Unlock instant, AI-driven research and patent intelligence for your innovation.

Method of separating purification saponin glycosides composition from achyranthes longifolia makino

A technology of separation and purification, saponins, applied in the field of natural medicinal chemistry, can solve the problems of few research reports on the components of Achyranthes chinensis

Inactive Publication Date: 2017-08-11
SOUTHWEST UNIVERSITY FOR NATIONALITIES
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Achyranthes bidentata is a commonly used clinical medicinal material in Yi medicine in Liangshan Yi Autonomous Prefecture of Sichuan, Chuxiong Yi Autonomous Prefecture of Yunnan, and Guichuan. Currently, there are few research reports on the components of Achyranthes bidentata

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method of separating purification saponin glycosides composition from achyranthes longifolia makino
  • Method of separating purification saponin glycosides composition from achyranthes longifolia makino
  • Method of separating purification saponin glycosides composition from achyranthes longifolia makino

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] In order to further clarify the chemical components and active ingredients in the Yi medicine Achyranthes bidentata, obtain reference substances, establish the quality standards of the medicinal material Achyranthes bidentata and its prescription preparations, and clarify the material basis of the pharmacological effects of Achyranthes bidentata, this example studies the medicinal materials of Achyranthes bidentata. The chemical composition has been studied systematically.

[0041] 1 Instruments and materials

[0042] 1.1 Instrument

[0043] Waters Acquity UPLC H-Class System ultra-high performance liquid chromatography (Waters, USA); METTLER AE240 electronic analytical balance (Mettler-Toledo (Shanghai) Instrument Co., Ltd.); KQ-250B ultrasonic cleaner (Kunshan City) Ultrasonic Instrument Co., Ltd.); IKA RV10 rotary evaporator (German IKA company); SHB-Ⅲ circulating water vacuum pump (Gongyi Yingyu Huake Instrument Factory); digital constant temperature water bath HH-...

Embodiment 2

[0072] Instruments and materials

[0073] 1.1 Instrument

[0074]Waters Acquity UPLC H-CLass System ultra-high performance liquid chromatography (Waters, USA); METTLER AE240 electronic analytical balance (Mettler-Toledo (Shanghai) Instrument Co., Ltd.); IKARV10 rotary evaporator (IKA, Germany); KQ-250B ultrasonic cleaner (Kunshan Ultrasonic Instrument Co., Ltd.); SHB-Ⅲ circulating water vacuum pump (Gongyi Yingyu Huake Instrument Factory); digital constant temperature water bath HH-2 (Guohua Electric Co., Ltd.).

[0075] 1.2 Materials and reagents

[0076] The source of medicinal materials is shown in Table 4. It was identified by Professor Liu Yuan of Southwest University for Nationalities as the dry root of CyatHulaCapitata (Wall.) Moq., a plant of the family Amaranthaceae. -O-[α-L-rhamnopyranose (1→3)-β-D-glucopyranose]-oleanolic acid (HNX-3 for short) and 3-O-[α-L- Rhamnopyranose (1→3)-β-D-glucopyranose]-oleanolic acid-28-O-(β-D-glucopyranose) (referred to as HNX-5), fo...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a method of separating purification saponin glycosides composition from achyranthes longifolia makino. The oleanolic acid saponin glycosides composition has the functions of protecting a liver, regulating immunity, resisting inflammation, bacteria and virus, delaying senescence, preventing and curing cardiovascular disease and the like, and has a wide application prospect in the medicine and health product development. In addition, no report about using specific chemical composition to control the quality of achyranthes longifolia makino exists at present, and the separated oleanolic acid saponin glycosides is related to the drug effect of achyranthes longifolia makino to a certain degree or used as a material basis of detecting the quality of achyranthes longifolia makino. According to the method, achyranthes longifolia makino is separated to obtain the oleanolic acid saponin glycosides composition, higher purity can be guaranteed, and the method provides a certain material basis for an in-depth study of the achyranthes longifolia makino.

Description

technical field [0001] The invention relates to natural medicine chemistry, in particular to a method for separating and purifying saponin components from Achyranthes knuckles. Background technique [0002] Red Achyranthes bidentata is a commonly used clinical medicinal material in Yi medicine in Liangshan Yi Autonomous Prefecture of Sichuan, Chuxiong Yi Autonomous Prefecture of Yunnan, Guizhou and other Yi ethnic areas. It is the root of Cyathula Capitata (Wall.) Moq., a plant of the family Amaranthaceae, and is used to treat bruises, rheumatism, rheumatoid and other diseases. [0003] The domestic and foreign research on Achyranthes bidentata mainly focuses on Achyranthesbidentata Blume and Cyathula officinalis Kuan, which are commonly used in TCM clinical practice; there are few related studies on Achyranthes bidentata. Achyranthes bidentata is a commonly used medicinal material in Yi medicine in Liangshan Yi Autonomous Prefecture of Sichuan, Chuxiong Yi Autonomous Pref...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C07J63/00
CPCC07J63/008
Inventor 刘圆王景富王静霞李莹
Owner SOUTHWEST UNIVERSITY FOR NATIONALITIES