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Pharmaceutical composition for increasing bone density and preparation method thereof

A technology for increasing bone density and composition, which is applied in the field of pharmaceutical composition for increasing bone density and its preparation, can solve problems such as increasing bone density, and achieve the effects of increasing bone density, increasing bone calcium content, and inhibiting bone resorption

Active Publication Date: 2017-01-11
湖南知达医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Sodium vitamin C phosphate is a derivative of vitamin C. It is a new type of food additive. Vitamin C can be liberated by phosphatase enzymolysis in the body, and the unique physiological functions of vitamin C can be exerted. It can be used to prevent and treat scurvy and relieve white vitiligo. and other diseases, there is currently no relevant research showing that vitamin C phosphate sodium has the effect of increasing bone density

Method used

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  • Pharmaceutical composition for increasing bone density and preparation method thereof
  • Pharmaceutical composition for increasing bone density and preparation method thereof
  • Pharmaceutical composition for increasing bone density and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Embodiment 1 increases the preparation of the pharmaceutical composition of bone mineral density and its granule

[0045] The pharmaceutical composition for increasing bone density in Example 1 of the present invention includes the following preparation raw materials in parts by weight: 3 parts of oysters, 1 part of malt, 2 parts of Chinese yam, 1 part of poria cocos, 2 parts of jujube, 1 part of licorice, and 1 part of gallinaceous gold servings, vitamin D 2 0.0000025 parts, 12 parts of calcium gluconate, 20 parts of isomaltooligosaccharide, 5 parts of citric acid, 45 parts of cyclodextrin.

[0046] Preparation of the pharmaceutical composition:

[0047] (1) Take malt, Chinese yam, poria cocos, jujube, gallinacea and licorice, dry and crush, pass through an 80-mesh sieve, add 8 times the total weight of medicinal materials and soak for 1 hour, and reflux extraction twice, each time for 4 hours, Filter and retain the filter residue, combine the filtrate to obtain the...

Embodiment 2

[0053] Embodiment 2 increases the preparation of the pharmaceutical composition of bone mineral density and its granule

[0054] The pharmaceutical composition for increasing bone density in Example 2 of the present invention includes the following preparation raw materials in parts by weight: 6 parts of oysters, 0.5 parts of malt, 4 parts of Chinese yam, 1 part of poria cocos, 1 part of Chinese jujube, 0.5 part of licorice, and 2 parts of gallinaceous gold servings, vitamin D 2 0.000001 parts, 15 parts of calcium gluconate, 15 parts of glucose, 5 parts of citric acid, 40 parts of starch.

[0055] The preparation of the pharmaceutical composition refers to Example 1.

[0056] The preparation of granules refers to Example 1.

Embodiment 3

[0057] Embodiment 3 increases the preparation of the pharmaceutical composition of bone mineral density and its granule

[0058] The pharmaceutical composition for increasing bone density in Example 3 of the present invention includes the following preparation raw materials in parts by weight: 2 parts of oysters, 2 parts of malt, 1 part of Chinese yam, 3 parts of poria cocos, 4 parts of jujube, 2 parts of licorice, 0.5 parts of gallinaceous servings, vitamin D 2 0.000005 parts, 5 parts of calcium gluconate, 10 parts of white sugar, 5 parts of citric acid, 50 parts of mannitol.

[0059] The preparation of the pharmaceutical composition refers to Example 1.

[0060] The preparation of granules refers to Example 1.

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Abstract

The invention belongs to the field of health products and in particular relates to a pharmaceutical composition for increasing bone density and a preparation method thereof. The pharmaceutical composition provided by the invention is prepared from the following raw materials in parts by weight: 2-6 parts of oysters, 0.5-2 parts of malt, 1-4 parts of Chinese yams, 1-3 parts of poria cocos, 1-4 parts of Chinese dates, 0.5-2 parts of liquorice, 0.5-2 parts of endothelium corneum gigeriae, 0.000001-0.000005 part of vitamin D2, 5-15 parts of calcium gluconate, 2-5 parts of sodium L-ascorbic-acid-2-phosphate, 1-4 parts of glutathione, 1-4 parts of phellinus igniarius fermented powder and 2-75 parts of auxiliary materials. The pharmaceutical composition provided by the invention has a good calcium supplementing effect, is rich in nutritional ingredients, safe and effective, convenient to take and applicable to being taken by children for a long time and can promote sustainable growth of the bone density.

Description

technical field [0001] The invention belongs to the field of health care products, and in particular relates to a pharmaceutical composition for increasing bone density and a preparation method thereof. Background technique [0002] Osteoporosis is a systemic change in bone mass and bone tissue structure, accompanied by increased bone fragility and easy to cause fractures. It is characterized by decreased number of beams, widened bone marrow cavity, decreased bone strength, and susceptibility to fracture. [0003] Bone mineral density is an important indicator for the diagnosis of osteoporosis and is used by the World Health Organization to define the diagnostic criteria for osteoporosis. Bone density refers to the bone mineral content per unit area of ​​bone. The more bone mineral is deposited in the bone, the greater the bone density and the stronger the bone. From infancy, childhood to adolescence, the bone formation of osteoblasts is greater than the bone resorption o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8998A61K38/06A61P19/10A61P3/02A61K31/191A61K31/592A61K31/661A61K35/57A61K35/618
CPCA61K31/191A61K31/592A61K31/661A61K35/57A61K35/618A61K36/07A61K36/076A61K36/484A61K36/725A61K36/8945A61K36/8998A61K38/06A61K2236/19A61K2236/331A61K2236/333A61K2236/39A61K2300/00
Inventor 卞国良李君佩赵振伟
Owner 湖南知达医药科技有限公司
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