Thin film surface uniform shearing force loading device

Abstract

The invention provides a thin film surface uniform shearing force loading device, relates to the field of biomechanical researches and belongs to the field of a thin film surface mechanical loading experiment device. The thin film surface uniform shearing force loading device is composed of a bottom plate, a glass slide, a thin film, a silica gel gasket, a sealing ring, a cover plate and a 316L stainless steel connector; the bottom plate and the cover plate are made of a polycarbonate material with relatively good biocompatibility. A groove type design is adopted so that an inlet / outlet buffering groove is formed in a drainage basin and an inlet / outlet is vertical to a groove surface, so that fluid pressure generated by flowing does not directly act on an L-shaped necking hole; an L-shaped necking hole structure is additionally arranged at one end, close to an effective action flat plate region, of the groove to form a phase-change inlet / outlet structure which is relatively effective and stable, so that fluid relatively stably flows in the effective action flat plate region, an effective action region range is definite and an effective action area ratio is improved. Figure 1 is a schematic diagram of a mechanical assembling structure.

Description

technical field [0001] The invention relates to a film surface uniform shear force loading device. Background technique [0002] With the development of polymer degradable material preparation technology, more and more polymer materials have been widely used in the field of biomedical engineering, such as PLA, PLGA and so on. Since many polymer degradable materials are broken through lipid bonds in aqueous solution, and finally hydrolyzed into water and carbon dioxide, they are non-toxic and harmless to the human body, and have good biocompatibility and degradability. Some polymer degradable materials have been It is used in drug coating sustained release or drug-loaded particles, etc., and has good promotion value, especially in the aspect of drug sustained release coating on the surface of vascular metal stents. However, due to the complex degradation process of polymer degradable materials, which is closely related to the solution composition, temperature, pH value, mech...

AI Technical Summary

Problems solved by technology

However, due to the complex degradation process of polymer degradable materials, which is closely related to the solution composition, temperature, pH value, mechanical environment and other factors, it has not been fully grasped so far.

At the same time, since the thickness of the polymer degradable coating is generally relatively thin, it is not conducive to the direct loading of force.

Images