9 results about "Skin flora" patented technology

There is provided a resident-skin-flora-improving agent that is useful in keeping the skin in excellent condition. Specifically, there is provided a resident-skin-flora-improving agent in which sophorose is used. Sophorose is provided with functionality by which it is possible to promote proliferation of helpful bacteria that beneficially affect skin while suppressing growth of bacteria that could adversely affect the skin. The resident-skin-flora-improving agent can suitably be used for the object of maintaining balance of the resident skin flora and keeping the skin in excellent condition.

The application discloses a low-irritation borage oil nano-liposome, a diaper-care preparation and application of the diaper-care preparation in diaper rash of infants and young children, and belongs to the field of infant skin-care preparations. The nano-liposome is composed of the following components in percentage by weight: 0.5-2.0% of biodecolorized borage oil, 1.0-3.0% of chitosan oligosaccharide-ceramide binary membrane material, 0.3-1.0% of prebiotic skin flora regulator, 0.8-1.5% of pH 5.5 weak acid buffer system, 0.05-0.2% of edible-grade microencapsulated menthol, and the balance of sterile water for injection. The application also provides a diaper-care preparation containing the low-irritation borage oil nano-liposome, which is suitable for daily prevention and acute-phase intervention of infants and young children aged 0-36 months, has the characteristics of high bioavailability, low irritation, rapid repair and easy carrying, and has important clinical application value.

The present application relates to the daily chemical technology field, especially to a composition with multiple anti-aging effects and application thereof.The composition comprises retinol, palmitoyl tripeptide-1, palmitoyl tetrapeptide-7, lactobacillus / soybean milk fermentation product filtrate and resveratrol.The present application is a composition with a mild triple anti-aging system for promoting collagen regeneration and a preparation method thereof, which contains retinol, palmitoyl tripeptide-1, palmitoyl tetrapeptide-7, lactobacillus / soybean milk fermentation product filtrate and resveratrol, has obvious effects on skin epidermis and dermis aging, up-regulates skin flora balance, enhances the water-locking ability of the stratum corneum, improves the penetration rate of active ingredients, and increases cell vitality on the epidermis;in the epidermis+dermis, it has antioxidant and anti-inflammatory properties, the components are mild and have good absorption effect, and there is no need to establish tolerance, so that the skin resistance is consolidated, and it is especially suitable for sensitive skin.

The application discloses application of a Portulaca oleracea extracellular vesicle in resisting acne and regulating acne microecological flora. The Portulaca oleracea extracellular vesicle PDEVs provided by the application can significantly inhibit growth of Propionibacterium acnes, and has obvious bactericidal effect under a lower MIC condition, has less influence on skin beneficial bacteria, is helpful to maintaining or regulating skin microecological balance, and has the advantage of selectively regulating skin flora. Meanwhile, the PDEVs can significantly reduce mRNA expression levels of inflammatory factors IL-6, IL-8, IL-1beta and TNF-alpha of HaCaT cells under stimulation of inactivated Propionibacterium acnes and intracellular reactive oxygen species ROS levels, thereby reducing inflammatory reaction and oxidative stress reaction; the PDEVs have a synergistic effect in regulating skin microecology, inhibiting inflammatory reaction and relieving oxidative stress, have good biocompatibility and safety, and provide more choices for developing natural source active ingredients for preventing or improving acne.

The present invention can provide a method for preparing a fermented nano-emulsifier composition comprising a product obtained by fermenting an oil with a skin flora, and a skin-friendly composition by minimizing the contents of synthetic raw materials according to such a method. Further, it is possible to improve an emulsification power by forming a nano-emulsion in a size of nm, to be adopted to various formulations by enhancing stability of the composition, and to be easily applied to various formulations requiring a function of hypoallergenic skin due to minimization of the skin irritation.

An ostomy barrier, skin adhesive, accessory or a peristomal skin treatment comprises a population of non-pathogenic bacteria, fungi, algae, yeast or their lysates configured to limit proliferation of pathogenic organisms in or on peristomal skin or skin at other body sites and / or maintain healthy skin flora. The ostomy barrier, adhesive, accessory or peristomal skin treatment can also be configured to alter the peristomal or other skin environment to promote growth of a desirable or commensal population while discouraging growth of the pathogenic organisms.

The invention belongs to the technical field of cosmetics, and particularly relates to a composition for adjusting a skin micro-ecological flora structure and application of the composition in improving red skin. Specifically, aiming at the problem of skin flora unbalance, skin physiological characteristics and skin flora characteristics of the red crowd are selected for research, key bacteria which influence flora composition of the red crowd are screened, and common cosmetic raw materials are screened by using characteristic bacteria propionibacterium acnes. On the basis, formula matching is carried out based on the proliferation rule of the raw materials on skin characteristic bacteria, the formula is further applied to the formula, the safety of the formula and the skin redness improvement condition after people use the formula are verified, and a product suitable for the skin characteristics of the redness people is obtained. Tests prove that the composition can remarkably improve the diversity of florae of the reddish skin, reduce the sebum content, the percutaneous moisture loss rate and the a value, recover the skin barrier function and improve the reddish symptom, so that the composition has good practical application value.

The present application belongs to the technical field of cosmetics, and particularly relates to an oil-controlling and repairing microemulsion for regulating the flora of oily sensitive skin as well as a preparation method and application thereof. Specifically, the oil-controlling and repairing microemulsion is directed against the flora of oily sensitive skin and the physiological characteristics of the skin, regulates propionibacterium which is prone to cause skin problems of the oily sensitive skin, thereby regulating the skin flora structure, and simultaneously improves the oil secretion and skin barrier of the oily sensitive skin, so as to achieve the effect of oil control and repair. It is also unexpectedly found in the present application that the formed oil-controlling and repairing emulsion can promote the proliferation of functional skin bacteria Staphylococcus epidermidis, and has a synergistic effect on relieving the flora imbalance caused by the proliferation of propionibacterium of oily skin acne, thus having good practical application value.

The application discloses a staphylococcus epidermidis NCU-07, probiotic postbiotic and application, relates to the field of biological medicine technology. The staphylococcus epidermidis NCU-07 is preserved in the China General Microbiological Culture Collection Center on January 18, 2023, and the preservation number is CGMCC NO.26493. The strain is prepared into probiotic postbiotic, and the application of the probiotic postbiotic in combination with silver sulfadiazine cream and compound coptis oil ointment in a drug combination for treating skin burn wounds is provided. The probiotic postbiotic disclosed by the application is helpful to promote the healing of the Ⅱ degree burn wound of a patient, can enhance the therapeutic effect when being used in combination with silver sulfadiazine cream and compound coptis oil ointment, relieve the itching symptoms of the Ⅱ degree burn wound of the patient, has no obvious influence on the pain symptoms of the wound, increases the diversity of skin flora, can inhibit the colonization and proliferation of pathogenic microorganisms, and promote the proliferation of skin symbiotic bacteria.