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Enteral nutrient for oncotherapy and preparation method thereof

A nutrient and vitamin technology, applied in the field of medicine, can solve the problems of few types of enteral nutrition preparations, no enteral nutrition preparations, etc.

Inactive Publication Date: 2017-05-17
北京康爱医疗科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, there are many kinds of enteral nutrition preparations such as "Ansu", "Nengquansu", "Nengquanquan" and "Baipusu" on the market, but they are generally suitable for patients with malnutrition or intake disorders. There are few types of enteral nutrition preparations for cancer patients during the peri-treatment period, especially for patients with malignant tumors and diabetes, there are no enteral nutrition preparations

Method used

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  • Enteral nutrient for oncotherapy and preparation method thereof
  • Enteral nutrient for oncotherapy and preparation method thereof
  • Enteral nutrient for oncotherapy and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] Embodiment 1: the preparation of nutritional agent of the present invention

[0060] 1. The raw materials are as shown in Table 1:

[0061] Table 1: The preparation raw material of nutritional agent of the present invention

[0062]

[0063]

[0064]

[0065] 2. Preparation method:

[0066] (1) Prepare the following solutions:

[0067] Solution A: Composed of medium-chain triglycerides, soybean oil, canola oil, linseed oil, emulsifiers (lecithin, fatty acid glycerides, glyceryl succinate) and fat-soluble vitamin premixes (vitamin A, vitamin D, vitamin E, vitamin K) composition;

[0068] Solution B: composed of casein, whey protein, soy protein and water;

[0069] Solution C: composed of water, fructose, indigestible maltodextrin, maltodextrin, fructooligosaccharides, inulin, isomaltulose and potassium hydroxide with a concentration of 40% by weight;

[0070] Solution D: composed of non-fat-soluble vitamins (vitamin C, choline chloride, niacin, vitamin B ...

Embodiment 2

[0095] Embodiment 2: the preparation of nutritional agent of the present invention

[0096] 1. The raw materials are as shown in Table 4:

[0097] Table 4: The preparation raw material of nutritional agent of the present invention

[0098]

[0099]

[0100]

[0101] 2. Preparation method:

[0102] (1) Prepare the following solutions:

[0103] Solution A: Composed of medium-chain triglycerides, soybean oil, canola oil, linseed oil, emulsifiers (lecithin, fatty acid glycerides, glyceryl succinate) and fat-soluble vitamin premixes (vitamin A, vitamin D, vitamin E, vitamin K) composition;

[0104] Solution B: composed of casein, whey protein, soy protein and water;

[0105] Solution C: composed of water, fructose, indigestible maltodextrin, maltodextrin, fructooligosaccharides, inulin, isomaltulose and potassium hydroxide with a concentration of 40% by weight;

[0106] Solution D: composed of non-fat-soluble vitamins (vitamin C, choline chloride, niacin, vitamin B ...

Embodiment 3

[0128] Example 3: The clinical application and tolerance of the nutritional agent of the present invention in radiotherapy for patients with esophageal cancer

[0129] Radiotherapy is one of the main treatment methods for patients with advanced esophageal cancer, and radiotherapy often leads to severe mucositis, painful swallowing and aggravated dysphagia, resulting in insufficient energy and protein intake. Malnutrition will affect the treatment effect of malignant tumor patients, reduce the quality of life, shorten the survival time, and increase medical expenses. Formula food for special medical purposes is a formula food that is specially processed and formulated to meet the special needs of nutrients or diet for people with restricted eating, digestive and absorption disorders, metabolic disorders or specific disease states, and plays an important role in nutritional support. The nutritional agent of the present invention is a high-energy, high-protein, high-fat, low-ca...

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Abstract

The invention provides an enteral nutrient for oncotherapy. 1000mL of the enteral nutrient for oncotherapy comprises 70-95g of proteins, 54-74g of fat, 77-115g of carbohydrates, 20-50g of dietary fibers, 171-319g of taurine, 100-156mg of carnitine, 300-419mg of yeast extract, 0.5-2g of vitamins, 4-9g of inorganic salts and 650-710g of water. The enteral nutrient with high content of proteins, high content of fat and low content of carbohydrates meets the metabolic characteristics of tumor patients, can selectively hunger tumor cells but not affect normal cell functions, so that the enteral nutrient is in particular suitable for the tumor patients with diabetes and effectively reverses malnutrition, and the living quality of the tumor patients is improved.

Description

[0001] This application claims all the rights and interests of the priority of the Chinese patent application with the application number 201510753312.4 and titled "An enteral nutrition agent for tumor treatment and its preparation method" filed on November 6, 2015. The Chinese patent The entire content of the application is incorporated herein by reference. technical field [0002] The invention belongs to the technical field of medicine, and in particular relates to an enteral nutrition agent for tumor treatment and a preparation method thereof. Background technique [0003] Studies have found that 40-80% of cancer patients will suffer from malnutrition. Metabolic abnormalities of malignant tumors and related treatment measures will lead to or aggravate malnutrition, which will significantly increase the mortality and medical expenses of malignant tumors, resulting in a significant decrease in the treatment effect, quality of life and survival time of patients with maligna...

Claims

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Application Information

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IPC IPC(8): A61K38/17A23L33/10A23L33/115A23L33/125A23L33/15A23L33/155A23L33/16A23L33/175A23L33/185A23L33/19A23L33/21A23L33/145A61P35/00A61P3/02A61P3/10A61K38/16A61K36/55A61K31/718A61K31/7004A61K31/7032A61K31/702A61K31/733A61K31/185A61K31/205A61K31/375A61K31/355A61K31/07A61K31/14A61K31/455A61K31/714A61K31/197A61K31/51A61K31/59A61K31/4415A61K31/525A61K31/122A61K31/519A61K31/4188A61K33/10A61K31/194A61K33/06A61K33/14A61K33/42A61K33/30A61K33/26A61K33/32A61K33/34A61K33/24A61K33/04A61K33/18
CPCA23V2002/00A61K31/07A61K31/122A61K31/14A61K31/185A61K31/194A61K31/197A61K31/205A61K31/355A61K31/375A61K31/4188A61K31/4415A61K31/455A61K31/51A61K31/519A61K31/525A61K31/59A61K31/7004A61K31/702A61K31/7032A61K31/714A61K31/718A61K31/733A61K33/04A61K33/06A61K33/10A61K33/14A61K33/18A61K33/24A61K33/26A61K33/30A61K33/32A61K33/34A61K33/42A61K36/064A61K36/31A61K36/48A61K36/55A61K38/16A61K38/168A61K38/1709A61K2300/00A23V2200/30A23V2200/308A23V2250/0612A23V2250/0644A23V2250/156A23V2250/1944A23V2250/218A23V2250/5062A23V2250/5114A23V2250/54246A23V2250/54252A23V2250/5488A23V2250/606A23V2250/62A23V2250/70
Inventor 石汉平应希堂丛明华方玉韩梅栾春娜商维虎
Owner 北京康爱医疗科技股份有限公司
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