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Sambucus adnata hard ointment capable of diminishing inflammation and relieving pain and preparation method thereof

An anti-inflammatory, pain-relieving, blood-filled grass technology, applied in the direction of ointment delivery, non-central analgesics, anti-inflammatory agents, etc., can solve the problems of inconvenient use, achieve the effects of avoiding direct contact, enhancing the effect, and simple preparation method

Inactive Publication Date: 2016-09-21
YUNNAN UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] Aiming at the deficiencies of the prior art, the present invention provides a hard ointment with the extract of Herba Cauliflower as the active ingredient, which has the effects of reducing swelling, dispelling blood stasis, relaxing tendons, activating collaterals, and relieving pain, and overcomes the inconvenient use of the ointment in the prior art. Convenience and other defects, enhance the effect of drugs

Method used

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  • Sambucus adnata hard ointment capable of diminishing inflammation and relieving pain and preparation method thereof

Examples

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Effect test

Embodiment 1

[0024] An anti-inflammatory and analgesic hard ointment of Xuemancao, which consists of the following components in parts by mass: 1% of Xuemancao extract, 1.5% of potassium myristate, 80% of ethanol, 0.5% of polyethylene glycol, and camphor extract 2%, stearyl polydimethylsiloxane 10%, pentaerythritol tetraisostearate 5%.

[0025] The preparation method of described Xuemancao anti-inflammatory and pain-relieving hard ointment comprises the following steps:

[0026] (1) remove the root of the Herba Cerulea and pulverize it, add 5 times the amount of ethanol solution, and heat to reflux to obtain the Herba Cerulea extract;

[0027] (2) After mixing stearyl polydimethylsiloxane, pentaerythritol tetraisostearate and potassium myristate evenly, heat up to 50°C, add ethanol and polyethylene glycol, and stir continuously to obtain an ointment matrix;

[0028] (3) Dispersing and diluting the extracts of Xuemancao and traditional Chinese medicine, and then adding them into the ointm...

Embodiment 2

[0031] An anti-inflammatory and analgesic hard ointment of Xuemancao, which consists of the following components in parts by mass: 1% of Xuemancao extract, 10% of sodium palmitate, 20% of sodium stearate, 30% of methanol, 0.5% of propylene glycol, Camphor extract 2%, synthetic squalane 20%, petrolatum 17.5%;

[0032] The preparation method of described Xuemancao anti-inflammatory and pain-relieving hard ointment comprises the following steps:

[0033] (1) remove the root of the Herba Cerulea and pulverize it, add it to an aqueous solution of 10 times the amount, and extract the Herba Cerulea extract by ultrasonication;

[0034] (2) Mix synthetic squalane and petrolatum with sodium palmitate and sodium stearate evenly, heat up to 60°C, add methanol and propylene glycol, and keep stirring to obtain an ointment base;

[0035] (3) Dispersing and diluting the extracts of Xuemancao and traditional Chinese medicine, and then adding them into the ointment base cooled to 38-40°C, and ...

Embodiment 3

[0038] An anti-inflammatory and analgesic hard ointment of Xuemancao, which consists of the following components in parts by mass: 2% of Xuemancao extract, 10% of sodium linoleate, 5% of capric acid, 50% of isopropanol, glycerol Alcohol 10%, Peppermint Extract 3%, Tridecyl Trimellitate 5%, Petrolatum 15%.

[0039] The preparation method of described Xuemancao anti-inflammatory and pain-relieving hard ointment comprises the following steps:

[0040] (1) Remove the roots of the Herba Cerulea and pulverize it, add 8 times the amount of water and ethanol to the mixed solution, and extract the Herba Cerulea extract by solvent soaking method;

[0041] (2) Mix tridecyl trimellitate, petrolatum and sodium linoleate evenly, heat up to 70°C, add isopropanol and glycerin, and stir continuously to obtain an ointment base;

[0042] (3) Dispersing and diluting the extracts of Xuemancao and traditional Chinese medicine, and then adding them into the ointment base cooled to 38-40°C, and stir...

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Abstract

The invention discloses a sambucus adnata hard ointment capable of diminishing inflammation and relieving pain and a preparation method thereof, and relates to the technical field of application of natural plant extract in the field of medicine. The sambucus adnata hard ointment capable of diminishing inflammation and relieving pain is prepared from, by mass, 1-30% of sambucus adnata extract, 1-30% of fatty acid alkali metal salt, 10-80% of monohydric alcohol, 0.5-50% of polyhydric alcohol, 2-10% of an auxiliary material and 15-40% of aids. The hard ointment is mainly used for treating traumatic injuries, sprains and mild water or fire scalds, is definite in treatment effect, prolongs the action time of active ingredients on affected parts and increases the utilization rate of active ingredients on affected parts, and the action effect of medicine is enhanced; besides, the preparation method of the hard ointment is simple and has the advantages that temperature control is easy, grinding is not needed, the character is good and preparation is easy, and the preparation method is especially suitable for large-scale industrial production.

Description

technical field [0001] The invention relates to the technical field of application of natural plant extracts in the field of medicine, in particular to a hard ointment for anti-inflammatory and analgesic effects of Xuemancao and a preparation method thereof. Background technique [0002] At present, anti-inflammatory and analgesic drugs widely used clinically for bruises, sprains, muscle pain, joint pain, fracture pain and other diseases can generally be divided into oral and external dosage forms. Common external dosage forms include ointment, liniment and patch, etc., but it is worth noting that when the viscosity of the external anti-inflammatory and pain-relieving gel (thickening agent) is less than 5000cps, its coating effect on the skin of the diseased part is not ideal, and the viscosity exceeds 5000cps. 35000cps is not suitable for use, and the interfacial tension is less than 5dyn / cm 2 The gel solution will flow out of the application surface. In addition, for the...

Claims

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Application Information

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IPC IPC(8): A61K36/35A61K9/06A61K47/10A61P29/00A61P17/02
CPCA61K36/35A61K9/0014A61K9/06A61K47/10A61K2236/331A61K2236/333
Inventor 王葳王文静李维熙吕小满刘冬丽陈飞龙李荣姣薛咏梅
Owner YUNNAN UNIV OF TRADITIONAL CHINESE MEDICINE
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