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A developing composition and its preparation method and application

A developing composition and developing agent technology, which is applied in X-ray contrast agent preparation, pharmaceutical formula, dental preparation, etc., can solve the problems of inability to measure the thickness objectively and accurately, easily compress the gums, affect the measurement accuracy, etc., and achieve easy repositioning , exact developing effect and high measurement accuracy

Active Publication Date: 2019-12-06
惠州市口腔医院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Disadvantages: the thickness cannot be measured objectively and accurately
Disadvantages: This method is complicated to make, and the alginate impression material with radioactive barium sulfate in the prepared silicone rubber personality tray is easy to compress the gingiva when it is repositioned, until the gingiva shifts, affecting the measurement accuracy
Disadvantages: Personalized trays also have difficulties in re-sealing accuracy, and may compress the gums, affecting measurement accuracy

Method used

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  • A developing composition and its preparation method and application
  • A developing composition and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] An indirect contrast agent for measuring gum thickness, comprising the following components in parts by weight: 100 parts of iopamidol injection and 20 parts of agar.

[0023] The preparation method of this indirect developer comprises the following steps:

[0024] (a) Heat the agar at room temperature to 98°C for 7 minutes until it becomes a sol, dissolve the agar under heating conditions and mix in water-soluble iopamidol injection, and mix evenly to obtain a mixture. The specification of iopamidol injection used is 37 g (I) / 100 ml / bottle;

[0025] (b) The temperature of the mixture is cooled to a gel state to obtain a developing composition.

Embodiment 2

[0027] An indirect contrast agent for measuring gum thickness, comprising the following components in parts by weight: 150 parts of iopamidol injection and 20 parts of agar.

[0028] The preparation method of this indirect developer comprises the following steps:

[0029] (a) Heat the agar at room temperature to 95°C for 9 minutes until it becomes a sol, dissolve the agar under heating conditions and mix in water-soluble iopamidol injection, and mix evenly to obtain a mixture. The specification of iopamidol injection used is 37 g (I) / 100 ml / bottle;

[0030] (b) The temperature of the mixture is cooled to a gel state to obtain a developing composition.

Embodiment 3

[0032] An indirect contrast agent for measuring gum thickness, comprising the following components in parts by weight: 100 parts of iopamidol injection and 10 parts of agar.

[0033] The preparation method of this indirect developer comprises the following steps:

[0034] (a) Heat the agar at room temperature to 99°C and keep it for 5 minutes until it turns into a sol, dissolve the agar under heating conditions and mix it with water-soluble iopamidol injection, and mix evenly to obtain a mixture. The specification of iopamidol injection used is 37 g (I) / 100 ml / bottle;

[0035] (b) The temperature of the mixture is cooled to a gel state to obtain a developing composition.

[0036] The gingival thickness measurement clinical application of embodiment 1,2,3 is illustrated in conjunction with accompanying drawing:

[0037] The reference numerals are: tooth development 1, tooth outer surface 11, alveolar bone 2, alveolar bone outer surface 21, indirect developer development 3, in...

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Abstract

The invention discloses a developing composition, which comprises the following components in parts by weight: 10-25 parts of an excipient, and 100-150 parts of a nonionic water soluble contrast medium. The invention also discloses a preparation method of the developing composition, and application of the developing composition as an indirect developer for measuring gingivae thickness. The developer disclosed by the invention can be used for cone beam computed tomography (CBCT) to clearly and accurately develop the interface between the gingival lateral surface and the developer with accurate measurement, and achieves a good effect in clinics.

Description

technical field [0001] The invention relates to the field of dentistry, in particular to a developing composition for measuring gum thickness, as well as its preparation method and application. Background technique [0002] Gingival thickness is a major criterion for determining gingival biotype. Thin gingiva is prone to gingival recession, which affects the aesthetic effect of implants and conventional crown restorations. Thin gingival type is much more risky for aesthetic restoration than posterior gingival type. Therefore, it is necessary to make an objective and accurate judgment on the thickness of the gingiva before clinical operation, so as to adopt an appropriate plan (such as soft tissue transplantation, etc.) to improve it. [0003] At present, there is no uniform method for measuring gingival thickness clinically. There are three existing methods for measuring gingival thickness: 1. In gingival type, a periodontal probe is often inserted 1 mm below the gum in cl...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K49/04A61K6/00
CPCA61K6/25A61K49/0438
Inventor 邹新明
Owner 惠州市口腔医院有限公司
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