[0026] Preparation of functional toothpaste preparation C: Weigh 2 g of carboxymethyl chitin, 2 g of glycerin, 1 g of sodium lauryl sulfate, 0.05 g of pigment, 0.02 g of essence, and 1 g of diatomaceous earth, disperse them in 50 mL of distilled water, and stir to dissolve. Add 3g of hydroxyethyl chitosan and 2g of sodium carboxymethylcellulose to the solution, stir to thicken, and after stirring evenly, add 10g of calcium carbonate, add distilled water to 100g, stir evenly under a homogenizer, and vacuum degassing to obtain Functional toothpaste formulations.

[0027] In this embodiment, if it is stored or used for a long time, one or two mixtures of preservatives sodium benzoate or methyl paraben can be optionally added;

[0028] In this example, if it is applied to pregnant women or children, it is recommended not to add or reduce the use of raw materials such as pigments and flavors;

[0029] In this embodiment, the active substance can be one or more of plant polypeptide...

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PUM

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Abstract

The invention discloses a functional toothpaste preparation for preventing and treating periodontitis. The functional toothpaste preparation comprises the following components in parts by weight: 5-25 parts of an abrasive, 1-5 parts of a humectant, 1-3 parts of a surface active agent, 2-10 parts of thickener, 0-0.5 part of a preservative, 1-5 parts of an active material, 0-2 parts of a pigment, 0-2 parts of essence and distilled water added to 100 parts. According to the functional toothpaste preparation for preventing and treating periodontitis, functional materials of carboxymethyl chitosan, carboxymethyl chitin and the like with injured tissue repair promoting action are adopted; bacteria adhesion is prevented; the active materials of antibacterial plant polypeptide and the like for oral periodontitis pathogenic bacteria growth are inhibited; the preparation does not contain a pharmaceutical ingredient; imbalance of normal flora in the oral cavity is avoided; compared with traditional toothpaste, the functional toothpaste preparation has the effects of preventing and treating a periodontal disease; compared with the medicine for treating periodontitis, the functional toothpaste preparation has the characteristics of being mild, safe, lasting, effective and the like, and is an excellent oral heath product; the medicine resistance is not easy to generate; and tooth stone formation is relieved.

Description

technical field [0001] The invention belongs to the field of medical supplies or health care daily chemicals, and relates to a functional toothpaste preparation for preventing and treating periodontitis. Background technique [0002] Periodontitis is a common oral disease. Its main cause is bacterial infection. Bacteria accumulate on the tooth surface and gingival sulcus in the form of plaque. Microorganisms and their metabolites stimulate periodontal tissue and cause periodontitis. Its main symptoms are bleeding gums, swelling, suppuration, receding gums, loose teeth or even loss of teeth, resulting in tooth loss, affecting chewing and digestive functions. The disease can also be used as an infection lesion to cause or aggravate certain systemic diseases, such as diabetes , cardiovascular disease, infective endocarditis, respiratory disease, etc., have great harm to health. [0003] The main measures for the prevention and treatment of periodontitis are oral antibacterial,...

Claims

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Application Information

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IPC IPC(8): A61K8/73A61K8/64A61K8/27A61K8/19A61K8/96A61Q11/00A61K38/02A61K31/722A61K33/30A61K33/24A61K33/00A61K35/02A61P1/02
CPCA61K8/19A61K8/27A61K8/645A61K8/736A61K8/965A61K31/722A61K33/00A61K33/24A61K33/30A61K35/02A61K38/02A61Q11/00A61K2300/00
Inventor 邓婧潘克清袁昌青吉秋霞刘梦冬孙培徐全臣于新波
Owner THE AFFILIATED HOSPITAL OF QINGDAO UNIV
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