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Artificial soft tissue braided fabric, preparation method and application thereof

A braided and soft tissue technology, applied in the field of medical and surgical repair materials, can solve the problems of inability of cells in the middle dense part to grow in, unable to meet mechanical requirements, etc., achieve good biocompatibility, promote adhesion growth, and enhance growth and proliferation. Effect

Active Publication Date: 2017-07-18
SUZHOU MINIMALLY INVASIVE SPINAL TRAUMA MEDICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The use of silk protein as the matrix of artificial ligaments has become the main direction of the existing artificial ligament research. In 2007, the silk tendon developed by Tianjin Medical University had the problem that the cells in the middle densities could not grow into it due to structural limitations; Singapore Hongbing Fan silk ligament and 2013 The multi-strand silk artificial ligament invented by Suzhou Ruishi Medical Technology Co., Ltd. cannot meet the mechanical requirements of clinical reconstruction

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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  • Artificial soft tissue braided fabric, preparation method and application thereof
  • Artificial soft tissue braided fabric, preparation method and application thereof
  • Artificial soft tissue braided fabric, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] Fabrication of ultra-high-strength and low-model artificial soft tissue braids

[0060] Weaving method (see attached figure 2 ):

[0061] Organization process:

[0062] Front comb GB1: 1-0 / 0-1 / / full wear

[0063] Back comb GB2:2-3 / 3-2 / 1-0 / 2-3 / 1-0 / 0-1 / 2-3 / 1-0 / / full wear

[0064] Full weft insertion: 2 threads, 1 empty, 1 thread, 1 empty, 2 threads, 1 empty.

[0065] Weft direction: Lining yarn (PET: PEHM=0:1), that is, weft insertion yarn is only composed of PEHM; Silk, the surface is basically covered by silk, and the inner layer is a sandwich structure of synthetic fiber silk.

[0066] In this embodiment, the sandwich structure is that the upper surface layer 100 is composed of silk, the middle layer 200 is composed of PET, the inner layer 300 is composed of PEHM, the middle layer 400 is composed of PET, and the lower surface layer 500 is composed of silk. The middle layer 200, the inner layer 300 and the middle layer 400 composed of synthetic fiber silk are use...

Embodiment 2

[0068] Fabrication of high-strength low-model artificial soft tissue braids

[0069] Weaving method (see attached image 3 )

[0070] Organization process:

[0071] Front comb GB1: 1-0 / 0-1 / / full wear

[0072] Back comb GB2:2-3 / 3-2 / 1-0 / 2-3 / 1-0 / 0-1 / 2-3 / 1-0 / / full wear

[0073] Full weft insertion: 2 threads, 1 empty, 1 thread, 1 empty, 2 threads, 1 empty.

[0074] Weft direction: cushion yarn (PET: PEHM=1:1); warp direction: front comb silk weave for chain weave, back comb PET weave for changing warp and satin weave; front comb is made of silk, the surface is basically covered by silk , the inner layer is a sandwich structure of synthetic fiber silk.

[0075] In this embodiment, the sandwich structure is that the upper surface layer 100 is made of silk, the middle layer 200 is made of PET, and the inner layer 300 is made of PEHM or PET (that is, in the sections of different positions, the inner layer 300 may be PEHM or PET), the middle layer 400 is composed of PET, and the ...

Embodiment 3

[0077] Preparation of high-strength, low-modulus and large-porosity artificial soft tissue braids

[0078] Weaving method (see attached Figure 4 ):

[0079] Organization process:

[0080] Front comb GB1: 1-0 / 0-1 / / full wear

[0081] Back comb GB2:2-3 / 3-2 / 1-0 / 2-3 / 1-0 / 0-1 / 2-3 / 1-0 / / full wear

[0082] Full weft insertion: 2 threads, 1 empty, 1 thread, 1 empty, 2 threads, 1 empty.

[0083] Weft direction: Lining yarn (PET: PEHM: SILK=2:2:1), Warp direction: Front bar silk and chemical fiber (PET, PEHM) are alternately woven to make chain weave, back comb uses PET: PEHM: SILK = 1:1:1 weaving, changing warp and satin weave. Through reasonable yarn threading, one chemical fiber loop and one SILK loop are realized in the warp direction. Due to the degradation of silk fibers, the fabric becomes more porous. The fabric of this design has the characteristics of high strength, low modulus, and low creep.

[0084] In this embodiment, the upper surface layer 100 of the sandwich struc...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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PUM

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Abstract

The invention aims to provide an artificial soft tissue braided fabric which has excellent mechanical properties, such as dynamic properties and facilitates cell growth and a preparation method for the braided fabric. The artificial soft tissue braided fabric disclosed by the invention comprises a first surface layer, a first middle layer, an inner layer, a second middle layer and a second surface layer in turn; the first surface layer and the second surface layer are locally or wholly prepared from silks; the first middle layer and the second middle layer are locally or wholly prepared from PET; and the inner layer is locally or wholly prepared from PEHM.

Description

technical field [0001] The invention relates to medical surgical repair materials, in particular to an artificial soft tissue braid and its preparation method and application. Background technique [0002] The difficulty and focus of the clinical application of artificial ligaments is the use of biomaterials to intervene in the treatment of tendon-ligament adhesions. After tendon injury, the integrity of the tendon sheath is destroyed, the balance of the synovial fluid system is broken, and the blood supply is reduced. The repair of the injury mainly relies on the growth of connective tissue around the tendon to heal, while the growth and repair of the tendon tissue itself is limited, resulting in its healing. The cycle is longer and it is even difficult to achieve the effect of rehabilitation. In addition, it is easy to cause the formation of a large amount of scar tissue during the healing process, so it is easier to form adhesions and affect the effect of rehabilitation. ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/36A61L27/16A61L27/18A61L27/56A61F2/08D04B21/14D04B21/16
CPCA61L27/16A61L27/18A61L27/3604A61L27/3662A61L27/56A61F2/08D04B21/14D04B21/165A61L2430/10C08L23/06C08L67/02
Inventor 张凤羽耿芳季向茹
Owner SUZHOU MINIMALLY INVASIVE SPINAL TRAUMA MEDICAL TECH CO LTD
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