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Method for evaluating physical conditions, method for presenting information, and method for screening for substance capable of improving or preventing physical conditions

A body state and substance technology, applied in the field of body state evaluation, can solve problems such as difficult evaluation of skin state, changes, evaluation, etc.

Active Publication Date: 2018-04-17
MYSKIN株式会社 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, there is a problem that it is difficult to obtain an objective evaluation due to the subjective influence of the subjects on the questionnaire survey.
On the other hand, in image analysis, although objective indicators can be obtained, the skin texture changes depending on whether the face is cleansed, the application of foundation, skin cream, etc., so it is difficult to accurately evaluate the skin condition such problem
[0004] In addition, it has been found that the factors that affect the skin condition are not limited to the above-mentioned indicators, and there are skin conditions that are difficult to evaluate in the conventional technology that relies on the above-mentioned indicators

Method used

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  • Method for evaluating physical conditions, method for presenting information, and method for screening for substance capable of improving or preventing physical conditions
  • Method for evaluating physical conditions, method for presenting information, and method for screening for substance capable of improving or preventing physical conditions
  • Method for evaluating physical conditions, method for presenting information, and method for screening for substance capable of improving or preventing physical conditions

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0097]

[0098] 1,100 Japanese women aged 18 to 69 were randomly selected from prefectures other than Okinawa, and a questionnaire survey was conducted on age, skin quality, etc. In addition, with respect to the women who took the questionnaire, the bacterial flora of the facial skin was analyzed by the method shown below at the same time as the questionnaire.

[0099] (questionnaire)

[0100] Questionnaires were administered via the Internet and answered just before sampling.

[0101] (Analysis of bacterial communities)

[0102] Bacterial communities were analyzed according to figure 1 shown in the flowchart.

[0103] ・Contacting step S1 and peeling step S2

[0104] Prepare figure 2 Adhesive tape 1 shown. This pressure-sensitive adhesive tape 1 has a structure in which a coating layer 3 made of an adhesive is provided on a sheet-shaped tape base 2 as a base. Therefore, the contact step S1 can be easily performed by sticking to the skin of a person in the same manner...

Embodiment 3

[0118] Host factors that determine the amount of the largest constituent species, P. acnes, were investigated. As a result, it was learned that the relative amount of P. acnes showed a correlation with chronological age, and the amount of P. acnes decreased with age ( Figure 10 Left, boxplots, red indicates means for each age group). In addition, the amount of P. acnes has also been shown to correlate with the oiliness of the skin. Based on age and skin type (various types of oily, normal, dry skin) these two are divided into 1074 people, calculate the average value of the P.acnes bacterial count of each taxonomic group and plot ( Figure 10 right). As a result, it was observed that the amount of P. acnes bacteria showed a correlation with the degree of oiliness of the skin independently of age.

[0119] (Relationship between P.acnes bacterial count and acne)

[0120] Knowing that the onset of acne, the intensity of symptoms has been shown to correlate with the relative a...

Embodiment 4

[0124] (Relationship between P-F amount and acne)

[0125] Next, it was also learned that the amount of P-F (difference in the relative amount of bacterial species belonging to the phylum Proteobacteria and bacterial species belonging to the phylum Firmicutes) was also shown to correlate with acne symptoms. The samples were divided into 3 groups according to the P-F amount, and it was observed that for the group with small values ​​(samples with more Firmicutes than Proteobacteria), acne symptoms were severe ( Figure 13 ). It should be noted that the amount of P-F did not show age-related changes, therefore, no treatment was performed to remove the effect of age.

[0126] (Relationship between P-F amount and hair thinning and hair loss)

[0127] It is known that the amount of PF is also correlated with the symptoms of hair thinning and hair loss on the head. Using the questionnaire results obtained by self-evaluation, hair thinning was treated in the form of thinning hair ...

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Abstract

The purpose of the invention is to provide: a method for evaluating various physical conditions accurately; a method for presenting information utilizing the aforementioned method; and a method of screening for a substance capable of improving or preventing physical conditions. A method for evaluating a physical condition of a subject comprises the steps of: determining the value of an abundance of a skin flora, which is collected from the surface of the skin of the subject, on the surface of the skin or the value of a parameter calculated on the basis of the abundance, wherein the reference values for the correlation between the abundance or the parameter with the physical condition has been produced; and then comparing the value with the reference values.

Description

technical field [0001] The present invention relates to a method for evaluating physical state, a method for presenting useful ingredients, and a method for screening substances for improving or preventing physical state. Background technique [0002] In the past, the state of human skin was evaluated based on indicators such as tension (Japanese: ハリ), texture, spots, wrinkles, moisture content, oil content, and water loss (barrier function). As an evaluation method, image analysis (tension, texture, spots, wrinkles, etc.) of the skin surface disclosed in questionnaires, Patent Document 1, etc., and measurement by a machine (moisture content, oil content, moisture loss, etc.) are used. . [0003] However, there is a problem that it is difficult to obtain an objective evaluation because the questionnaire survey is largely influenced by the subjects' subjectivity. On the other hand, in image analysis, although objective indicators can be obtained, the skin texture changes de...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12Q1/689G16B20/00G16B20/20G16B40/30
CPCC12Q1/68C12N15/09G01N33/56911G01N2570/00G01N2800/20G16B20/00G16B40/00G16B40/30G16B20/20C12Q1/6869
Inventor 古俣麻希子立花广太白髭克彦须谷尚史
Owner MYSKIN株式会社
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