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Noninvasive aqueous humor trace substance analysis device of vector optical field polarization mode

A vector light field, polarization mode technology, applied in blood characterization devices, diagnostic recording/measurement, medical science, etc., can solve problems such as high requirements for mechanical structure positioning, increase interference factors, increase system complexity, etc., and achieve easy functions. The effect of expansion, simple method and easy realization

Active Publication Date: 2017-12-26
UNIV OF SHANGHAI FOR SCI & TECH
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  • Claims
  • Application Information

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Problems solved by technology

The prior technology uses photoelectric technology to detect trace glucose components in aqueous humor, which can monitor key indicators of diabetes or related health aspects. The eyeball and the return beam pass through the analyzer to measure the polarization direction change of the linearly polarized beam. Using the optical rotation characteristics of glucose, combined with the absorption spectrum of the return beam, the glucose content is obtained by multivariate equation analysis. It has complex structure, low monitoring sensitivity, poor anti-interference, Features such as low security; 2) The system uses the eye positioning system to detect the monitoring situation and compensate during information processing. While increasing the complexity of the system, it has not solved the problem of low monitoring sensitivity, increasing the interference factors, and further affecting the system. Reliability; 3) The device is large in size and requires high mechanical structure positioning, which makes it difficult to miniaturize and affects the scope of application

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  • Noninvasive aqueous humor trace substance analysis device of vector optical field polarization mode

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Embodiment Construction

[0016] The present invention will be further described below in conjunction with drawings and embodiments.

[0017] Such as figure 1 As shown, the vector light field polarization mode non-invasive aqueous humor trace substance analysis device of the present invention includes: a light source 1, a beam shaping component 2, a polarization adjustment component 3, an irradiation beam splitter 4, a reference beam splitter 6, and a reference beam sensor 7 , an information beam splitter 8, an information beam sensor 9, a frequency information analysis module 10, a vector interference pattern photoelectric collection component 11, and an information processing module 12.

[0018] A beam shaping component 2, a polarization adjusting component 3, and an irradiation beam splitter 4 are sequentially arranged on the outgoing optical path of the light source 1. The beam shaping component 2 shapes the beam to form a wide beam for irradiation, and the polarization adjusting component 3 adjust...

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Abstract

The invention relates to a noninvasive aqueous humor trace substance analysis device of a vector optical field polarization mode. Light, which is transmitted from a light source, passes through a light beam shaping part, a polarization adjusting part and an illuminating spectroscope and the light reaches to an eyeball; by virtue of the illuminating spectroscope, a broad-beam vector optical field is subjected to light splitting; a reference light beam is constituted by a reflected light beam; a reference light beam spectroscope and a reference light beam sensor are sequentially arranged on a light path of the reference light beam; a light beam light path, which is reflected by virtue of the illuminating spectroscope, of a light beam which is reflected by the eyeball is sequentially provided with an information light beam spectroscope and an information light beam sensor; an interference reference light beam, which is constituted by a reflected light beam of the reference light beam spectroscope and an interference information light beam, which is constituted by a reflected light beam of the information light beam spectroscope, are applied to vector optical field interference, and the vector optical field interference is received by virtue of a vector interference pattern photo-electric collection part. Evolution characteristics of a vector interference pattern is analyzed by virtue of an information processing module, so that information on concentration of aqueous humor trace substances is obtained. The device provided by the invention has the characteristics of being noninvasive, simple in method, convenient for implementation, high in sensitivity, high in reliability, high in stability, strong in anti-interference performance and the like.

Description

technical field [0001] The present invention relates to a trace substance analysis device in aqueous humor, in particular to an aqueous humor trace substance used in the fields of health monitoring, disease monitoring, life science, medical diagnosis, biotechnology, human-computer interaction, behavioral organization, intelligent perception, etc. The invention relates to a vector light field polarization mode non-invasive aqueous humor trace substance analysis device for substance analysis, which belongs to the technical field of aqueous humor trace substance analysis. Background technique [0002] The gap between the back of the cornea and the front of the iris and lens is called the anterior chamber, the central part is about 2.5-3mm deep, and the surrounding part is called the anterior chamber angle. Behind the iris, the annular space between the ciliary body and the equator of the lens is called the posterior chamber. The clear fluid that fills the anterior and posterio...

Claims

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Application Information

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IPC IPC(8): A61B3/14A61B3/00A61B5/1455A61B5/145A61B5/00
CPCA61B3/0008A61B3/14A61B5/14532A61B5/14558A61B5/6821
Inventor 高秀敏许恒深王冠学苗玉单新治包颖
Owner UNIV OF SHANGHAI FOR SCI & TECH