Compound dressing with high liquid absorption performance and preparation method of compound dressing

Abstract

The invention relates to compound dressing with high liquid absorption performance and a preparation method of the compound dressing. The compound dressing is prepared from chitosan serving as a raw material and consists of a supporting layer and a functional layer, wherein the supporting layer is functional nonwoven cloth; the functional layer is prepared by performing water dissolving, macromolecular crosslinking, foaming, freeze drying and the like on carboxymethyl chitosan. The compound dressing is high in mechanical property and pore-forming property; furthermore, by the compound design of a dual-layer structure, the liquid absorption performance is higher than that of common dressing, and the compound dressing is suitable for perpendicular absorption application. Chitosan is a natural macromolecular polymer and belongs to aminopolysaccharide, so that the dressing is high in mechanical property, high in seepage absorption, and also high in biological compatibility, degradability and nontoxicity, can induce tissue regeneration and remodeling, can effectively promote healing of a wound, and is a more ideal healing promotion material.

Description

technical field [0001] The invention belongs to the field of medical devices, and relates to a composite dressing and a production process thereof, in particular to a non-woven dressing made of chitosan and cotton polysaccharide as raw materials, which is suitable for tissue repair with high mechanical strength and high liquid absorption. A biomedical material, the dressing is suitable for covering and treating burn wounds, trauma wounds, chronic ulcer wounds, decubitus wounds, infected wounds, and surgical wounds. Background technique [0002] Medical dressings are a class of clinical medical materials that temporarily cover burns, ulcers, wounds and other wounds. Its main function is to control the exudate of the wound and protect the wound from external sources such as bacteria and dust particles. With the accelerated pace of modern life and the increasing demand for medical care, the demand for medical dressings is also increasing year by year. From a global perspective,...

AI Technical Summary

Problems solved by technology

Chitosan often faces several difficulties in the preparation of dressings, such as solubility, liquid absorption, bacteriostasis, comfort, etc. Although some patents have shown some research results, it is obvious that it needs to be studied as a large-scale production process, such as In Chinese patent CN 101816802 A, a chitosan-based medical dressing is prepared, but because the film formed by them is brittle and has poor mechanical properties, it is often necessary to improve its mechanical properties by blending with other materials; invention patent CN1431021A Disclosed is a chitosan-collagen sponge used for gynecological diseases. In the preparation process, acidic solutions such as hydrochloric acid or acetic acid are used to dissolve chitosan, and the acidic solution is used, which is likely to cause adverse effects on the environment and requires secondary vacuum freezing Drying increases cost; invention patent CN105477679 A discloses a preparation method of chitosan rapid hemostatic cotton based on polysaccharide crosslinking. Polysaccharide is poor, so it can only be used as a hemostatic material

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