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A real-time monitoring system and monitoring method for serological indicators of amniotic fluid embolism

A real-time monitoring system and serological index technology, applied in the direction of measuring devices, scientific instruments, instruments, etc., can solve the problems of long time-consuming, cumbersome procedures, large sampling volume, etc., and achieve the effect of short time-consuming and low measurement sampling volume

Active Publication Date: 2018-09-04
广东省安家医健健康管理有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current detection method for ZnCp-I in blood is to perform centrifugation and high-performance liquid chromatography on blood samples, and then perform induced fluorescence detection (the wavelength of excitation light is 405nm, and the wavelength of detection fluorescence is 580nm). Large amount, time-consuming, and cumbersome procedures, which are not suitable for close monitoring requirements

Method used

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  • A real-time monitoring system and monitoring method for serological indicators of amniotic fluid embolism
  • A real-time monitoring system and monitoring method for serological indicators of amniotic fluid embolism
  • A real-time monitoring system and monitoring method for serological indicators of amniotic fluid embolism

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Embodiment 1

[0026] see figure 1 , which is a structural schematic diagram of the real-time monitoring system for serological indicators of amniotic fluid embolism of the present invention. The real-time monitoring system for serological indicators of amniotic fluid embolism includes a sampling device 1, a 405nm excitation light source array 2, a microfluidic chip detection platform 3, a 580nm filter layer 4, a double-gate photoelectric thin film transistor array 5, and a signal processing circuit (not shown in the figure). Show). The sampling device 1 is connected to the microfluidic chip detection platform 3, the 405nm excitation light source array 2, the microfluidic chip detection platform 3, the 580nm filter layer 4 and the double-gate photoelectric thin film transistor array 5 are arranged sequentially from top to bottom, and the signal processing The circuit is used for processing the current change signal between the drains of the double gate photoelectric thin film transistor arr...

Embodiment 2

[0031] see figure 1 The real-time monitoring system for serological indicators of amniotic fluid embolism includes a sampling device 1, a 405nm excitation light source array 2, a microfluidic chip detection platform 3, a 580nm filter layer 4, a double-gate photoelectric thin film transistor array 5, and a signal processing circuit (not shown). icon). The sampling device 1 is connected to the microfluidic chip detection platform 3, the 405nm excitation light source array 2, the microfluidic chip detection platform 3, the 580nm filter layer 4 and the double-gate photoelectric thin film transistor array 5 are arranged sequentially from top to bottom, and the signal processing The circuit is used for processing the current change signal between the drains of the double gate photoelectric thin film transistor array.

[0032] like Figure 4 , the microfluidic chip detection platform 3 includes a blood sampling channel 31', a plasma area 32', an antibody immobilization area 33', an...

Embodiment 3

[0034] see figure 1 , image 3 , the real-time monitoring method of serological index of amniotic fluid embolism of the present invention, comprises the following several steps: (1) takes trace blood from puerpera body by sampling device 1, injects microfluidic chip detection platform 3, ZnCp-I is extracted from blood (2) above the microfluidic chip detection platform 3, a 405nm excitation light source array is used to irradiate the ZnCp-I separated by the microfluidic chip detection platform 3 to make it generate fluorescence; (3) the above fluorescence is transmitted through The 580nm filter layer 4 below the microfluidic chip detection platform 3; (4) only the part of the fluorescence with a wavelength of 580nm passes through, and irradiates into the double-gate photoelectric thin film transistor below the 580nm filter layer 4 On the array 5; (5) The signal processing circuit processes the current change signal between the drains of the double-gate photoelectric thin film ...

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Abstract

The invention discloses a real-time monitoring system for amniotic fluid embolism serological indicators. The system comprises a sampling device, a 405nm excitation light source array, a micro-fluidic chip detection platform, a 580nm filter layer, a double-gate photoelectric film transistor array and a signal processing circuit. The invention further discloses a monitoring method adopting the real-time monitoring system for the amniotic fluid embolism serological indicators. When a ZnCp-I value in blood exceeds a safe threshold value or is excessively increased, alarm signals are transmitted, so that medical staff can pay attention to conditions and perform emergency treatment, time is saved for lying-in women and the medical staff, and rescue success rate is increased. Compared with the prior art, the real-time monitoring system has the advantages that the system is low in sampling quantity, short in consumed time and high in integration when single measurement is performed, and multiple measurement can be achieved.

Description

technical field [0001] The invention relates to a real-time monitoring system and monitoring method for serological indexes of amniotic fluid embolism. Background technique [0002] Amniotic fluid embolism is a rare but extremely dangerous obstetrical disease. Its onset is sudden, the condition develops rapidly, and the symptoms are dangerous. Within minutes of onset, the patient may be dying. Therefore, it is the key to rescue patients with amniotic fluid embolism to pay close attention to the relevant vital signs during the delivery process, and to carry out emergency treatment in time when signs of amniotic fluid embolism are found. However, at present, medical staff can only rescue amniotic fluid embolism when they observe symptoms related to amniotic fluid embolism, which undoubtedly shortens the time for medical staff to treat symptoms and increases the difficulty of rescue. [0003] If some indicators related to amniotic fluid embolism can be detected in the maternal...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N33/577
CPCG01N33/54366G01N2800/36
Inventor 王凯何汉涛陈艺文
Owner 广东省安家医健健康管理有限公司
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