Device and method for detecting effect of harringtonine cancer treatment

A technology for harringtonine cancer and harringtonine cancer, which is applied in the field of devices for detecting the therapeutic effect of harringtonine cancer, and can solve problems such as patient physical injury, toxic reactions, failure to achieve therapeutic effects, etc. safe effect

Active Publication Date: 2018-04-10
HANGZHOU RED CROSS HOSPITAL
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] There is no clinical data to refer to the efficacy of new anti-cancer drugs. In the initial use, it is entirely dependent on the doctor's exploration and judgment. If the dose is insufficient, the therapeutic effect will not be achieved; Patient's bodily harm

Method used

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  • Device and method for detecting effect of harringtonine cancer treatment
  • Device and method for detecting effect of harringtonine cancer treatment
  • Device and method for detecting effect of harringtonine cancer treatment

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Embodiment Construction

[0060] The present invention will be further described below in conjunction with the accompanying drawings and specific embodiments.

[0061] Such as figure 1 , image 3 The illustrated embodiment is a detection device for the treatment effect of harringtonine cancer, including an operating platform 1, an electrochemical workstation 2, 3 flow cells 3, and a first solution bottle filled with cleaning solution on the operating platform. 4 and the second solution bottle 5 filled with harringtonine solution; each flow cell is provided with a substrate 6, and each substrate is provided with an electrode chip 7; the cover plates of the first solution bottle and the second solution bottle All are provided with catheter, the catheter of the second solution bottle is provided with the first micropump 9, the catheter of the first solution bottle is provided with the second micropump 10, the first micropump and the second micropump The liquid outlets are all connected to the liquid col...

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Abstract

The invention discloses a detection apparatus and method for cancer treatment effect of harringtonine. According to the invention, the peak value of the signal-to-noise ratio of harringtonine with unknown drug effect is compared with the peak value of the signal-to-noise ratio of a frequently used cancer treatment drug, i.e., cisplatin, and the drug effect and dosage of harringtonine are obtained in comparison with the known drug effect and dosage of cisplatin. The detection apparatus and method provided by the invention have the characteristics of high detection efficiency, good accuracy and capacity of providing reliable bases for safe usage of harringtonine so as to ensure safety of patients.

Description

technical field [0001] The invention relates to the technical field of drug efficacy detection, in particular to a device and method for detecting the efficacy of harringtonine cancer treatment that can accurately detect drug efficacy. Background technique [0002] The dosage of anticancer drugs must be accurate, and when the dosage is insufficient, the therapeutic effect will not be achieved. When the dose exceeds the safe dose, it will cause gastrointestinal reactions such as loss of appetite, nausea, vomiting, and diarrhea. The common and serious toxic reaction is nephrotoxic reaction. Repeated medication can aggravate nephrotoxic reaction, mainly damage the proximal convoluted tubule of the kidney, cause cell vacuolation, epithelial shedding, lumen dilation, hyaline casts, and excessive uric acid in the blood. In severe cases, it can cause symptoms such as hematuria. [0003] When used in large doses and repeatedly, neurotoxic reactions will occur, which will damage th...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N27/416
CPCG01N27/416
Inventor 万海方陶凡
Owner HANGZHOU RED CROSS HOSPITAL
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