Preparation method for curcumin-loaded nano-emulsion

A technology for carrying curcumin and nanoemulsion is applied in the field of preparation of carrying curcumin nanoemulsion, which can solve the problems of hidden safety hazards and high cost, and achieve the effects of reducing preparation cost, low production cost and good emulsifying performance.
CN107028883AActive Publication Date: 2017-08-11NORTHEAST AGRICULTURAL UNIVERSITY
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
NORTHEAST AGRICULTURAL UNIVERSITY
Publication Date
2017-08-11

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Abstract

The invention provides a preparation method for a curcumin-loaded nano-emulsion, belonging to the technical field of curcumin nano-emulsions. The preparation method provided by the invention overcomes the technical problems of potential safety hazards and high cost of conventional preparation methods for curcumin-loaded nano-emulsions. The preparation method comprises the following steps: 1, subjecting beta-conglycinin to ultrasonic treatment, enzymatic hydrolysis or glycosylation so as to prepare a water phase; and 2, mixing the water phase with an oil phase which is prepared from curcumin and middle-chain triglyceride, carrying out homogenization, and then carrying out treatment in an ultrasonic cell disruptor so as to obtain the curcumin-loaded nano-emulsion. The curcumin-loaded nano-emulsion prepared by using the method in the invention has a high entrapment rate. The method provided by the invention reduces preparation cost and can guarantee that the prepared curcumin-loaded nano-emulsion is healthy, safe and excellent in quality; and the method is more suitable for industrial production.
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Description

technical field

[0001] The invention belongs to the technical field of curcumin nanoemulsion, and specifically relates to a preparation method for carrying curcumin nanoemulsion. Background technique

[0002] Curcumin is an acidic polyphenolic compound extracted from the rhizomes of turmeric plants such as turmeric, zedoary, calamus, turmeric, etc. and other pharmacological activities.

[0003] However, curcumin is a lipophilic substance with poor water solubility, and its bioavailability is low when it is taken into the body in the form of solid particles, suspensions, etc., and it is difficult to achieve the desired health care effect.

[0004] There are still deficiencies in the existing disclosed methods for preparing nanoemulsions carrying curcumin. For example, the preparation of nanoemulsions by low-energy emulsification requires the use of a large amount of emulsifiers. After the nanoemulsion of curcumin is put into production and commercialized, there are potentia...

Claims

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