Compositions comprising melatonin and flavonoids for use in the treatment of tumours resistant to chemotherapy

A technology of melatonin and composition, which is applied in the field of flavonoid composition, can solve problems such as the activity of chemically resistant cells that are not mentioned
CN106535939AInactive Publication Date: 2017-03-22PROBIOTICAL
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
PROBIOTICAL
Publication Date
2017-03-22
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention relates to compositions comprising at least one flavonoid of natural or synthetic origin in association with melatonin for use to increase the effectiveness of chemotherapeutic treatments used in human and veterinary medicine for the treatment of tumours, in particular for the treatment of tumours resistant to the chemotherapeutic agents currently in use. The at least one flavonoid is selected from the group comprising or, alternatively, consisting of rutin, oxerutin, diosmin and hesperidin, preferably rutin.
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Description

Contents of the invention

[0001] The present invention relates to a composition comprising at least one flavonoid of natural or synthetic origin in combination with melatonin, for enhancing the efficacy in human and veterinary medicine for the treatment of tumors, in particular for the treatment of those resistant to currently used chemotherapeutic agents. Effectiveness of chemotherapeutic treatment of resistant tumors; said at least one flavonoid is selected from the group comprising or consisting of rutin, oxerutin, diosmin and hesperidin, preferably rutin.

[0002] Background of the invention

[0003] Currently, tumor cell resistance to chemotherapeutic treatment represents a continuously evolving problem of enormous proportions. Drug resistance manifests itself in both solid tumors and tumors of the lymphatic system, and can emerge from the start of therapy or after an initial positive response to therapy. For example, many times chemotherapy resistance manifests itself...

Claims

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