Aminocyclodextrin, and preparation method and application thereof
A cyclodextrin and amine-based technology, applied in the field of cyclodextrin, achieves the effects of mild reaction conditions, simple process, and good inhibitory performance
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[0032] The present invention provides a method for preparing the aminocyclodextrin described in the above technical scheme, comprising:
[0033] The β-cyclodextrin solution, the chlorinated epoxide and the acidic catalyst are reacted to obtain an intermediate product, and the β-cyclodextrin has the structure shown in formula III:
[0034]
[0035] The chlorinated epoxides include epichlorohydrin or 1,2-epoxychlorobutane;
[0036] The intermediate product is reacted with an organic amine to obtain an amino cyclodextrin; the organic amine includes ethylenediamine, diethylenetriamine, triethylenetetramine, tetraethylenepentamine or pentaethylenehexamine.
[0037] In an embodiment of the present invention, the reaction temperature of the β-cyclodextrin solution, the chlorinated epoxide and the acidic catalyst is 95° C. to 150° C.; in other embodiments, the β-cyclodextrin solution , the reaction temperature of the chlorinated epoxide and the acidic catalyst is 110°C to 140°C; ...
Embodiment 1
[0065] Add 140g of β-cyclodextrin into 200g of water, stir and heat to 80°C to fully dissolve the cyclodextrin to obtain a β-cyclodextrin solution;
[0066] Add 70g of epichlorohydrin and 8g of sulfuric acid to the above-mentioned β-cyclodextrin solution, and react at a temperature of 95°C for 3.0h to obtain an intermediate product;
[0067] Add 60 g of ethylenediamine to the above intermediate product, stir and mix evenly, react at a temperature of 60° C. for 3.0 h, dry the obtained reaction product to remove water, and obtain amino cyclodextrin with a yield of 96.52%.
[0068] The aminocyclodextrin prepared in Example 1 of the present invention has the structure shown in Formula 1:
[0069]
[0070] In formula 1, R is:
[0071]
[0072] Wherein, m is 1, and n is 0.
[0073] According to the method described in the above technical scheme, the primary recovery rate of shale, the relative recovery rate of shale, and the extreme pressure lubrication coefficient of the am...
Embodiment 2
[0075] Add 160g of β-cyclodextrin into 210g of water, stir and heat to 80°C to fully dissolve the cyclodextrin to obtain a β-cyclodextrin solution;
[0076] Add 80g of 1,2-epoxychlorobutane and 9g of p-toluenesulfonic acid to the above β-cyclodextrin solution, and react at a temperature of 100°C for 4.0h to obtain an intermediate product;
[0077] Add 70 g of diethylenetriamine to the above intermediate product, stir and mix evenly, react at a temperature of 70° C. for 4.0 h, dry the obtained reaction product to remove water, and obtain amino cyclodextrin with a yield of 97.32%.
[0078] The aminocyclodextrin prepared in Example 2 of the present invention has the structure shown in formula 2:
[0079]
[0080] In formula 2, R is:
[0081]
[0082] Wherein, m is 2, and n is 1.
[0083] According to the method described in the above technical scheme, the primary recovery rate of shale, the relative recovery rate of shale, and the extreme pressure lubrication coefficient ...
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