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Gynaecological antibacterial gel and preparation method thereof

A gynecological and gel technology, applied in the field of gynecological antibacterial gel and its preparation, can solve the problems of weak self-protection awareness, decreased immunity, infection, etc., and achieve the effect of improving the body's immunity and acting quickly

Inactive Publication Date: 2017-12-15
厦门康心元聚生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Gynecological diseases include vaginitis, cervicitis, genital itching, odor, etc. The main reason is that women are susceptible to Candida albicans, Staphylococcus aureus, Streptococcus, large intestine Invasion of pathogens such as bacilli and viruses; some patients have weak self-protection awareness and do not pay enough attention in the early stage of infection, which will lead to more serious infections; in addition, due to bad living habits or high work pressure, some patients are immune Poor, leading to long-term cure of gynecological diseases, bringing great inconvenience to normal life
[0003] At present, there are many kinds of antibacterial drugs for the treatment of gynecological inflammation, mainly divided into suppositories, lotions, sprays, etc., but most of the drugs will damage the reproductive tract environment and the self-secretion function of the mucous membrane, resulting in the destruction of the reproductive local immunity. and cause pathogenic bacteria to develop drug resistance and drug resistance, and eventually inflammation recurs; in addition, some drugs have defects such as single antibacterial species and slow effect. How to solve the above technical deficiencies has become an urgent problem to be solved

Method used

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  • Gynaecological antibacterial gel and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] A gynecological antibacterial gel, comprising the following components in parts by weight: 0.5 part of Panax notoginseng extract, 0.2 part of aloe extract, 0.2 part of safflower extract, 0.3 part of Houttuynia cordata extract, and 0.2 part of Radix isatidis extract , 0.1 part of nano silver, 0.7 part of antibacterial peptide, 1.2 part of polyethylene glycol, 1 part of gel matrix, 60 parts of deionized water.

[0027] The mass addition ratio of bombesin and defensin in the antimicrobial peptide is 1:3; the gel matrix is ​​sodium alginate.

[0028] A preparation method of gynecological antibacterial gel, the method steps are as follows: S1: add various plant extracts to deionized water, stir at 45°C for 50min, and the stirring speed is 400rpm; S2: wait for the mixed solution prepared in S1 to drop After reaching room temperature, add nano-silver and gel matrix, stir for 30min, and the stirring speed is 100rpm; S3: add antibacterial peptide and polyethylene glycol to the m...

Embodiment 2

[0030] A gynecological antibacterial gel, comprising the following components in parts by weight: 1.2 parts of Panax notoginseng extract, 0.7 part of aloe extract, 0.7 part of safflower extract, 0.6 part of Houttuynia cordata extract, and 0.7 part of Radix isatidis extract , 0.3 parts of nano silver, 1.3 parts of antibacterial peptide, 1.6 parts of polyethylene glycol, 2 parts of gel matrix, 70 parts of deionized water.

[0031] The mass addition ratio of bombesin and defensin in the antimicrobial peptide is 1:6; the gel matrix is ​​hyaluronic acid.

[0032] A preparation method of gynecological antibacterial gel, the method steps are as follows: S1: add various plant extracts to deionized water, stir at 55°C for 60min, and the stirring speed is 500rpm; S2: wait for the mixed solution prepared in S1 to drop After reaching room temperature, add nano-silver and gel matrix, stir for 40min, and the stirring speed is 150rpm; S3: add antimicrobial peptide and polyethylene glycol to ...

Embodiment 3

[0034] A gynecological antibacterial gel, comprising the following components in parts by weight: 1.1 parts of Panax notoginseng extract, 0.5 part of aloe extract, 0.4 part of safflower extract, 0.5 part of Houttuynia cordata extract, and 0.6 part of Radix isatidis extract , 0.2 parts of nano silver, 1.0 parts of antibacterial peptide, 1.4 parts of polyethylene glycol, 1.5 parts of gel matrix, and 65 parts of deionized water.

[0035] The mass addition ratio of bombesin and defensin in the antibacterial peptide is 1:4; the gel matrix is ​​xanthan gum.

[0036] A preparation method of gynecological antibacterial gel, the method steps are as follows: S1: add various plant extracts to deionized water, stir at 50°C for 57min, and the stirring speed is 450rpm; S2: wait for the mixed solution prepared in S1 to drop After reaching room temperature, add nano-silver and gel matrix, stir for 32min, and the stirring speed is 110rpm; S3: add antibacterial peptide and polyethylene glycol t...

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Abstract

The invention discloses gynaecological antibacterial gel, which is prepared from radix notoginseng extracts, aloe extracts, safflower extracts, herba houttuyniae extracts, radix isatidis extracts, nano-silver, antibacterial peptide, polyethylene glycol, gel substrates and deionized water. The gynaecological antibacterial gel provided by the invention uses the plant extracts as major antibacterial agents; meanwhile, the nanometer silver and the antibacterial peptide are added; various antibacterial ingredients have the cooperated effects, so that the product has the broad-spectrum antibacterial effects; the effect taking speed is high; safety is realized; no side effect exists; in addition, the antibacterial peptide kills the bacteria and can also improve the body immunity and help human body to resist the invasion from pathogens. Through being proved by experiments, the gynaecological antibacterial gel has the obvious inhibition effects on escherichia coli, candida albicans, staphylococcus aureus and pseudomonas aeruginosa; the cure rate on vaginitis is as high as 98.2 percent.

Description

technical field [0001] The invention relates to the technical field of daily chemical products, in particular to a gynecological antibacterial gel and a preparation method thereof. Background technique [0002] Gynecological diseases seriously affect women's health. According to statistics, about 40% of my country's adult women are often plagued by various gynecological diseases and suffer unspeakably. Gynecological diseases include vaginitis, cervicitis, genital itching, odor, etc. The main reason is that women are susceptible to Candida albicans, Staphylococcus aureus, Streptococcus, large intestine Invasion of pathogens such as bacilli and viruses; some patients have weak self-protection awareness and do not pay enough attention in the early stage of infection, which will lead to more serious infections; in addition, due to bad living habits or high work pressure, some patients are immune Poor, resulting in long-term gynecological diseases, bring great inconvenience to n...

Claims

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Application Information

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IPC IPC(8): A61K9/06A61K47/36A61K47/10A61K38/10A61K38/16A61P15/02A61P31/04A61K36/896A61K36/886A61K33/38
CPCA61K9/0034A61K9/06A61K33/38A61K36/195A61K36/258A61K36/286A61K36/315A61K36/78A61K36/886A61K36/896A61K38/105A61K38/16A61K47/10A61K47/36A61K2300/00Y02A50/30
Inventor 雷来妹
Owner 厦门康心元聚生物科技有限公司
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