Liquid control valve apparatus used for micro-fluidic chip and micro-fluidic chip thereof

Abstract

The invention discloses a liquid control valve apparatus used for a micro-fluidic chip and the micro-fluidic chip thereof. The valve apparatus comprises a detection mechanism used for sensing whether the liquid flows through an installation position of the valve apparatus; the feedback value from the detection mechanism shows that the liquid flows through the installation position of the valve apparatus, the valve apparatus in a normally-opened state in the micro-fluidic chip is capable of automatically closing and is in a cut-off state; the valve apparatus in the cutoff state is capable of timely opening and is in a circulation state; the fluid can be circulated in valve apparatus which is in the circulation state under promotion of air flow provided by air passage. The valve apparatus can switch the valve at any time, and can guarantee requirement of large scale production.

Description

technical field [0001] The invention relates to a valve device, in particular to a liquid control valve device for a microfluidic chip. [0002] The invention also relates to a microfluidic chip. Background technique [0003] Immunolateral flow-through diagnostic technology is a stable and practical technology suitable for use in various point-of-care tests (POCT) or on-site. [0004] In the immune system response system, the CV is large due to system reasons, and accurate quantification cannot be achieved. The immunodiagnostic method based on microfluidic technology can effectively avoid the above problems. [0005] There are two types of microfluidics: passive and active. Passive microfluidics still requires capillary force to achieve liquid-forward lateral flow. However, due to the different viscosities of different samples, especially whole blood samples, the liquid flow rate cannot be uniform. [0006] Active microfluidics can effectively avoid the above problems, ...

AI Technical Summary

Problems solved by technology

[0010] The existing microfluidic chip valve device has a single function and low stability, and can only prevent the liquid from moving when it is closed.

[0011] Some valves have too high requirements for the combination precision of the upper and lower microfluidic chips, and cannot achieve mass production. A slight change in size will cause the liquid valve to fail, which cannot prevent the flow of liquid.

[0012] Or some valves are used once and cannot be operated repeatedly. For complex microfluidic operations, disposable valves will lead to complicated microfluidic flow channel design and larger volume

Cannot achieve the delicate and stable purpose of POCT

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