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A portable microfluidic chip imaging system

A microfluidic chip and imaging system technology, applied in the field of microfluidics, can solve problems such as difficult to maintain consistent height, angle and lighting conditions, contamination of scanner chemical reagents, poor repeatability of results, etc., to solve cleaning problems, Satisfactory effect and good repeatability

Active Publication Date: 2020-11-20
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The scanner is relatively large and not easy to carry, and the inside of the scanner will inevitably be in direct contact with the reaction area in the microfluidic chip during imaging, which will cause the inside of the scanner to be polluted by chemical reagents, which will cause cleaning problems Trouble, but also likely to cause safety hazards
In addition, the scanner vibrates significantly during imaging, which reduces the imaging quality
When obtaining the reaction results in the microfluidic chip through the mobile phone, it is difficult to keep the height, angle and lighting conditions of each shot consistent, so the repeatability of the captured results is poor

Method used

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  • A portable microfluidic chip imaging system

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Embodiment Construction

[0020] The present invention provides a portable microfluidic chip imaging system, which is composed of a microfluidic chip 3 and an illumination device 2. Taking the microfluidic channel with a snowflake shape in the center of the circular microfluidic chip 3 as an example, it includes One sample injection area 4, eight linear channels 5 and eight detection areas 6 are provided.

[0021] figure 1 It is a portable microfluidic chip imaging system provided by the present invention, and its specific implementation is as follows:

[0022] (1) The circular microfluidic chip 3 has a diameter of 50mm and a thickness of 5mm, and has a snowflake-shaped microfluidic channel in its center, including three parts: the sample injection area 4, the linear channel 5, and the detection area 6. The depth of the microfluidic channel is 1 mm, in which the diameter of the central sampling area 4 is 10 mm, the diameter of the surrounding 8 detection areas 6 is 8 mm, and the distance between the c...

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Abstract

The invention discloses a portable microfluidic chip imaging system. The imaging system ensures the consistency of the heights, the angles and the light conditions of all times of shooting when a reaction result in a microfluidic chip is acquired through a mobile phone and is low in requirement on the external environment, capable of greatly improving the accuracy of a read result, good in repeatability, satisfactory in effect, convenient to carry and very suitable for microfluidic chip imaging. The imaging system is small and exquisite in size and convenient to carry and cannot directly makecontact with a reaction region in the microfluidic chip, the condition that the interior of the imaging system is contaminated by chemical reagents cannot be caused, the cleaning problem is solved, the potential safety hazards are reduced, and the equipment does not generate obvious vibration like a scanner during imaging, so that the imaging system has the higher imaging quality.

Description

technical field [0001] The invention relates to a microfluidic chip imaging system, which belongs to the field of microfluidic control. [0002] technical background [0003] Microfluidic chip is an integrable technology platform, which is one of the research hotspots in the field of analytical chemistry. This technology integrates chemical and biological analysis processes on a chip, which has the characteristics of low cost and high sensitivity, and has been It has shown great potential in biosensing, cell screening, gene analysis, drug delivery, disease diagnosis and environmental monitoring. [0004] The reaction results in microfluidic chips often need to be captured by devices such as mobile phones and scanners. The scanner is relatively large and not easy to carry, and the inside of the scanner will inevitably be in direct contact with the reaction area in the microfluidic chip during imaging, which will cause the inside of the scanner to be polluted by chemical reage...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): H04N5/225H04N5/235G01N21/01B01L3/00
Inventor 王敏吴非逸
Owner ZHEJIANG UNIV
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