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Chemiluminescence kit for rapid diagnosis of ovarian cancer in early and middle stages

A chemiluminescence reagent and rapid diagnosis technology, which is applied in the fields of chemiluminescence/bioluminescence, disease diagnosis, and analysis through chemical reaction of materials, etc., which can solve the problems that affect the early detection and treatment of ovarian cancer and are difficult to meet the requirements of early rapid diagnosis and other problems, to achieve the effect of reducing detection cost, high accuracy, and reducing detection error

Inactive Publication Date: 2018-02-09
GUANGZHOU HENGTAI BIOTECH
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  • Application Information

AI Technical Summary

Problems solved by technology

Because the single detection of selected tumor markers often has great limitations, it is difficult to meet the requirements of early and rapid diagnosis
[0005] At present, there is no rapid and efficient diagnostic kit for ovarian cancer on the market, which seriously affects the early detection and treatment of ovarian cancer

Method used

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  • Chemiluminescence kit for rapid diagnosis of ovarian cancer in early and middle stages
  • Chemiluminescence kit for rapid diagnosis of ovarian cancer in early and middle stages
  • Chemiluminescence kit for rapid diagnosis of ovarian cancer in early and middle stages

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Embodiment Construction

[0031] The chemiluminescent kit for early and mid-stage rapid diagnosis of ovarian cancer of the present invention will be described in detail below in conjunction with the accompanying drawings and specific examples.

[0032] A chemiluminescence kit for rapid diagnosis of early and mid-stage ovarian cancer, including capture antibody, capture antibody blocking buffer, standard, HRP-labeled detection antibody, washing solution and chromogenic solution, etc. The tumor marker components are: galectin-3, transthyretin, cancer antigen-125 and human epididymis protein 4. The capture antibodies include monoclonal antibodies prepared separately from the four markers; the kit includes tumor marker standards, microwell plates coated with tumor marker monoclonal capture antibodies, horseradish peroxidase or alkaline phosphate Enzyme-labeled tumor marker monoclonal detection antibody, chemiluminescence substrate solution, concentrated washing solution. The horseradish peroxidase chemilu...

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Abstract

The invention discloses a chemiluminescence kit for rapid diagnosis of ovarian cancer in early and middle stages. Tumor markers comprise galectin-3, transthyretin, a cancer antigen 125 and a human epididymal protein 4. The kit comprises a tumor marker standard, a tumor marker monoclonal capture antibody-coated microwell plate, a horseradish peroxidase or alkaline phosphatase-labeled tumor marker monoclonal detection antibody, a chemiluminescent substrate solution and a concentrated scrubbing solution. The chemiluminescence kit has high sensitivity of 95% or more and strong accuracy of 95% or more, is low in cost and reduces operation steps and detection errors.

Description

Technical field: [0001] The invention relates to the field of reagent kits for cancer diagnosis and detection, in particular to a chemiluminescent reagent kit for rapid early diagnosis of ovarian cancer. Background technique: [0002] Ovarian malignant tumor is one of the common malignant tumors of female reproductive organs, which refers to malignant tumors growing on the ovary, and 90% to 95% of them are primary ovarian cancers. 60% to 70% of them are advanced when they go to the doctor, and the curative effect of advanced cases is not good. Therefore, although the incidence rate of ovarian cancer is lower than cervical cancer and endometrial cancer, ranking third among gynecological malignancies, its mortality rate exceeds the sum of cervical cancer and endometrial cancer, ranking first among gynecological cancers, and is a serious threat to women. greatest disease of health. [0003] Due to the complex embryonic development, tissue anatomy and endocrine function of the...

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Application Information

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IPC IPC(8): G01N33/574G01N33/68G01N33/535G01N21/76
CPCG01N33/57449G01N21/76G01N21/763G01N33/535G01N33/57484G01N33/6893G01N2800/36
Inventor 余跃飞
Owner GUANGZHOU HENGTAI BIOTECH