Traditional Chinese medicine composition for treating osteoporosis

A technology of osteoporosis and composition, which is applied in the direction of drug combination, medical raw materials derived from molluscs, bone diseases, etc., can solve the problems of increasing the incidence of venous thromboembolism, achieve the enhancement of the original drug effect, and restore the youthful state of bone marrow , Improve the effect of pathological conditions

Inactive Publication Date: 2017-07-11
LIAONING UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Long-term use of calcium supplements can cause side effects such as indigestion, constipation, and myocardial infarction. Long-term use of estrogen and progesterone can increase the incidence of breast cancer, coronary heart disease, stroke, and venous thromboembolism; selective estrogen receptor modulators , such as raloxifene, lasofoxifene, bazedoxifene, etc., increase the risk of venous thromboembolism by 3 times, etc.

Method used

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  • Traditional Chinese medicine composition for treating osteoporosis
  • Traditional Chinese medicine composition for treating osteoporosis
  • Traditional Chinese medicine composition for treating osteoporosis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] A traditional Chinese medicine formula for osteoporosis, which is composed of the following raw materials in parts by weight: 15 parts of red deer bone, 10 parts of rhizoma drynaria, 10 parts of Eucommia ulmoides, 5 parts of ginseng, 5 parts of astragalus, 5 parts of rehmannia glutinosa, and sealwort 5 parts, 5 parts of medlar, 5 parts of epimedium, 5 parts of psoralen, 5 parts of Panax notoginseng, 5 parts of calcined oyster.

[0040] The preparation method of the traditional Chinese medicine composition for treating osteoporosis comprises the following steps.

[0041] Step 1. Pretreatment: Receive the materials according to the production instructions and check the material code, product name, specification, serial number and weight, etc., and remove the coat and disinfect.

[0042] Step 2. Granulation: take red deer bone, rhizoma drynariae, Eucommia ulmoides, ginseng, astragalus, rehmannia glutinosa, sealwort, medlar, epimedium, psoralen, notoginseng, calcined oyster...

Embodiment 2

[0050] A traditional Chinese medicine formula for osteoporosis, which is composed of the following raw materials in parts by weight: 5 parts of red deer bone, 15 parts of drynaria fortunei, 15 parts of Eucommia ulmoides, 10 parts of ginseng, 10 parts of astragalus, 10 parts of rehmannia glutinosa, sealwort 10 parts, 10 parts of medlar, 10 parts of epimedium, 10 parts of psoralen, 10 parts of Panax notoginseng, 5 parts of calcined oyster.

Embodiment 3

[0052] A traditional Chinese medicine formula for osteoporosis, which is composed of the following raw materials in parts by weight: 10 parts of red deer bone, 5 parts of Rhizoma drynariae, 5 parts of Eucommia ulmoides, 15 parts of ginseng, 15 parts of astragalus, 15 parts of rehmannia glutinosa, and 15 parts of sealwort 15 parts of medlar, 15 parts of epimedium, 15 parts of psoralen, 15 parts of Panax notoginseng, 10 parts of calcined oyster.

[0053] 1. Experimental data.

[0054] 60 healthy female Wistar rats were selected and randomly divided into 5 groups, wherein: Group A was the sham operation group (SHAM), 10 rats; Group B was the ovariectomy group (OVX), 10 rats; Group C was the ovariectomy group, 10 (ovariectomy+Gushukang granules); D1 group is the low-dose group of traditional Chinese medicine combination of osteoporosis of embodiment 1, 10 (ovariectomy+low dose); D2 group is the osteoporosis of embodiment 1 Chinese medicine combination medium dose group, 10 (ovari...

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Abstract

The invention belongs to the technical field of traditional Chinese medicines and relates to a traditional Chinese medicine composition for treating osteoporosis. The traditional Chinese medicine composition is composed of 5 to 15 portions by weight of red deer bone, 5 to 15 portions by weight of drynaria rhizome, 5 to 15 portions by weight of bark of eucommia, 5 to 15 portions by weight of ginseng, 5 to 15 portions by weight of radix astragali, 5 to 15 portions by weight of prepared rehmannia root, 5 to 15 portions by weight of rhizoma polygonati, 5 to 15 portions by weight of Chinese wolfberry, 5 to 15 portions by weight of epimedium, 5 to 15 portions by weight of fructus psoraleae, 5 to 15 portions by weight of pseudo-ginseng and 5 to 15 portions by weight of calcined oyster. The composition realizes a low raw material cost, is easy to use, is practical, can effectively treat osteoporosis and has small side effects.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating osteoporosis. Background technique [0002] Osteoporosis refers to a systemic disease in which the bone mass per unit volume of bone decreases and the microstructure of bone tissue is destroyed, resulting in increased bone fragility and prone to fractures. With the prolongation of people's life expectancy and the aging of society, its incidence is gradually increasing. Complications such as fractures caused by osteoporosis can cause disability and death, and bring a heavy burden to patients, families and society. It is called a "silent epidemic". According to statistics, people who are susceptible to osteoporosis include postmenopausal women, men over 60 years old, hypogonadism, long-term nutritional deficiencies, less exercise and underweight, and are closely related to personal living habits such as ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P19/10A61K35/32A61K35/618
Inventor 张立德乔铁鞠宝兆郑冰元梁可李芳潇朱明丹马进
Owner LIAONING UNIV OF TRADITIONAL CHINESE MEDICINE
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