Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Preparation method of magnesium L-threonate

A technology of magnesium threonate and reaction time, which is applied in the chemical industry and can solve the problems of low yield

Active Publication Date: 2016-11-09
ZHANG JIA GANG VINSCE BIO PHARM
View PDF4 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The resulting product has higher purity, but the yield is not high

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method of magnesium L-threonate

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Dissolve 0.1mol of vitamin C in 500ml of water, stir to dissolve at room temperature, control the temperature, add 0.06mol of magnesium hydroxide to neutralize, then add 0.25mol of magnesium peroxide; After adding peroxidase to the solution, react at a temperature of 35°C for 0.5h; filter with suction, concentrate the filtrate to thick, add 90% aqueous ethanol solution dropwise to the concentrated solution, and let it stand for crystallization under temperature control; filter with suction to obtain L- Magnesium threonate crystals weighed 12.54g after drying, with a yield of 65% and a purity of 98.5%.

Embodiment 2

[0024] Dissolve 0.1mol vitamin C in 500ml water, stir to dissolve at room temperature, control temperature, add 0.06mol magnesium hydroxide to neutralize, then add 0.20mol magnesium peroxide; keep stirring, react at room temperature for 6h; After the oxidase, react at a temperature of 35°C for 0.5h; filter with suction, concentrate the filtrate until thick, add 90% aqueous ethanol solution dropwise to the concentrated solution, and crystallize under temperature control; filter with suction to obtain magnesium L-threonate After drying, the crystal weighed 11.48g, the yield was 59.5%, and the purity was 97.2%.

Embodiment 3

[0026] Dissolve 0.1mol vitamin C in 500ml water, stir to dissolve at room temperature, control temperature, add 0.05mol magnesium hydroxide to neutralize, then add 0.30mol magnesium peroxide; continue stirring, control temperature at 50°C for 3.5h; After adding peroxidase to the solution, react at a temperature of 35°C for 0.5h; filter with suction, concentrate the filtrate to thick, add 95% aqueous ethanol solution dropwise to the concentrated solution, and let it stand for crystallization under temperature control; filter with suction to obtain L- Magnesium threonate crystals weighed 11.81g after drying, with a yield of 61.2% and a purity of 97.0%.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides an industrial preparation method of magnesium L-threonate. According to the method, vitamin C is taken as a raw material, dissolved in a water solution and reacted with magnesium peroxide as an oxidizing agent, then peroxidase is added to a reaction system, residual oxidizing agent is removed, an ethanol water solution is used for crystallization, and magnesium L-threonate is prepared through normal-temperature crystal separation. The preparation method is screened out through process optimization, can be applied to industrial production, adopts a simple process and mild conditions, and is easy to operate and master, high in yield, environment-friendly and lower in cost.

Description

technical field [0001] The invention relates to a preparation method of magnesium L-threonate, which belongs to the field of chemical industry. Background technique [0002] Magnesium L-threonate is a food additive, which belongs to four-carbon polyhydroxy compounds, and is an efficient and safe magnesium nutritional supplement. Magnesium threonate is easier to metabolize and absorb in the human body than inorganic magnesium. Since L-threonate is a metabolite of L-ascorbic acid, it is safer when applied to the human body. Magnesium L-threonate can participate in the mediation of neuron activity, maintain the normal operation of cardiovascular, neuromuscular and nervous systems, and effectively improve magnesium deficiency and a series of related symptoms. Due to its high-efficiency biological activity and high safety, its research is more active and its application is more extensive. [0003] The synthesis of L-magnesium threonate has been reported in Chinese patent 991238...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C07C51/41C07C59/10
CPCC07C51/41C07C59/10
Inventor 彭学东张梅赵金召闫勇义弓旻
Owner ZHANG JIA GANG VINSCE BIO PHARM
Features
  • Generate Ideas
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com