Concentration gradient generator capable of generating any linear and secondary curve profile

Abstract

The invention discloses a concentration gradient generator capable of generating any linear or secondary curve profile. The concentration gradient generator has a simple pipeline connecting structure. When the concentration gradient generator comprises two inlet ends, four layers of branch channels are formed correspondingly; when the concentration gradient generator comprises three inlet ends, three layers of branch channels are formed correspondingly; the branch channels are connected through transverse channels and vertical channels respectively; the inner diameter size of a pipeline needs to be 0.1mm-0.2 mm. By adopting the concentration gradient generator, controllability of a concentration gradient shape is realized, concentration gradient shapes at two inlet-end concentration gradient generator outlets present certain angle changes by adjustment of the flow speed of a solution, and the peak values of concentration gradient shapes at outlets of the three-inlet-end concentration gradient generator present certain concentration changes. The concentration gradient generator has great significance to the research of cell tropism in bioengineering and chemical engineering.

Description

technical field [0001] The invention belongs to the technical field of microfluidic chips, and in particular relates to a concentration gradient generator capable of generating arbitrary linear and quadratic curve profiles. Background technique [0002] The microfluidic chip is an interactive integrated micro-full analysis system. The microfluidic chip has begun to move from the laboratory to the application, which is of great significance to the research and industrialization of the microfluidic chip. The concentration gradient generator is a further application of the microfluidic chip. Organisms can sense a variety of chemical molecular signals in the surrounding environment and change their physiological activities according to the chemical concentration gradient. Using microfluidic chips to simulate the external environment and establish the concentration gradients required for the research of different organisms plays an important role in the fields of drug screening,...

AI Technical Summary

Problems solved by technology

At present, there is no concentration gradient generator that can systematically provide different shapes of concentration gradients at different flow rates, so that the desired concentration gradient can be achieved by controlling the flow rate

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