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Application of forsythin, its derivatives, and forsythin/forsythin composition in the preparation of medicines for treating bacterial infections

A technology of forsythin derivatives and forsythiatin, applied in the field of medicine, can solve problems such as drug resistance, achieve quick results, rich sources of raw materials, and good medicinal prospects

Active Publication Date: 2019-07-26
富力
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the most conspicuous problem in Gram-negative bacilli is that bacteria are resistant to third-generation cephalosporins and new broad-spectrum-lactam antibiotics, and the main mechanism is that bacteria produce extended-spectrum-lactamase ( extended spectrum-laetamases, ESBLs) lead to bacterial resistance to third-generation lactam antibiotics and aztreonam

Method used

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  • Application of forsythin, its derivatives, and forsythin/forsythin composition in the preparation of medicines for treating bacterial infections
  • Application of forsythin, its derivatives, and forsythin/forsythin composition in the preparation of medicines for treating bacterial infections
  • Application of forsythin, its derivatives, and forsythin/forsythin composition in the preparation of medicines for treating bacterial infections

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Example 1 Forsythin Tablets

[0040] 1. Prepare raw materials according to the following ratio

[0041]

[0042] 2. Mix forsythin and starch evenly to make granules, add talcum powder and magnesium stearate, mix evenly, and press to make 10,000 tablets.

Embodiment 2

[0043] Example 2 Forsythin Capsules

[0044] 1. Prepare raw materials according to the following ratio

[0045] Forsythin (purity 94%) 200g

[0046] Starch 1000g

[0047] 2. Mix forsythin and starch evenly and pack into capsules to make 10,000 capsules.

Embodiment 3

[0048] Example 3 Forsythin Capsules

[0049] 1. Prepare raw materials according to the following ratio

[0050] Forsythin (purity 98%) 500g

[0051] Starch 1000g

[0052] 2. Mix forsythin and starch evenly and pack into capsules to make 10,000 capsules.

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PUM

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Abstract

Provided is a use of forsythin, derivatives thereof and a composition of forsythin / forsythiaside in the preparation of a drug for treating bacterial infections. Experiments have proven that the efficacy of forsythin, forsythin derivatives, the composition of forsythin and forsythiaside for treating bacterial infections is significant, quick, has few toxic side effects, and is a safe, efficient, stable drug with a simple preparation process for treating bacterial infections, is suitable for industrial production, easily popularized, and provides a new drug source for preventing, relieving and treating bacterial infections and the complications thereof.

Description

technical field [0001] The invention relates to the field of medicine, and relates to a medicine or health food for treating bacterial infection, in particular to an application of traditional Chinese medicine forsythia and forsythia leaf extract components in medicine or health food for alleviating and / or treating bacterial infection. Background technique [0002] Antibiotic resistance has become a worrying and widespread problem worldwide, leading to rising morbidity and mortality associated with infectious diseases and their treatment costs, and bacterial resistance to emerging antimicrobials. The cycle of drug resistance is getting shorter and shorter, which has become a major problem for clinicians. How to solve the problem of antibiotic resistance is an important issue that researchers and clinicians cannot avoid. Bacterial resistance to -lactam antibiotics is the most common and important type of antibiotic resistance. At present, the most conspicuous problem in Gram...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7048A61K36/19A61K36/35A61K36/539A61K36/288A61K36/315A61K36/71A61K36/78A61K36/489A61K36/9062A61P31/04A23L33/10A23L33/105A61K31/34A61K31/375A61K31/355
CPCA61K36/634
Inventor 王凯乾富力惠敏鲁明明刘正贤王硕付强刘国友
Owner 富力
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