Biological buffering bicarbonate tablet and preparation method thereof

Abstract

The invention relates to a biological buffering bicarbonate tablet and a preparation method thereof. The preparation method comprises the following steps: (1) accurately weighing sodium carbonate, sodium bicarbonate, cross-linked amylose and sodium azide; (2) uniformly mixing the above components under stirring; (3) pressing the components into a tablet on a tablet press; and (4) carrying out weighing and testing to obtain qualified tablets, and then carrying out packaging; wherein the pressure of the tablet press is five tons. The round tablet prepared in the invention can be directly used immediately after opening of package, is simple to use, substantially mitigates labor intensity of users, saves working time and improves working efficiency; in usage, the tablet can be rapidly dissolved after addition into a solvent with a fixed volume, so a desired buffer solution with an accurate and stable pH value can be obtained; and the tablet is easy to preserve and transport, long in preservation time, simple and rapid to prepare and suitable for industrial processing.

Description

technical field [0001] The invention belongs to the technical field of chemical reagents, and relates to auxiliary reagents used in biological, medical and chemical experiments, in particular to a bicarbonate biological buffer tablet and a preparation method thereof. Background technique [0002] A buffer solution is a solution that greatly reduces changes in pH when small amounts of acid or base and water are added. The pH buffer system plays a major role in maintaining the normal pH value and normal physiological environment of organisms. Most cells can only operate within a narrow pH range and require buffer systems to resist pH changes during metabolism. There are three main pH buffer systems in living organisms, mainly protein buffer system, bicarbonate buffer system and phosphate buffer system. The amount of each buffer system is different in various cells and organs. In biochemical research, it is often necessary to use buffer solutions to maintain the pH of the ex...

AI Technical Summary

Problems solved by technology

But when the pH buffer solution is prepared, because of the quality problems of sodium carbonate and sodium bicarbonate, the pH value must be strictly adjusted with a pH meter when preparing each time, which is time-consuming and labor-intensive. The present invention is directly made into tablets, and the pH value is strictly controlled. It can be added directly when it is time-saving and accurate. At present, there is no such product in China, and imported products are expensive.