A method and device for judging the detection result of Treponema pallidum antibody

Abstract

The invention discloses a method and a device for judging the detection result of a treponema pallidum antibody. The method comprises the following steps: performing agglutination reaction on serum or plasma of a to-be-detected patient by the treponema pallidum antibody and performing reaction on the serum or plasma of the to-be-detected patient without the treponema pallidum antibody separately by a treponema pallidum gelatin agglutination test method to acquire respective sample reaction plates; obtaining pictures of a to-be-detected sample and the control sample reaction plates; performing imaging processing on the pictures to acquire a plurality of pixel points and corresponding agglutination color pixel values from the pictures, and converting the pictures into two-dimensional data for storage; comparing parameters, such as shape, peak value, ratio of peak height to peak width, peak valley, difference value between peak height and peak valley and agglutination ring size, of agglutination color gray value curves of a to-be-detected group and a control group with a standard threshold value to judge the detection result. According to the method and the device for judging the detection result of the treponema pallidum antibody, the detection result of the treponema pallidum antibody can be judged more accurately and the detection efficiency is improved.

Description

technical field [0001] The invention relates to a computer-aided judgment method and device for the detection result of Treponema pallidum antibody, in particular to a judgment method and device for the detection result of Treponema pallidum antibody based on the agglutination method. Background technique [0002] Syphilis is a chronic infectious disease caused by Treponema pallidum infection. The main modes of transmission are sexual contact, blood transmission and vertical transmission, which are extremely harmful. In recent years, the epidemic of syphilis has been on the rise and has become the most common sexually transmitted disease in my country. [0003] Syphilis is a treatable disease, and if diagnosed promptly and treated properly, its spread can be controlled. To effectively control the spread of syphilis, timely and accurate diagnosis is necessary. At present, the laboratory diagnosis of syphilis mainly includes direct etiological diagnosis, serological diagnosi...

AI Technical Summary

Problems solved by technology

In serological testing, Treponemal pallidum particle agglutination test (TPPA) has become the confirmatory test of syphilis screening test, and its importance is self-evident, but this method has obvious shortcomings: (1) TPPA test results are judged by naked eyes, and the results Not objective, poor reproducibility; (2) Weak positive results are easy to misjudge (unsure results can only be retested); (3) A series of dilutions are required for retesting, which is time-consuming and laborious, and in some cases the naked eye still cannot Can't judge negative or positive

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