Preservative containing capryloyl hydroximic acid and p-hydroxy phenyl ethyl ketone and preparation method and application of preservative and cosmetic containing preservative

A technology containing p-hydroxyacetophenone and caprylyl hydroxamic acid, which is applied in the field of cosmetics containing this preservative, can solve the problems of high irritation, high toxicity, and unsatisfactory safety, and prevent spoilage , Mild in nature, the effect of using the quality will not be reduced

Inactive Publication Date: 2017-05-31
福州美乐莲生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the preservatives added to most cosmetics have the defec...

Method used

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  • Preservative containing capryloyl hydroximic acid and p-hydroxy phenyl ethyl ketone and preparation method and application of preservative and cosmetic containing preservative
  • Preservative containing capryloyl hydroximic acid and p-hydroxy phenyl ethyl ketone and preparation method and application of preservative and cosmetic containing preservative
  • Preservative containing capryloyl hydroximic acid and p-hydroxy phenyl ethyl ketone and preparation method and application of preservative and cosmetic containing preservative

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] According to weight percentage, prepare 5% caprylyl hydroxamic acid, 40% p-hydroxyacetophenone, 45% 1,2-propanediol and 10% PEG-40 hydrogenated castor oil.

[0028] Put caprylyl hydroxamic acid, p-hydroxyacetophenone and 1,2-propanediol at 45°C and stir, then add PEG-40 hydrogenated castor oil, and stir at 75°C to prepare caprylyl hydroxamic acid and para-hydroxyacetophenone as a preservative, which has a pH of 3.0.

[0029] The preservative containing octanoyl hydroxamic acid and p-hydroxyacetophenone can be added to cream cosmetics at 1 wt%, and the pH of the cream cosmetics is 3.0.

Embodiment 2

[0031] According to weight percentage, prepare 30% caprylyl hydroxamic acid, 10% p-hydroxyacetophenone, 57% 1,3-butanediol and 3% PEG-40 hydrogenated castor oil.

[0032] Put caprylyl hydroxamic acid, p-hydroxyacetophenone and 1,3-butanediol at 75°C and stir, then add PEG-40 hydrogenated castor oil, and stir at 45°C to obtain caprylyl hydroxamic acid Preservative for oxamic acid and p-hydroxyacetophenone, its pH is 3.6.

[0033] 0.5 wt% of the preservative containing caprylyl hydroxamic acid and p-hydroxyacetophenone can be added to the mask liquid, and the pH of the mask liquid is 3.6.

Embodiment 3

[0035] Prepare 15% caprylyl hydroxamic acid, 25% p-hydroxyacetophenone, 35% 1,3-propanediol, 10% 1,2-pentanediol and 10% 1,2- Hexylene glycol, 2.5% PEG-40 hydrogenated castor oil and 2.5% C 12-13 alketh-9.

[0036] Caprylyl hydroxamic acid, p-hydroxyacetophenone, 1,3-propanediol, 1,2-pentanediol and 1,2-hexanediol were stirred at 55°C, and then PEG-40 hydrogenated castor oil and C 12-13 Alketh-9 was stirred at 55°C to prepare a preservative containing caprylyl hydroxamic acid and p-hydroxyacetophenone, the pH of which was 4.0.

[0037] The preservative containing octanoyl hydroxamic acid and p-hydroxyacetophenone can be added in 1.5wt% to cream cosmetics, and the pH of the cream cosmetics is 4.0.

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Abstract

The invention relates to a preservative containing capryloyl hydroximic acid and p-hydroxy phenyl ethyl ketone and a preparation method and application of the preservative and a cosmetic containing the preservative, and belongs to the field of preservatives. The preservative containing the capryloyl hydroximic acid and the p-hydroxy phenyl ethyl ketone is prepared by stirring the raw materials in percentage by weight: 5-30% of capryloyl hydroximic acid, 10-40% of p-hydroxy phenyl ethyl ketone, 30-60% of C3-C8 dihydric alcohol at 45-75 DEG C and adding 3-10% of a solubilizer for stirring at 45-75 DEG C. The preservative can be added to the cosmetic for application, and the adding amount is 0.5-5.0wt%. The preservative containing the capryloyl hydroximic acid and the p-hydroxy phenyl ethyl ketone has efficient broad-spectrum sterilization capability, does not release harmful substances of formaldehyde and the like, has good bactericidal and bacteriostatic preservative effects when applied to the cosmetic, and also has the effects of being mild and free of thrill to skin.

Description

technical field [0001] The invention relates to the field of preservatives, and in particular to a preservative containing octanoylhydroxamic acid and p-hydroxyacetophenone, a preparation method and application thereof, and cosmetics containing the preservative. Background technique [0002] The use of cosmetics has a very long history. In the past 30 years, the cosmetics industry in various countries in the world has developed rapidly, and the use of cosmetics by humans has become more and more common. Cosmetics have developed from luxury goods to daily necessities for human fragrance and beauty. Cosmetics are used all over the skin, hair, nails, lips and teeth on the surface of the human body, and the safety of use should be taken seriously. Most cosmetics are rich in the nutrients needed for the growth of microorganisms. Once the microorganisms in the environment enter, they can multiply rapidly, destroying the sensory quality of the product and harming the health of cons...

Claims

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Application Information

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IPC IPC(8): A61K8/40A61K8/35A61K8/34A61K8/37A61Q19/00
CPCA61K8/40A61K8/34A61K8/345A61K8/35A61K8/37A61K2800/10A61K2800/48A61K2800/524A61Q19/00
Inventor 肖永堂成佳佳
Owner 福州美乐莲生物科技有限公司
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